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Volume 104(7);  February 13, 2007
This Week in PNAS
In This Issue
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2027–2028. doi: 10.1073/iti0707104.
PMCID: PMC1892932
Commentaries
Probing the interactions of proteins and nanoparticles
Jacob Klein
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2029–2030. Published online 2007 February 6. doi: 10.1073/pnas.0611610104.
PMCID: PMC1892940
Uniformity amid diversity in RNase P
Venkat Gopalan
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2031–2032. Published online 2007 February 7. doi: 10.1073/pnas.0611193104.
PMCID: PMC1892978
How to keep photoreceptors alive
Alan Bird
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2033–2034. Published online 2007 February 6. doi: 10.1073/pnas.0611014104.
PMCID: PMC1892987
Physical Sciences
Chemistry
From the Cover:
Understanding the nanoparticle–protein corona using methods to quantify exchange rates and affinities of proteins for nanoparticles
Tommy Cedervall, Iseult Lynch, Stina Lindman, Tord Berggård, Eva Thulin, Hanna Nilsson, Kenneth A. Dawson, and Sara Linse
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2050–2055. Published online 2007 January 31. doi: 10.1073/pnas.0608582104.
PMCID: PMC1892985
A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity
Juewen Liu, Andrea K. Brown, Xiangli Meng, Donald M. Cropek, Jonathan D. Istok, David B. Watson, and Yi Lu
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2056–2061. Published online 2007 February 6. doi: 10.1073/pnas.0607875104.
PMCID: PMC1892917
Substrate product equilibrium on a reversible enzyme, triosephosphate isomerase
Sharon Rozovsky and Ann E. McDermott
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2080–2085. Published online 2007 February 7. doi: 10.1073/pnas.0608876104.
PMCID: PMC1794347
Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini
Sean D. Taverna, Beatrix M. Ueberheide, Yifan Liu, Alan J. Tackett, Robert L. Diaz, Jeffrey Shabanowitz, Brian T. Chait, Donald F. Hunt, and C. David Allis
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2086–2091. Published online 2007 February 6. doi: 10.1073/pnas.0610993104.
PMCID: PMC1892956
Superoxide-mediated amplification of the oxygen-induced switch from [4Fe-4S] to [2Fe-2S] clusters in the transcriptional regulator FNR
Jason C. Crack, Jeffrey Green, Myles R. Cheesman, Nick E. Le Brun, and Andrew J. Thomson
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2092–2097. Published online 2007 January 31. doi: 10.1073/pnas.0609514104.
PMCID: PMC1892919
Loop formation in unfolded polypeptide chains on the picoseconds to microseconds time scale
Beat Fierz, Helmut Satzger, Christopher Root, Peter Gilch, Wolfgang Zinth, and Thomas Kiefhaber
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2163–2168. Published online 2007 February 6. doi: 10.1073/pnas.0611087104.
PMCID: PMC1794216
Kinetic models of redox-coupled proton pumping
Young C. Kim, Mårten Wikström, and Gerhard Hummer
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2169–2174. Published online 2007 February 7. doi: 10.1073/pnas.0611114104.
PMCID: PMC1892981
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry
An Chi, Curtis Huttenhower, Lewis Y. Geer, Joshua J. Coon, John E. P. Syka, Dina L. Bai, Jeffrey Shabanowitz, Daniel J. Burke, Olga G. Troyanskaya, and Donald F. Hunt
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2193–2198. Published online 2007 February 7. doi: 10.1073/pnas.0607084104.
PMCID: PMC1892997
Physics
Internal strain regulates the nucleotide binding site of the kinesin leading head
Changbong Hyeon and José N. Onuchic
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2175–2180. Published online 2007 February 7. doi: 10.1073/pnas.0610939104.
PMCID: PMC1892953
Biological Sciences
Biochemistry
mRNA maturation by two-step trans-splicing/polyadenylation processing in trypanosomes
Adriana V. Jäger, Javier G. De Gaudenzi, Alejandro Cassola, Iván D'Orso, and Alberto C. Frasch
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2035–2042. Published online 2007 January 31. doi: 10.1073/pnas.0611125104.
PMCID: PMC1892994
From the Cover:
Eukaryotic RNase P RNA mediates cleavage in the absence of protein
Ema Kikovska, Staffan G. Svärd, and Leif A. Kirsebom
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2062–2067. Published online 2007 February 6. doi: 10.1073/pnas.0607326104.
