| | This journal provides immediate access to some articles. This Week in PNAS Proc Natl Acad Sci U S A. 2006 September 19; 103(38): 13899–13900. doi: 10.1073/iti3806103.PMCID: PMC1599883 Commentaries Sleep disruption, oxidative stress, and aging: New insights from fruit flies Chiara Cirelli PMCID: PMC1599884 Lakes of liquid CO2 in the deep sea Kenneth Nealson PMCID: PMC1599885 Physical Sciences Applied Physical Sciences Forced and unforced ocean temperature changes in Atlantic and Pacific tropical cyclogenesis regions B. D. Santer, T. M. L. Wigley, P. J. Gleckler, C. Bonfils, M. F. Wehner, K. AchutaRao, T. P. Barnett, J. S. Boyle, W. Brüggemann, M. Fiorino, N. Gillett, J. E. Hansen, P. D. Jones, S. A. Klein, G. A. Meehl, S. C. B. Raper, R. W. Reynolds, K. E. Taylor, and W. M. Washington PMCID: PMC1599886 Cytoskeletal polymer networks: The molecular structure of cross-linkers determines macroscopic properties B. Wagner, R. Tharmann, I. Haase, M. Fischer, and A. R. Bausch PMCID: PMC1599898 Chemistry From the Cover:
A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein Carsten Kötting, Marco Blessenohl, Yan Suveyzdis, Roger S. Goody, Alfred Wittinghofer, and Klaus Gerwert PMCID: PMC1599887 Direct screening of solution phase combinatorial libraries encoded with externally sensitized photolabile tags Rudresha Kottani, Roman A. Valiulin, and Andrei G. Kutateladze PMCID: PMC1599888 Protein surface hydration mapped by site-specific mutations Weihong Qiu, Ya-Ting Kao, Luyuan Zhang, Yi Yang, Lijuan Wang, Wesley E. Stites, Dongping Zhong, and Ahmed H. Zewail PMCID: PMC1599899 Engineering Self-assembled single-crystal silicon circuits on plastic Sean A. Stauth and Babak A. Parviz PMCID: PMC1599889 Mathematics The quantum MacMahon Master Theorem Stavros Garoufalidis, Thang T. Q. Lê, and Doron Zeilberger PMCID: PMC1599890 Biological Sciences Biochemistry Disulfide isomerization switches tissue factor from coagulation to cell signaling Jasimuddin Ahamed, Henri H. Versteeg, Marjolein Kerver, Vivien M. Chen, Barbara M. Mueller, Philip J. Hogg, and Wolfram Ruf PMCID: PMC1599891 Small molecules that bind the inner core of gp41 and inhibit HIV envelope-mediated fusion Gary Frey, Sophia Rits-Volloch, X.-Q. Zhang, Robert T. Schooley, Bing Chen, and Stephen C. Harrison PMCID: PMC1599892 Reconstitution of full-round uridine-deletion RNA editing with three recombinant proteins Xuedong Kang, Guanghan Gao, Kestrel Rogers, Arnold M. Falick, Sharleen Zhou, and Larry Simpson PMCID: PMC1599893 Molecular switch for alternative conformations of the HIV-1 V3 region: Implications for phenotype conversion Osnat Rosen, Michal Sharon, Sabine R. Quadt-Akabayov, and Jacob Anglister PMCID: PMC1599894 Crystal structure of human histone lysine-specific demethylase 1 (LSD1) Yong Chen, Yuting Yang, Feng Wang, Ke Wan, Kenichi Yamane, Yi Zhang, and Ming Lei PMCID: PMC1599895 The nucleotide-binding site of bacterial translation initiation factor 2 (IF2) as a metabolic sensor Pohl Milon, Eugene Tischenko, Jerneja Tomšic, Enrico Caserta, Gert Folkers, Anna La Teana, Marina V. Rodnina, Cynthia L. Pon, Rolf Boelens, and Claudio O. Gualerzi PMCID: PMC1599896 Ca2+/calmodulin-dependent protein kinase II (CaMKII) is activated by calmodulin with two bound calciums Julia M. Shifman, Mee H. Choi, Stefan Mihalas, Stephen L. Mayo, and Mary B. Kennedy PMCID: PMC1599897 Biophysics From the Cover:
A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein Carsten Kötting, Marco Blessenohl, Yan Suveyzdis, Roger S. Goody, Alfred Wittinghofer, and Klaus Gerwert PMCID: PMC1599887 Cytoskeletal polymer networks: The molecular structure of cross-linkers determines macroscopic properties B. Wagner, R. Tharmann, I. Haase, M. Fischer, and A. R. Bausch PMCID: PMC1599898 Protein surface hydration mapped by site-specific mutations Weihong Qiu, Ya-Ting Kao, Luyuan Zhang, Yi Yang, Lijuan Wang, Wesley E. Stites, Dongping Zhong, and Ahmed H. Zewail PMCID: PMC1599899 Solution structure of the complex between poxvirus-encoded CC chemokine inhibitor vCCI and human MIP-1β Li Zhang, Michele DeRider, Melissa