| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2007 May 1; 104(18): 7309–7310. doi: 10.1073/iti1807104.PMCID: PMC1863507 Commentaries It's elementary: Enhancing Fe3+ reduction improves rice yields Mary Lou Guerinot PMCID: PMC1863459 Pandemic influenza: Studying the lessons of history Stephen S. Morse PMCID: PMC1863464 From the liver to the brain across the blood–brain barrier Vivian I. Teichberg PMCID: PMC1863474 To sleep, perchance to integrate Howard Eichenbaum PMCID: PMC1863482 Physical Sciences Applied Mathematics An information-theoretic framework for resolving community structure in complex networks Martin Rosvall and Carl T. Bergstrom PMCID: PMC1855072 Deterministic characterization of stochastic genetic circuits Matthew Scott, Terence Hwa, and Brian Ingalls PMCID: PMC1863463 Applied Physical Sciences Structure and tie strengths in mobile communication networks J.-P. Onnela, J. Saramäki, J. Hyvönen, G. Szabó, D. Lazer, K. Kaski, J. Kertész, and A.-L. Barabási PMCID: PMC1863470 Protein-induced, previously unidentified twin form of calcite B. Pokroy, M. Kapon, F. Marin, N. Adir, and E. Zolotoyabko PMCID: PMC1863445 Chemistry Water surface is acidic Victoria Buch, Anne Milet, Robert Vácha, Pavel Jungwirth, and J. Paul Devlin PMCID: PMC1863452 Physics Phase-separation in ion-containing mixtures in electric fields Yoav Tsori and Ludwik Leibler PMCID: PMC1863475 Biological Sciences Anthropology European early modern humans and the fate of the Neandertals Erik Trinkaus PMCID: PMC1863481 Applied Biological Sciences From the Cover:
Mutational reconstructed ferric chelate reductase confers enhanced tolerance in rice to iron deficiency in calcareous soil Yasuhiro Ishimaru, Suyeon Kim, Takashi Tsukamoto, Hiroyuki Oki, Takanori Kobayashi, Satoshi Watanabe, Shinpei Matsuhashi, Michiko Takahashi, Hiromi Nakanishi, Satoshi Mori, and Naoko K. Nishizawa PMCID: PMC1854843 Biochemistry Functional, structural, and spectroscopic characterization of a glutathione-ligated [2Fe–2S] cluster in poplar glutaredoxin C1 Nicolas Rouhier, Hideaki Unno, Sibali Bandyopadhyay, Lluis Masip, Sung-Kun Kim, Masakazu Hirasawa, José Manuel Gualberto, Virginie Lattard, Masami Kusunoki, David B. Knaff, George Georgiou, Toshiharu Hase, Michael K. Johnson, and Jean-Pierre Jacquot PMCID: PMC1863468 The structure of a birnavirus polymerase reveals a distinct active site topology Junhua Pan, Vikram N. Vakharia, and Yizhi Jane Tao PMCID: PMC1855279 Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity Khandaker Siddiquee, Shumin Zhang, Wayne C. Guida, Michelle A. Blaskovich, Benjamin Greedy, Harshani R. Lawrence, M. L. Richard Yip, Richard Jove, Mark M. McLaughlin, Nicholas J. Lawrence, Said M. Sebti, and James Turkson PMCID: PMC1863497 Following evolution's lead to a single residue switch for diterpene synthase product outcome Meimei Xu, P. Ross Wilderman, and Reuben J. Peters PMCID: PMC1855280 Biophysics Deterministic characterization of stochastic genetic circuits Matthew Scott, Terence Hwa, and Brian Ingalls PMCID: PMC1863463 Subpicosecond oxygen trapping in the heme pocket of the oxygen sensor FixL observed by time-resolved resonance Raman spectroscopy Sergei G. Kruglik, Audrius Jasaitis, Klara Hola, Taku Yamashita, Ursula Liebl, Jean-Louis Martin, and Marten H. Vos PMCID: PMC1863486 Diversity in prion protein oligomerization pathways results from domain expansion as revealed by hydrogen/deuterium exchange and disulfide linkage Frederic Eghiaian, Thorsten Daubenfeld, Yann Quenet, Marieke van Audenhaege, Anne-Pascale Bouin, Guillaume van der Rest, Jeanne Grosclaude, and Human Rezaei PMCID: PMC1863451 An allosteric model of circadian KaiC phosphorylation Jeroen