PMCID: PMC1892975
Diazonamide toxins reveal an unexpected function for ornithine δ-amino transferase in mitotic cell division
Gelin Wang, Libin Shang, Anthony W. G. Burgett, Patrick G. Harran, and Xiaodong Wang
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2068–2073. Published online 2007 February 7. doi: 10.1073/pnas.0610832104.
PMCID: PMC1894683
Therapeutic anticancer efficacy of a synthetic diazonamide analog in the absence of overt toxicity
Noelle S. Williams, Anthony W. G. Burgett, Ashley S. Atkins, Xiaodong Wang, Patrick G. Harran, and Steven L. McKnight
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2074–2079. Published online 2007 February 7. doi: 10.1073/pnas.0611340104.
PMCID: PMC1794345
Substrate product equilibrium on a reversible enzyme, triosephosphate isomerase
Sharon Rozovsky and Ann E. McDermott
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2080–2085. Published online 2007 February 7. doi: 10.1073/pnas.0608876104.
PMCID: PMC1794347
Long-distance combinatorial linkage between methylation and acetylation on histone H3 N termini
Sean D. Taverna, Beatrix M. Ueberheide, Yifan Liu, Alan J. Tackett, Robert L. Diaz, Jeffrey Shabanowitz, Brian T. Chait, Donald F. Hunt, and C. David Allis
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2086–2091. Published online 2007 February 6. doi: 10.1073/pnas.0610993104.
PMCID: PMC1892956
Superoxide-mediated amplification of the oxygen-induced switch from [4Fe-4S] to [2Fe-2S] clusters in the transcriptional regulator FNR
Jason C. Crack, Jeffrey Green, Myles R. Cheesman, Nick E. Le Brun, and Andrew J. Thomson
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2092–2097. Published online 2007 January 31. doi: 10.1073/pnas.0609514104.
PMCID: PMC1892919
Open-cap conformation of intramembrane protease GlpG
Yongcheng Wang and Ya Ha
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2098–2102. Published online 2007 February 2. doi: 10.1073/pnas.0611080104.
PMCID: PMC1892946
Cooperative assembly of higher-order Notch complexes functions as a switch to induce transcription
Yunsun Nam, Piotr Sliz, Warren S. Pear, Jon C. Aster, and Stephen C. Blacklow
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2103–2108. Published online 2007 February 6. doi: 10.1073/pnas.0611092104.
PMCID: PMC1892977
Structure of the cooperative Xis–DNA complex reveals a micronucleoprotein filament that regulates phage lambda intasome assembly
Mohamad A. Abbani, Christie V. Papagiannis, My D. Sam, Duilio Cascio, Reid C. Johnson, and Robert T. Clubb
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2109–2114. Published online 2007 February 7. doi: 10.1073/pnas.0607820104.
PMCID: PMC1893000
Site-specific DNA transesterification catalyzed by a restriction enzyme
Giedrius Sasnauskas, Bernard A. Connolly, Stephen E. Halford, and Virginijus Siksnys
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2115–2120. Published online 2007 January 31. doi: 10.1073/pnas.0608689104.
PMCID: PMC1785359
Reactive oxygen species detoxification by catalase is a major determinant of fecundity in the mosquito Anopheles gambiae
Randall J. DeJong, Lisa M. Miller, Alvaro Molina-Cruz, Lalita Gupta, Sanjeev Kumar, and Carolina Barillas-Mury
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2121–2126. Published online 2007 February 6. doi: 10.1073/pnas.0608407104.
PMCID: PMC1892935
Restoring species-specific posttransfer editing activity to a synthetase with a defunct editing domain
Julius SternJohn, Sanchita Hati, Paul G. Siliciano, and Karin Musier-Forsyth
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2127–2132. Published online 2007 February 5. doi: 10.1073/pnas.0611110104.
PMCID: PMC1892958
Discovery of growth hormone-releasing hormones and receptors in nonmammalian vertebrates
Leo T. O. Lee, Francis K. Y. Siu, Janice K. V. Tam, Ivy T. Y. Lau, Anderson O. L. Wong, Marie C. M. Lin, Hubert Vaudry, and Billy K. C. Chow
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2133–2138. Published online 2007 February 5. doi: 10.1073/pnas.0611008104.
PMCID: PMC1892924
Vaccinia virus D10 protein has mRNA decapping activity, providing a mechanism for control of host and viral gene expression
Susan Parrish, Wolfgang Resch, and Bernard Moss
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2139–2144. Published online 2007 February 5. doi: 10.1073/pnas.0611685104.