A. McCornack, Shu-chuan Jao, Nancy Isern, Traci Ness, Richard Moyer, and Patricia J. LiWang PMCID: PMC1599900 AL-57, a ligand-mimetic antibody to integrin LFA-1, reveals chemokine-induced affinity up-regulation in lymphocytes Motomu Shimaoka, Minsoo Kim, Edward H. Cohen, Wei Yang, Nathan Astrof, Dan Peer, Azucena Salas, Audrey Ferrand, and Timothy A. Springer PMCID: PMC1599901 A molecular mechanism for osmolyte-induced protein stability Timothy O. Street, D. Wayne Bolen, and George D. Rose PMCID: PMC1564065 Mg2+–RNA interaction free energies and their relationship to the folding of RNA tertiary structures Dan Grilley, Ana Maria Soto, and David E. Draper PMCID: PMC1599903 Cell Biology Testing the importance of p27 degradation by the SCFskp2 pathway in murine models of lung and colon cancer Inke Timmerbeul, Carrie M. Garrett-Engele, Uta Kossatz, Xueyan Chen, Eduardo Firpo, Viktor Grünwald, Kenji Kamino, Ludwig Wilkens, Ulrich Lehmann, Jan Buer, Robert Geffers, Stefan Kubicka, Michael P. Manns, Peggy L. Porter, James M. Roberts, and Nisar P. Malek PMCID: PMC1599904 A bio-chemo-mechanical model for cell contractility Vikram S. Deshpande, Robert M. McMeeking, and Anthony G. Evans PMCID: PMC1560932 Developmental Biology Progesterone blocks estrogen-induced DNA synthesis through the inhibition of replication licensing Haiyan Pan, Yan Deng, and Jeffrey W. Pollard PMCID: PMC1599905 The transcriptome of human oocytes Arif Murat Kocabas, Javier Crosby, Pablo J. Ross, Hasan H. Otu, Zeki Beyhan, Handan Can, Wai-Leong Tam, Guilherme J. M. Rosa, Robert G. Halgren, Bing Lim, Emilio Fernandez, and Jose Bernardo Cibelli PMCID: PMC1599906 The cephalic neural crest exerts a critical effect on forebrain and midbrain development Sophie E. Creuzet, Salvador Martinez, and Nicole M. Le Douarin PMCID: PMC1599907 Ecology Phoretic nest parasites use sexual deception to obtain transport to their host's nest Leslie S. Saul-Gershenz and Jocelyn G. Millar PMCID: PMC1599908 Evolving resistance to obesity in an insect James Warbrick-Smith, Spencer T. Behmer, Kwang Pum Lee, David Raubenheimer, and Stephen J. Simpson PMCID: PMC1599909 Evolution From the Cover:
Ancestral reconstruction of the ligand-binding pocket of Family C G protein-coupled receptors Donghui Kuang, Yi Yao, David MacLean, Minghua Wang, David R. Hampson, and Belinda S. W. Chang PMCID: PMC1563994 Evolution of protein structural classes and protein sequence families In-Geol Choi and Sung-Hou Kim PMCID: PMC1560931 Genetics Identifying regulatory mechanisms using individual variation reveals key role for chromatin modification Su-In Lee, Dana Pe'er, Aimée M. Dudley, George M. Church, and Daphne Koller PMCID: PMC1599912 From the Cover:
Admixture mapping identifies 8q24 as a prostate cancer risk locus in African-American men Matthew L. Freedman, Christopher A. Haiman, Nick Patterson, Gavin J. McDonald, Arti Tandon, Alicja Waliszewska, Kathryn Penney, Robert G. Steen, Kristin Ardlie, Esther M. John, Ingrid Oakley-Girvan, Alice S. Whittemore, Kathleen A. Cooney, Sue A. Ingles, David Altshuler, Brian E. Henderson, and David Reich PMCID: PMC1599913 Extreme genetic risk for type 1A diabetes Theresa A. Aly, Akane Ide, Mohamed M. Jahromi, Jennifer M. Barker, Maria S. Fernando, Sunanda R. Babu, Liping Yu, Dongmei Miao, Henry A. Erlich, Pamela R. Fain, Katherine J. Barriga, Jill M. Norris, Marian J. Rewers, and George S. Eisenbarth PMCID: PMC1563993 Identification of DNMT1 (DNA methyltransferase 1) hypomorphs in somatic knockouts suggests an essential role for DNMT1 in cell survival Gerda Egger, Shinwu Jeong, Sonia G. Escobar, Connie C. Cortez, Tony W. H. Li, Yoshimasa Saito, Christine B. Yoo, Peter A. Jones, and Gangning Liang PMCID: PMC1599915 Immunology A conserved role for a GATA transcription factor in regulating epithelial innate immune responses Michael Shapira, Brigham J. Hamlin, Jiming Rong, Karen Chen, Michal Ronen, and Man-Wah Tan PMCID: PMC1599916 The p47 GTPases Igtp and Irgb10 map to the Chlamydia trachomatis susceptibility locus Ctrq-3 and mediate cellular resistance in mice Isaac Bernstein-Hanley, Jörn