S. van Zon, David K. Lubensky, Pim R. H. Altena, and Pieter Rein ten Wolde PMCID: PMC1863508 Cell Biology Transmembrane protein Sun2 is involved in tethering mammalian meiotic telomeres to the nuclear envelope Johannes Schmitt, Ricardo Benavente, Didier Hodzic, Christer Höög, Colin L. Stewart, and Manfred Alsheimer PMCID: PMC1863442 βKlotho is required for metabolic activity of fibroblast growth factor 21 Yasushi Ogawa, Hiroshi Kurosu, Masaya Yamamoto, Animesh Nandi, Kevin P. Rosenblatt, Regina Goetz, Anna V. Eliseenkova, Moosa Mohammadi, and Makoto Kuro-o PMCID: PMC1855074 Akt1 governs breast cancer progression in vivo Xiaoming Ju, Sanjay Katiyar, Chenguang Wang, Manran Liu, Xuanmao Jiao, Shengwen Li, Jie Zhou, Jacob Turner, Michael P. Lisanti, Robert G. Russell, Susette C. Mueller, John Ojeifo, William S. Chen, Nissim Hay, and Richard G. Pestell PMCID: PMC1863437 Small-molecule synergist of the Wnt/β-catenin signaling pathway Qisheng Zhang, Michael B. Major, Shinichi Takanashi, Nathan D. Camp, Naoyuki Nishiya, Eric C. Peters, Mark H. Ginsberg, Xiaoying Jian, Paul A. Randazzo, Peter G. Schultz, Randall T. Moon, and Sheng Ding PMCID: PMC1863490 Repression of the PDCD2 gene by BCL6 and the implications for the pathogenesis of human B and T cell lymphomas Beverly W. Baron, Nancy Zeleznik-Le, Miriam J. Baron, Catherine Theisler, Dezheng Huo, Matthew D. Krasowski, Michael J. Thirman, Rebecca M. Baron, and Joseph M. Baron PMCID: PMC1863460 Developmental Biology Maternal Nanos represses hid/skl-dependent apoptosis to maintain the germ line in Drosophila embryos Kimihiro Sato, Yoshiki Hayashi, Yuichi Ninomiya, Shuji Shigenobu, Kayo Arita, Masanori Mukai, and Satoru Kobayashi PMCID: PMC1854842 Ecology Depth-mediated reversal of the effects of climate change on long-term growth rates of exploited marine fish Ronald E. Thresher, J. A. Koslow, A. K. Morison, and D. C. Smith PMCID: PMC1863487 Changes in nitrogen cycling during the past century in a northern hardwood forest Kendra K. McLauchlan, Joseph M. Craine, W. Wyatt Oswald, Peter R. Leavitt, and Gene E. Likens PMCID: PMC1863457 Pigeons combine compass and landmark guidance in familiar route navigation Dora Biro, Robin Freeman, Jessica Meade, Stephen Roberts, and Tim Guilford PMCID: PMC1863466 Stoichiometric controls of mercury dilution by growth Roxanne Karimi, Celia Y. Chen, Paul C. Pickhardt, Nicholas S. Fisher, and Carol L. Folt PMCID: PMC1863492 The impact of herbivore–plant coevolution on plant community structure Judith X. Becerra PMCID: PMC1855276 Evolution More genes underwent positive selection in chimpanzee evolution than in human evolution Margaret A. Bakewell, Peng Shi, and Jianzhi Zhang PMCID: PMC1863478 Multiple molecular evidences for a living mammalian fossil Dorothée Huchon, Pascale Chevret, Ursula Jordan, C. William Kilpatrick, Vincent Ranwez, Paulina D. Jenkins, Jürgen Brosius, and Jürgen Schmitz PMCID: PMC1863447 Immunology Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125 Kei-ichiro Arimoto, Hitoshi Takahashi, Takayuki Hishiki, Hideyuki Konishi, Takashi Fujita, and Kunitada Shimotohno PMCID: PMC1863485 Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression Amarnath Maitra, Fang Shen, Walter Hanel, Karen Mossman, Joel Tocker, David Swart, and Sarah L. Gaffen PMCID: PMC1863505 NKG2D recognition mediates Toll-like receptor 3 signaling-induced breakdown of epithelial homeostasis in the small intestines of mice Rongbin Zhou, Haiming Wei, Rui Sun, Jian Zhang, and Zhigang Tian PMCID: PMC1863471 Medical Sciences Targeting the β-catenin/TCF transcriptional complex in the treatment of multiple myeloma Kumar Sukhdeo, Mala Mani, Yunyu Zhang, Jui Dutta, Hiroshi Yasui, Melissa