PMCID: PMC1793903
Disulfide formation as a probe of folding in GroEL–GroES reveals correct formation of long-range bonds and editing of incorrect short-range ones
Eun Sun Park, Wayne A. Fenton, and Arthur L. Horwich
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2145–2150. Published online 2007 February 5. doi: 10.1073/pnas.0610989104.
PMCID: PMC1793900
Dynamic oligomeric conversions of the cytoplasmic RCK domains mediate MthK potassium channel activity
Mario Meng-Chiang Kuo, Kent A. Baker, Lee Wong, and Senyon Choe
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2151–2156. Published online 2007 February 7. doi: 10.1073/pnas.0609085104.
PMCID: PMC1892972
Assessment of nitric oxide signals by triiodide chemiluminescence
Alfred Hausladen, Ruslan Rafikov, Michael Angelo, David J. Singel, Evgeny Nudler, and Jonathan S. Stamler
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2157–2162. Published online 2007 February 7. doi: 10.1073/pnas.0611191104.
PMCID: PMC1892991
Biophysics
Loop formation in unfolded polypeptide chains on the picoseconds to microseconds time scale
Beat Fierz, Helmut Satzger, Christopher Root, Peter Gilch, Wolfgang Zinth, and Thomas Kiefhaber
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2163–2168. Published online 2007 February 6. doi: 10.1073/pnas.0611087104.
PMCID: PMC1794216
Kinetic models of redox-coupled proton pumping
Young C. Kim, Mårten Wikström, and Gerhard Hummer
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2169–2174. Published online 2007 February 7. doi: 10.1073/pnas.0611114104.
PMCID: PMC1892981
Internal strain regulates the nucleotide binding site of the kinesin leading head
Changbong Hyeon and José N. Onuchic
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2175–2180. Published online 2007 February 7. doi: 10.1073/pnas.0610939104.
PMCID: PMC1892953
Direct measurement of force generation by actin filament polymerization using an optical trap
Matthew J. Footer, Jacob W. J. Kerssemakers, Julie A. Theriot, and Marileen Dogterom
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2181–2186. Published online 2007 February 2. doi: 10.1073/pnas.0607052104.
PMCID: PMC1892916
Thermodynamic analysis of progesterone receptor–promoter interactions reveals a molecular model for isoform-specific function
Keith D. Connaghan-Jones, Aaron F. Heneghan, Michael T. Miura, and David L. Bain
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2187–2192. Published online 2007 February 2. doi: 10.1073/pnas.0608848104.
PMCID: PMC1892943
Cell Biology
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry
An Chi, Curtis Huttenhower, Lewis Y. Geer, Joshua J. Coon, John E. P. Syka, Dina L. Bai, Jeffrey Shabanowitz, Daniel J. Burke, Olga G. Troyanskaya, and Donald F. Hunt
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2193–2198. Published online 2007 February 7. doi: 10.1073/pnas.0607084104.
PMCID: PMC1892997
Global proteomic profiling of phosphopeptides using electron transfer dissociation tandem mass spectrometry
Henrik Molina, David M. Horn, Ning Tang, Suresh Mathivanan, and Akhilesh Pandey
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2199–2204. Published online 2007 February 7. doi: 10.1073/pnas.0611217104.
PMCID: PMC1794346
Telomere dysfunction as a cause of genomic instability in Werner syndrome
Laure Crabbe, Anna Jauch, Colleen M. Naeger, Heidi Holtgreve-Grez, and Jan Karlseder
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2205–2210. Published online 2007 February 6. doi: 10.1073/pnas.0609410104.
PMCID: PMC1794219
Aquaglyceroporin PbAQP during intraerythrocytic development of the malaria parasite Plasmodium berghei
Dominique Promeneur, Yangjian Liu, Jorge Maciel, Peter Agre, Landon S. King, and Nirbhay Kumar
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2211–2216. Published online 2007 February 6. doi: 10.1073/pnas.0610843104.
PMCID: PMC1892982
Role of the C terminus of the ribonucleotide reductase large subunit in enzyme regeneration and its inhibition by Sml1
Zhen Zhang, Kui Yang, Chin-Chuan Chen, Jason Feser, and Mingxia Huang
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2217–2222. Published online 2007 February 2. doi: 10.1073/pnas.0611095104.
PMCID: PMC1892911
Retrolinkin, a membrane protein, plays an important role in retrograde axonal transport
Jia-Jia Liu, Jianqing Ding, Chengbiao Wu, Prasanthi Bhagavatula, Bianxiao Cui, Steve Chu, William C. Mobley, and Yanmin Yang
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2223–2228. Published online 2007 February 7. doi: 10.1073/pnas.0602222104.
PMCID: PMC1892971
Characterization of Z-DNA as a nucleosome-boundary element in yeast Saccharomyces cerevisiae
Ben Wong, Shuai Chen, Jin-Ah Kwon, and Alexander Rich
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2229–2234. Published online 2007 February 6. doi: 10.1073/pnas.0611447104.
PMCID: PMC1892989
Cell stress modulates the function of splicing regulatory protein RBM4 in translation control
Jung-Chun Lin, Min Hsu, and Woan-Yuh Tarn
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2235–2240. Published online 2007 February 6. doi: 10.1073/pnas.0611015104.
PMCID: PMC1893002
Regulation of yeast oscillatory dynamics
Douglas B. Murray, Manfred Beckmann, and Hiroaki Kitano
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2241–2246. Published online 2007 February 6. doi: 10.1073/pnas.0606677104.
PMCID: PMC1794218
X-ray fluorescence microscopy reveals large-scale relocalization and extracellular translocation of cellular copper during angiogenesis
Lydia Finney, Suneeta Mandava, Lyann Ursos, Wen Zhang, Diane Rodi, Stefan Vogt, Daniel Legnini, Jorg Maser, Francis Ikpatt, Olufunmilayo I. Olopade, and David Glesne
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2247–2252. Published online 2007 February 5. doi: 10.1073/pnas.0607238104.
PMCID: PMC1892952
Developmental Biology
Wnt signaling interacts with Shh to regulate taste papilla development
Ken Iwatsuki, Hong-Xiang Liu, Albert Grónder, Meredith A. Singer, Timothy F. Lane, Rudolf Grosschedl, Charlotte M. Mistretta, and Robert F. Margolskee
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2253–2258. Published online 2007 February 6. doi: 10.1073/pnas.0607399104.
PMCID: PMC1794217
Lifelong accumulation of bone in mice lacking Pten in osteoblasts
Ximeng Liu, Katia J. Bruxvoort, Cassandra R. Zylstra, Jiarong Liu, Rachel Cichowski, Marie-Claude Faugere, Mary L. Bouxsein, Chao Wan, Bart O. Williams, and Thomas L. Clemens
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2259–2264. Published online 2007 February 7. doi: 10.1073/pnas.0604153104.
PMCID: PMC1892939
Ecology
From the Cover:
Dietary sequestration of defensive steroids in nuchal glands of the Asian snake Rhabdophis tigrinus
Deborah A. Hutchinson, Akira Mori, Alan H. Savitzky, Gordon M. Burghardt, Xiaogang Wu, Jerrold Meinwald, and Frank C. Schroeder
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2265–2270. Published online 2007 February 6. doi: 10.1073/pnas.0610785104.
PMCID: PMC1892995
Evolution
Pattern pluralism and the Tree of Life hypothesis
W. Ford Doolittle and Eric Bapteste
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2043–2049. Published online 2007 January 29. doi: 10.1073/pnas.0610699104.
PMCID: PMC1892968
Adaptive genic evolution in the Drosophila genomes
Joshua A. Shapiro, Wei Huang, Chenhui Zhang, Melissa J. Hubisz, Jian Lu, David A. Turissini, Shu Fang, Hurng-Yi Wang, Richard R. Hudson, Rasmus Nielsen, Zhu Chen, and Chung-I Wu
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2271–2276. Published online 2007 February 6. doi: 10.1073/pnas.0610385104.
PMCID: PMC1892965
Adaptations to fluctuating selection in Drosophila
Ville Mustonen and Michael Lässig
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2277–2282. Published online 2007 February 7. doi: 10.1073/pnas.0607105104.
PMCID: PMC1892984
Genetics
From the Cover:
Targeted cell killing by reconstituted caspases
Dattananda S. Chelur and Martin Chalfie
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2283–2288. Published online 2007 February 5. doi: 10.1073/pnas.0610877104.
PMCID: PMC1892955
Death-effector domain-containing protein DEDD is an inhibitor of mitotic Cdk1/cyclin B1
Satoko Arai, Katsuhisa Miyake, Renate Voit, Shino Nemoto, Edward K. Wakeland, Ingrid Grummt, and Toru Miyazaki
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2289–2294. Published online 2007 February 5. doi: 10.1073/pnas.0611167104.
PMCID: PMC1793902
Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegans
Elizabeth Pradel, Yun Zhang, Nathalie Pujol, Tohey Matsuyama, Cornelia I. Bargmann, and Jonathan J. Ewbank
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2295–2300. Published online 2007 January 31. doi: 10.1073/pnas.0610281104.