D. Rooney, Daniel E. Carrasco, Mei Zheng, Haiying He, Yu-Tzu Tai, Constantine Mitsiades, Kenneth C. Anderson, and Daniel R. Carrasco PMCID: PMC1863489 Nonrandom variations in human cancer ESTs indicate that mRNA heterogeneity increases during carcinogenesis Marie Brulliard, Dalia Lorphelin, Olivier Collignon, Walter Lorphelin, Benoit Thouvenot, Emmanuel Gothié, Sandrine Jacquenet, Virginie Ogier, Olivier Roitel, Jean-Marie Monnez, Pierre Vallois, Frances T. Yen, Olivier Poch, Marc Guenneugues, Gilles Karcher, Pierre Oudet, and Bernard E. Bihain PMCID: PMC1855071 Protection against Escherichia coli infection by antibody to the Staphylococcus aureus poly-N-acetylglucosamine surface polysaccharide Nuno Cerca, Tomás Maira-Litrán, Kimberly K. Jefferson, Martha Grout, Donald A. Goldmann, and Gerald B. Pier PMCID: PMC1863476 Nitric oxide mediates prostaglandins' deleterious effect on lipopolysaccharide-triggered murine fetal resorption J. Aisemberg, C. Vercelli, S. Billi, M. L. Ribeiro, D. Ogando, R. Meiss, S. M. McCann, V. Rettori, and A. M. Franchi PMCID: PMC1863444 Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck Shaoyu Zhou, Sushant Kachhap, Wenyue Sun, Guojun Wu, Alice Chuang, Luana Poeta, Lawson Grumbine, Suhail K. Mithani, Aditi Chatterjee, Wayne Koch, William H. Westra, Anirban Maitra, Chad Glazer, Michael Carducci, David Sidransky, Thomas McFate, Ajay Verma, and Joseph A. Califano PMCID: PMC1863503 Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans Shaoman Yin, Nancy Pham, Shuiliang Yu, Chaoyang Li, Poki Wong, Binggong Chang, Shin-Chung Kang, Emiliano Biasini, Po Tien, David A. Harris, and Man-Sun Sy PMCID: PMC1863438 Adult-onset pulmonary fibrosis caused by mutations in telomerase Kalliopi D. Tsakiri, Jennifer T. Cronkhite, Phillip J. Kuan, Chao Xing, Ganesh Raghu, Jonathan C. Weissler, Randall L. Rosenblatt, Jerry W. Shay, and Christine Kim Garcia PMCID: PMC1855917 Cyclophilin D inactivation protects axons in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis Michael Forte, Bruce G. Gold, Gail Marracci, Priya Chaudhary, Emy Basso, Dustin Johnsen, Xiaolin Yu, Jonathan Fowlkes, Micha Rahder, Katie Stem, Paolo Bernardi, and Dennis Bourdette PMCID: PMC1857227 Poor prognosis in carcinoma is associated with a gene expression signature of aberrant PTEN tumor suppressor pathway activity Lao H. Saal, Peter Johansson, Karolina Holm, Sofia K. Gruvberger-Saal, Qing-Bai She, Matthew Maurer, Susan Koujak, Adolfo A. Ferrando, Per Malmström, Lorenzo Memeo, Jorma Isola, Pär-Ola Bendahl, Neal Rosen, Hanina Hibshoosh, Markus Ringnér, Åke Borg, and Ramon Parsons PMCID: PMC1855070 The macrophage-stimulating protein pathway promotes metastasis in a mouse model for breast cancer and predicts poor prognosis in humans Alana L. Welm, Julie B. Sneddon, Carmen Taylor, Dimitry S. A. Nuyten, Marc J. van de Vijver, Bruce H. Hasegawa, and J. Michael Bishop PMCID: PMC1855278 Bradykinin B1 and B2 receptors both have protective roles in renal ischemia/reperfusion injury Masao Kakoki, Robert W. McGarrah, Hyung-Suk Kim, and Oliver Smithies PMCID: PMC1855073 From the Cover:
Public health interventions and epidemic intensity during the 1918 influenza pandemic Richard J. Hatchett, Carter E. Mecher, and Marc Lipsitch PMCID: PMC1849867 From the Cover:
The effect of public health measures on the 1918 influenza pandemic in U.S. cities Martin C. J. Bootsma and Neil M. Ferguson PMCID: PMC1849868 From the Cover:
Targeted delivery of proteins across the blood–brain barrier Brian J. Spencer and Inder M. Verma PMCID: PMC1857226 Microbiology The genome of Syntrophus aciditrophicus: Life at the thermodynamic limit of microbial growth Michael J. McInerney, Lars Rohlin, Housna Mouttaki, UnMi Kim, Rebecca S. Krupp, Luis Rios-Hernandez, Jessica Sieber, Christopher G. Struchtemeyer, Anamitra Bhattacharyya, John W. Campbell, and Robert P. Gunsalus PMCID: PMC1863511 Epstein–Barr virus and virus human protein interaction maps Michael A. Calderwood, Kavitha Venkatesan, Li Xing, Michael R. Chase, Alexei Vazquez, Amy M. Holthaus, Alexandra E. Ewence, Ning Li, Tomoko Hirozane-Kishikawa, David E. Hill, Marc Vidal, Elliott Kieff, and Eric Johannsen PMCID: PMC1863443 Discovery of platencin, a dual FabF and FabH inhibitor with in vivo antibiotic properties Jun Wang, Srinivas Kodali, Sang Ho Lee, Andrew Galgoci, Ronald Painter, Karen Dorso, Fred Racine, Mary Motyl, Lorraine Hernandez, Elizabeth Tinney, Steven L. Colletti, Kithsiri Herath, Richard Cummings, Oscar Salazar, Ignacio González, Angela Basilio, Francisca Vicente, Olga Genilloud, Fernando Pelaez, Hiranthi Jayasuriya, Katherine Young, Doris F. Cully, and Sheo B. Singh PMCID: PMC1863502 From the Cover:
Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118 Sinéad C. Corr, Yin Li, Christian U. Riedel, Paul W. O'Toole, Colin Hill, and Cormac G. M. Gahan PMCID: PMC1863472 In vivo imaging and genetic analysis link bacterial motility and symbiosis in the zebrafish gut John F. Rawls, Michael A. Mahowald, Andrew L. Goodman, Chad M. Trent, and Jeffrey I. Gordon PMCID: PMC1855277 A family of glycosylphosphatidylinositol-linked aspartyl proteases is required for virulence of Candida glabrata Rupinder Kaur, Biao Ma, and Brendan P. Cormack PMCID: PMC1863504 Neuroscience INAUGURAL ARTICLE by a Recently Elected Academy Member: Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons Christian S. Lobsiger, Séverine Boillée, and Don W. Cleveland PMCID: PMC1863491 Circadian desynchronization of core body temperature and sleep stages in the rat Trinitat Cambras, John R. Weller, Montserrat Anglès-Pujoràs, Michael L. Lee, Andrea Christopher, Antoni Díez-Noguera, James M. Krueger, and Horacio O. de la Iglesia PMCID: PMC1863469 Recruitment of an inhibitory hippocampal network after bursting in a single granule cell Masahiro Mori, Beat H. Gähwiler, and Urs Gerber PMCID: PMC1863441 Perinatal exposure to a noncoplanar polychlorinated biphenyl alters tonotopy, receptive fields, and plasticity in rat primary auditory cortex T. Kenet, R. C. Froemke, C. E. Schreiner, I. N. Pessah, and M. M. Merzenich PMCID: PMC1855918 Patterning of frontal cortex subdivisions by Fgf17 Jeremy A. Cholfin and John L. R. Rubenstein PMCID: PMC1863435 On-beam synchrony in the cerebellum as the mechanism for the timing and coordination of movement D. H. Heck, W. T. Thach, and J. G. Keating PMCID: PMC1863450 Separate oscillating cell groups in mouse suprachiasmatic nucleus couple photoperiodically to the onset and end of daily activity Natsuko Inagaki, Sato Honma, Daisuke Ono, Yusuke Tanahashi, and Ken-ichi Honma PMCID: PMC1857228 Demonstration of artificial visual percepts generated through thalamic microstimulation John S. Pezaris and R. Clay Reid PMCID: PMC1863473 Coherent neural representation of hand speed in humans revealed by MEG imaging Karim Jerbi, Jean-Philippe Lachaux, Karim N′Diaye, Dimitrios Pantazis, Richard M. Leahy, Line Garnero, and Sylvain Baillet PMCID: PMC1863498 Pharmacology A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein Matthew R. Whorton, Michael P. Bokoch, Søren G. F. Rasmussen, Bo Huang, Richard N. Zare, Brian Kobilka, and Roger K. Sunahara PMCID: PMC1863461 Physiology KSper, a pH-sensitive K+ current that controls sperm membrane potential Betsy Navarro, Yuriy Kirichok, and David E. Clapham PMCID: PMC1855916 Nonmammalian orthologs of prestin (SLC26A5) are electrogenic