PMCID: PMC1892944
Acute postnatal ablation of Hif-2α results in anemia
Michaela Gruber, Cheng-Jun Hu, Randall S. Johnson, Eric J. Brown, Brian Keith, and M. Celeste Simon
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2301–2306. Published online 2007 February 6. doi: 10.1073/pnas.0608382104.
PMCID: PMC1892942
Plasticity of genetic interactions in metabolic networks of yeast
Richard Harrison, Balázs Papp, Csaba Pál, Stephen G. Oliver, and Daniela Delneri
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2307–2312. Published online 2007 February 6. doi: 10.1073/pnas.0607153104.
PMCID: PMC1892960
Transcriptomic analysis of growth heterosis in larval Pacific oysters (Crassostrea gigas)
Dennis Hedgecock, Jing-Zhong Lin, Shannon DeCola, Christian D. Haudenschild, Eli Meyer, Donal T. Manahan, and Ben Bowen
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2313–2318. Published online 2007 February 2. doi: 10.1073/pnas.0610880104.
PMCID: PMC1790866
Immunology
Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6
Yeny Martinez de la Torre, Chiara Buracchi, Elena M. Borroni, Jana Dupor, Raffaella Bonecchi, Manuela Nebuloni, Fabio Pasqualini, Andrea Doni, Eleonora Lauri, Chiara Agostinis, Roberta Bulla, Donald N. Cook, Bodduluri Haribabu, Pierluigi Meroni, Daniel Rukavina, Luca Vago, Francesco Tedesco, Annunciata Vecchi, Sergio A. Lira, Massimo Locati, and Alberto Mantovani
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2319–2324. Published online 2007 February 5. doi: 10.1073/pnas.0607514104.
PMCID: PMC1892950
Mast cells contribute to initiation of autoantibody-mediated arthritis via IL-1
Peter A. Nigrovic, Bryce A. Binstadt, Paul A. Monach, Alyssa Johnsen, Michael Gurish, Yoichiro Iwakura, Christophe Benoist, Diane Mathis, and David M. Lee
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2325–2330. Published online 2007 February 2. doi: 10.1073/pnas.0610852103.
PMCID: PMC1892913
Medical Sciences
Amelioration of progressive renal injury by genetic manipulation of Klotho gene
Yoshisuke Haruna, Naoki Kashihara, Minoru Satoh, Naruya Tomita, Tamehachi Namikoshi, Tamaki Sasaki, Toshihiko Fujimori, Ping Xie, and Yashpal S. Kanwar
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2331–2336. Published online 2007 February 7. doi: 10.1073/pnas.0611079104.
PMCID: PMC1892974
Elimination of insulitis and augmentation of islet β cell regeneration via induction of chimerism in overtly diabetic NOD mice
Chunyan Zhang, Ivan Todorov, Chia-Lei Lin, Mark Atkinson, Fouad Kandeel, Stephen Forman, and Defu Zeng
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2337–2342. Published online 2007 January 31. doi: 10.1073/pnas.0611101104.
PMCID: PMC1785362
Identification of prostate cancer mRNA markers by averaged differential expression and their detection in biopsies, blood, and urine
V. Uma Bai, Ahmed Kaseb, Sheela Tejwani, George W. Divine, Evelyn R. Barrack, Mani Menon, Arthur B. Pardee, and G. Prem-Veer Reddy
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2343–2348. Published online 2007 February 5. doi: 10.1073/pnas.0610504104.
PMCID: PMC1892964
Lnk negatively regulates self-renewal of hematopoietic stem cells by modifying thrombopoietin-mediated signal transduction
Jun Seita, Hideo Ema, Jun Ooehara, Satoshi Yamazaki, Yuko Tadokoro, Akiko Yamasaki, Koji Eto, Satoshi Takaki, Kiyoshi Takatsu, and Hiromitsu Nakauchi
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2349–2354. Published online 2007 February 6. doi: 10.1073/pnas.0606238104.
PMCID: PMC1892983
Interleukin 7 reduces the levels of spontaneous apoptosis in CD4+ and CD8+ T cells from HIV-1-infected individuals
Lia Vassena, Michael Proschan, Anthony S. Fauci, and Paolo Lusso
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2355–2360. Published online 2007 February 6. doi: 10.1073/pnas.0610775104.
PMCID: PMC1892954
Morphological mechanism of the development of pulmonary emphysema in klotho mice
Atsuyasu Sato, Toyohiro Hirai, Akihiro Imura, Naoko Kita, Akiko Iwano, Shigeo Muro, Yo-ichi Nabeshima, Bela Suki, and Michiaki Mishima
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2361–2365. Published online 2007 February 6. doi: 10.1073/pnas.0607882104.
PMCID: PMC1892918
Ectopic brown adipose tissue in muscle provides a mechanism for differences in risk of metabolic syndrome in mice
Katrine Almind, Monia Manieri, William I. Sivitz, Saverio Cinti, and C. Ronald Kahn
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2366–2371. Published online 2007 February 5. doi: 10.1073/pnas.0610416104.
PMCID: PMC1892979
Microbiology
Virstatin inhibits dimerization of the transcriptional activator ToxT
Elizabeth A. Shakhnovich, Deborah T. Hung, Emily Pierson, Kyungae Lee, and John J. Mekalanos
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2372–2377. Published online 2007 February 5. doi: 10.1073/pnas.0611643104.
PMCID: PMC1892951
Biosynthesis of γ-butyrolactone autoregulators that switch on secondary metabolism and morphological development in Streptomyces
Jun-ya Kato, Nobutaka Funa, Hidenori Watanabe, Yasuo Ohnishi, and Sueharu Horinouchi
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2378–2383. Published online 2007 February 2. doi: 10.1073/pnas.0607472104.
PMCID: PMC1892969
Common mechanisms of target cell recognition and immunity for class II bacteriocins
Dzung B. Diep, Morten Skaugen, Zhian Salehian, Helge Holo, and Ingolf F. Nes
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2384–2389. Published online 2007 February 6. doi: 10.1073/pnas.0608775104.
PMCID: PMC1892938
The 3D structure of a periplasm-spanning platform required for assembly of group 1 capsular polysaccharides in Escherichia coli
Richard F. Collins, Konstantinos Beis, Changjiang Dong, Catherine H. Botting, Catherine McDonnell, Robert C. Ford, Bradley R. Clarke, Chris Whitfield, and James H. Naismith
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2390–2395. Published online 2007 February 5. doi: 10.1073/pnas.0607763104.
PMCID: PMC1793899
O-Specific polysaccharide conjugate vaccine-induced IgG antibodies prevent invasion of Shigella into Caco-2 cells and may be curative
Yehuda Chowers, Joachim Kirschner, Nathan Keller, Iris Barshack, Simon Bar-Meir, Shai Ashkenazi, Rachel Schneerson, John Robbins, and Justen H. Passwell
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2396–2401. Published online 2007 February 7. doi: 10.1073/pnas.0610833104.
PMCID: PMC1892925
Increasing NADH oxidation reduces overflow metabolism in Saccharomyces cerevisiae
G. N. Vemuri, M. A. Eiteman, J. E. McEwen, L. Olsson, and J. Nielsen
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2402–2407. Published online 2007 February 7. doi: 10.1073/pnas.0607469104.
PMCID: PMC1892921
Light-powering Escherichia coli with proteorhodopsin
Jessica M. Walter, Derek Greenfield, Carlos Bustamante, and Jan Liphardt
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2408–2412. Published online 2007 February 2. doi: 10.1073/pnas.0611035104.
PMCID: PMC1892948
Phase-variable expression of a family of glycoproteins imparts a dynamic surface to a symbiont in its human intestinal ecosystem
C. Mark Fletcher, Michael J. Coyne, David L. Bentley, Otto F. Villa, and Laurie E. Comstock
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2413–2418. Published online 2007 February 6. doi: 10.1073/pnas.0608797104.
PMCID: PMC1892957
An antibiotic produced by an insect-pathogenic bacterium suppresses host defenses through phenoloxidase inhibition
Ioannis Eleftherianos, Sam Boundy, Susan A. Joyce, Shazia Aslam, James W. Marshall, Russell J. Cox, Thomas J. Simpson, David J. Clarke, Richard H. ffrench-Constant, and Stuart E. Reynolds
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2419–2424. Published online 2007 February 6. doi: 10.1073/pnas.0610525104.
PMCID: PMC1892976
Neuroscience
From the Cover:
Monocyte chemoattractant protein 1 mediates retinal detachment-induced photoreceptor apoptosis
Toru Nakazawa, Toshio Hisatomi, Chifuyu Nakazawa, Kosuke Noda, Kazuichi Maruyama, Haicheng She, Akihisa Matsubara, Shinsuke Miyahara, Shintaro Nakao, Yuqin Yin, Larry Benowitz, Ali Hafezi-Moghadam, and Joan W. Miller
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2425–2430. Published online 2007 February 6. doi: 10.1073/pnas.0608167104.