divalent/chloride anion exchangers Thorsten J. Schaechinger and Dominik Oliver PMCID: PMC1863495 Fatal gastrointestinal obstruction and hypertension in mice lacking nitric oxide-sensitive guanylyl cyclase Andreas Friebe, Evanthia Mergia, Oliver Dangel, Alexander Lange, and Doris Koesling PMCID: PMC1863512 Plant Biology The tiny eukaryote Ostreococcus provides genomic insights into the paradox of plankton speciation Brian Palenik, Jane Grimwood, Andrea Aerts, Pierre Rouzé, Asaf Salamov, Nicholas Putnam, Chris Dupont, Richard Jorgensen, Evelyne Derelle, Stephane Rombauts, Kemin Zhou, Robert Otillar, Sabeeha S. Merchant, Sheila Podell, Terry Gaasterland, Carolyn Napoli, Karla Gendler, Andrea Manuell, Vera Tai, Olivier Vallon, Gwenael Piganeau, Séverine Jancek, Marc Heijde, Kamel Jabbari, Chris Bowler, Martin Lohr, Steven Robbens, Gregory Werner, Inna Dubchak, Gregory J. Pazour, Qinghu Ren, Ian Paulsen, Chuck Delwiche, Jeremy Schmutz, Daniel Rokhsar, Yves Van de Peer, Hervé Moreau, and Igor V. Grigoriev PMCID: PMC1863510 Population Biology The generation of influenza outbreaks by a network of host immune responses against a limited set of antigenic types Mario Recker, Oliver G. Pybus, Sean Nee, and Sunetra Gupta PMCID: PMC1855915 Synchronous cycles of domestic dog rabies in sub-Saharan Africa and the impact of control efforts Katie Hampson, Jonathan Dushoff, John Bingham, Gideon Brückner, Y. H. Ali, and Andy Dobson PMCID: PMC1863501 Psychology From the Cover:
Human relational memory requires time and sleep Jeffrey M. Ellenbogen, Peter T. Hu, Jessica D. Payne, Debra Titone, and Matthew P. Walker PMCID: PMC1863467 Sustainability Science Depth-mediated reversal of the effects of climate change on long-term growth rates of exploited marine fish Ronald E. Thresher, J. A. Koslow, A. K. Morison, and D. C. Smith PMCID: PMC1863487 Social Sciences Political Sciences Political polarization Avinash K. Dixit and Jörgen W. Weibull PMCID: PMC1863477 Psychology Sacred bounds on rational resolution of violent political conflict Jeremy Ginges, Scott Atran, Douglas Medin, and Khalil Shikaki PMCID: PMC1863499 Social Sciences The emergence of simple languages in an experimental coordination game Reinhard Selten and Massimo Warglien PMCID: PMC1863456 Corrections Correction for Matsuda et al., DMY gene induces male development in genetically female (XX) medaka fish PMCID: PMC1863493 Corrects: Masaru Matsuda, et al. DMY gene induces male development in genetically female (XX) medaka fish. Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 3865–3870. Correction for Massaro et al., The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKCε inhibition PMCID: PMC1863488 Corrects: Marika Massaro, et al. The omega-3 fatty acid docosahexaenoate attenuates endothelial cyclooxygenase-2 induction through both NADP(H) oxidase and PKCε inhibition. Proc Natl Acad Sci U S A. 2006 October 10; 103(41): 15184–15189. Correction for Chowers et al., Specific polysaccharide conjugate vaccine-induced IgG antibodies prevent invasion of Shigella into Caco-2 cells and may be curative PMCID: PMC1863446 Corrects: Yehuda Chowers, et al. O-Specific polysaccharide conjugate vaccine-induced IgG antibodies prevent invasion of Shigella into Caco-2 cells and may be curative. Proc Natl Acad Sci U S A. 2007 February 13; 104(7): 2396–2401. Correction for Christen et al., DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in Caulobacter crescentus PMCID: PMC1863496 Corrects: Matthias Christen, et al. DgrA is a member of a new family of cyclic diguanosine monophosphate receptors and controls flagellar motor function in Caulobacter crescentus. Proc Natl Acad Sci U S A. 2007 March 6; 104(10): 4112–4117. |