PMCID: PMC1892947
A dominant mutation in Snap25 causes impaired vesicle trafficking, sensorimotor gating, and ataxia in the blind-drunk mouse
Alexander F. Jeans, Peter L. Oliver, Reuben Johnson, Marco Capogna, Jenny Vikman, Zoltán Molnár, Arran Babbs, Christopher J. Partridge, Albert Salehi, Martin Bengtsson, Lena Eliasson, Patrik Rorsman, and Kay E. Davies
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2431–2436. Published online 2007 February 5. doi: 10.1073/pnas.0610222104.
PMCID: PMC1793901
1-Methyl-4-phenylpyridinium induces synaptic dysfunction through a pathway involving caspase and PKCδ enzymatic activities
Yafell Serulle, Gerardo Morfini, Gustavo Pigino, Jorge E. Moreira, Mutsuyuki Sugimori, Scott T. Brady, and Rodolfo R. Llinás
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2437–2441. Published online 2007 February 7. doi: 10.1073/pnas.0611227104.
PMCID: PMC1892934
1-Methyl-4-phenylpyridinium affects fast axonal transport by activation of caspase and protein kinase C
G. Morfini, G. Pigino, K. Opalach, Y. Serulle, J. E. Moreira, M. Sugimori, R. R. Llinás, and S. T. Brady
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2442–2447. Published online 2007 February 7. doi: 10.1073/pnas.0611231104.
PMCID: PMC1892945
Spinal cholinergic interneurons regulate the excitability of motoneurons during locomotion
Gareth B. Miles, Robert Hartley, Andrew J. Todd, and Robert M. Brownstone
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2448–2453. Published online 2007 February 7. doi: 10.1073/pnas.0611134104.
PMCID: PMC1794344
Absence of metabotropic glutamate receptor-mediated plasticity in the neocortex of fragile X mice
Brian M. Wilson and Charles L. Cox
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2454–2459. Published online 2007 February 7. doi: 10.1073/pnas.0610875104.
PMCID: PMC1892931
Queen pheromone modulates brain dopamine function in worker honey bees
Kyle T. Beggs, Kelly A. Glendining, Nicola M. Marechal, Vanina Vergoz, Ikumi Nakamura, Keith N. Slessor, and Alison R. Mercer
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2460–2464. Published online 2007 February 7. doi: 10.1073/pnas.0608224104.
PMCID: PMC1892986
Menstrual cycle phase modulates reward-related neural function in women
Jean-Claude Dreher, Peter J. Schmidt, Philip Kohn, Daniella Furman, David Rubinow, and Karen Faith Berman
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2465–2470. Published online 2007 January 31. doi: 10.1073/pnas.0605569104.
PMCID: PMC1892961
Olfactory neurons expressing transient receptor potential channel M5 (TRPM5) are involved in sensing semiochemicals
Weihong Lin, Robert Margolskee, Gerald Donnert, Stefan W. Hell, and Diego Restrepo
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2471–2476. Published online 2007 January 31. doi: 10.1073/pnas.0610201104.
PMCID: PMC1892929
Direct action of gonadotropin in brain integrates behavioral and reproductive functions
Eun-Jin Yang, Brian T. Nasipak, and Darcy B. Kelley
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2477–2482. Published online 2007 February 6. doi: 10.1073/pnas.0608391104.
PMCID: PMC1893001
Differential requirement for MuSK and dystroglycan in generating patterns of neuromuscular innervation
Julie L. Lefebvre, Lili Jing, Sara Becaficco, Clara Franzini-Armstrong, and Michael Granato
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2483–2488. Published online 2007 February 6. doi: 10.1073/pnas.0610822104.
PMCID: PMC1892914
Cocaine-induced brain activation detected by dynamic manganese-enhanced magnetic resonance imaging (MEMRI)
Hanbing Lu, Zheng-Xiong Xi, Leah Gitajn, William Rea, Yihong Yang, and Elliot A. Stein
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2489–2494. Published online 2007 February 7. doi: 10.1073/pnas.0606983104.
PMCID: PMC1892936
Therapeutic effects of immunization with mutant superoxide dismutase in mice models of amyotrophic lateral sclerosis
Makoto Urushitani, Samer Abou Ezzi, and Jean-Pierre Julien
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2495–2500. Published online 2007 February 2. doi: 10.1073/pnas.0606201104.
PMCID: PMC1790867
Silencing of estrogen receptor α in the ventromedial nucleus of hypothalamus leads to metabolic syndrome
Sergei Musatov, Walter Chen, Donald W. Pfaff, Charles V. Mobbs, Xue-Jun Yang, Deborah J. Clegg, Michael G. Kaplitt, and Sonoko Ogawa
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2501–2506. Published online 2007 February 6. doi: 10.1073/pnas.0610787104.
PMCID: PMC1892990
Transcutaneous β-amyloid immunization reduces cerebral β-amyloid deposits without T cell infiltration and microhemorrhage
William V. Nikolic, Yun Bai, Demian Obregon, Huayan Hou, Takashi Mori, Jin Zeng, Jared Ehrhart, R. Douglas Shytle, Brian Giunta, Dave Morgan, Terrence Town, and Jun Tan
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2507–2512. Published online 2007 January 30. doi: 10.1073/pnas.0609377104.
PMCID: PMC1892920
Brain shape in human microcephalics and Homo floresiensis
Dean Falk, Charles Hildebolt, Kirk Smith, M. J. Morwood, Thomas Sutikna, Jatmiko, E. Wayhu Saptomo, Herwig Imhof, Horst Seidler, and Fred Prior
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2513–2518. Published online 2007 February 2. doi: 10.1073/pnas.0609185104.
PMCID: PMC1892980
Exchange protein activated by cAMP (Epac) mediates cAMP activation of p38 MAPK and modulation of Ca2+-dependent K+ channels in cerebellar neurons
Jeanne Ster, Frédéric De Bock, Nathalie C. Guérineau, Andrea Janossy, Stéphanie Barrère-Lemaire, Johannes L. Bos, Joël Bockaert, and Laurent Fagni
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2519–2524. Published online 2007 February 6. doi: 10.1073/pnas.0611031104.
PMCID: PMC1892910
Deletion of CASK in mice is lethal and impairs synaptic function
Deniz Atasoy, Susanne Schoch, Angela Ho, Krisztina A. Nadasy, Xinran Liu, Weiqi Zhang, Konark Mukherjee, Elena D. Nosyreva, Rafael Fernandez-Chacon, Markus Missler, Ege T. Kavalali, and Thomas C. Südhof
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2525–2530. Published online 2007 February 7. doi: 10.1073/pnas.0611003104.
PMCID: PMC1892970
Plant Biology
Indirect activation of a plant nucleotide binding site–leucine-rich repeat protein by a bacterial protease
Jules Ade, Brody J. DeYoung, Catherine Golstein, and Roger W. Innes
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2531–2536. Published online 2007 February 2. doi: 10.1073/pnas.0608779104.
PMCID: PMC1790868
Identification and functional expression of the Arabidopsis thaliana vacuolar glucose transporter 1 and its role in seed germination and flowering
Sirisha Aluri and Michael Büttner
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2537–2542. Published online 2007 February 6. doi: 10.1073/pnas.0610278104.
PMCID: PMC1892959
Two B3 domain transcriptional repressors prevent sugar-inducible expression of seed maturation genes in Arabidopsis seedlings
Hironaka Tsukagoshi, Atsushi Morikami, and Kenzo Nakamura
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2543–2547. Published online 2007 January 31. doi: 10.1073/pnas.0607940104.
PMCID: PMC1785360
The PsbQ protein defines cyanobacterial Photosystem II complexes with highest activity and stability
Johnna L. Roose, Yasuhiro Kashino, and Himadri B. Pakrasi
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2548–2553. Published online 2007 February 7. doi: 10.1073/pnas.0609337104.
PMCID: PMC1892988
Corrections
Correction for Ekstrand et al., Deletion of neuropeptide Y (NPY) 2 receptor in mice results in blockage of NPY-induced angiogenesis and delayed wound healing
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2554. Published online 2007 January 19. doi: 10.1073/pnas.0700089104.
PMCID: PMC1892937
Corrects: A. Jonas Ekstrand, et al. Deletion of neuropeptide Y (NPY) 2 receptor in mice results in blockage of NPY-induced angiogenesis and delayed wound healing. Proc Natl Acad Sci U S A. 2003 May 13; 100(10): 6033–6038.
Correction for Omilian et al., Ameiotic recombination in asexual lineages of Daphnia
Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2554. Published online 2007 January 19. doi: 10.1073/pnas.0611148104.
PMCID: PMC1892923
Corrects: Angela R. Omilian, et al. Ameiotic recombination in asexual lineages of Daphnia. Proc Natl Acad Sci U S A. 2006 December 5; 103(49): 18638–18643.
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