Coers, Zarine R. Balsara, Gregory A. Taylor, Michael N. Starnbach, and William F. Dietrich PMCID: PMC1599917 Medical Sciences Secondary lymphoid tissue chemokine (SLC/CCL21)/CCR7 signaling regulates fibrocytes in renal fibrosis Norihiko Sakai, Takashi Wada, Hitoshi Yokoyama, Martin Lipp, Satoshi Ueha, Kouji Matsushima, and Shuichi Kaneko PMCID: PMC1599918 Rapid nongenomic actions of thyroid hormone Yukio Hiroi, Hyung-Hwan Kim, Hao Ying, Fumihiko Furuya, Zhihong Huang, Tommaso Simoncini, Kensuke Noma, Kojiro Ueki, Ngoc-Ha Nguyen, Thomas S. Scanlan, Michael A. Moskowitz, Sheue-Yann Cheng, and James K. Liao PMCID: PMC1599919 β-Arrestin2 mediates nephrin endocytosis and impairs slit diaphragm integrity Ivo Quack, L. Christian Rump, Peter Gerke, Inga Walther, Tobias Vinke, Oliver Vonend, Thomas Grunwald, and Lorenz Sellin PMCID: PMC1564064 Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity Sebastian Oltean, Brian S. Sorg, Todd Albrecht, Vivian I. Bonano, Robert M. Brazas, Mark W. Dewhirst, and Mariano A. Garcia-Blanco PMCID: PMC1562548 Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo Owen J. Sansom, Valerie Meniel, Julie A. Wilkins, Alicia M. Cole, Karin A. Oien, Victoria Marsh, Thomas J. Jamieson, Carmen Guerra, Gabrielle H. Ashton, Mariano Barbacid, and Alan R. Clarke PMCID: PMC1599922 Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters Barbara Kroczynska, Rochelle Cutrone, Maurizio Bocchetta, Haining Yang, Amira G. Elmishad, Pamela Vacek, Maria Ramos-Nino, Brooke T. Mossman, Harvey I. Pass, and Michele Carbone PMCID: PMC1599923 Hedgehog modulates cell cycle regulators in stem cells to control hematopoietic regeneration Jennifer J. Trowbridge, Matthew P. Scott, and Mickie Bhatia PMCID: PMC1599924 Efficiency of carcinogenesis with and without a mutator mutation Robert A. Beckman and Lawrence A. Loeb PMCID: PMC1599925 A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia Ian J. Majewski, Donald Metcalf, Lisa A. Mielke, Danielle L. Krebs, Sarah Ellis, Marina R. Carpinelli, Sandra Mifsud, Ladina Di Rago, Jason Corbin, Nicos A. Nicola, Douglas J. Hilton, and Warren S. Alexander PMCID: PMC1599926 Identification of biomarkers that distinguish human papillomavirus (HPV)-positive versus HPV-negative head and neck cancers in a mouse model Katerina Strati, Henry C. Pitot, and Paul F. Lambert PMCID: PMC1599927 From the Cover:
Combinations of biomarkers predictive of later life mortality Tara L. Gruenewald, Teresa E. Seeman, Carol D. Ryff, Arun S. Karlamangla, and Burton H. Singer PMCID: PMC1599928 Microbiology From the Cover:
Microbial community in a sediment-hosted CO2 lake of the southern Okinawa Trough hydrothermal system Fumio Inagaki, Marcel M. M. Kuypers, Urumu Tsunogai, Jun-ichiro Ishibashi, Ko-ichi Nakamura, Tina Treude, Satoru Ohkubo, Miwako Nakaseama, Kaul Gena, Hitoshi Chiba, Hisako Hirayama, Takuro Nunoura, Ken Takai, Bo B. Jørgensen, Koki Horikoshi, and Antje Boetius PMCID: PMC1599929 Mechanisms of uropathogenic Escherichia coli persistence and eradication from the urinary tract Indira U. Mysorekar and Scott J. Hultgren PMCID: PMC1564066 Identification of Clostridium difficile toxin B cardiotoxicity using a zebrafish embryo model of intoxication Elaine E. Hamm, Daniel E. Voth, and Jimmy D. Ballard PMCID: PMC1599930 Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes Sagar B. Kudchodkar, Yongjun Yu, Tobi G. Maguire, and James C. Alwine PMCID: PMC1599931 Transcriptional activation by EBV nuclear antigen 1 is essential for the expression of EBV's transforming genes Markus Altmann, Dagmar Pich, Romana Ruiss, Jindong Wang, Bill Sugden, and Wolfgang Hammerschmidt PMCID: PMC1599932 Influenza A virus NS1 protein binds p85β and activates phosphatidylinositol-3-kinase signaling Benjamin G. Hale, David Jackson, Yun-Hsiang Chen, Robert A. Lamb, and Richard E. Randall PMCID: PMC1599933 Neuroscience The effect of anticipation and the specificity of sex differences for amygdala and hippocampus function in emotional memory Kristen L. Mackiewicz, Issidoros Sarinopoulos, Krystal L. Cleven, and Jack B. Nitschke PMCID: PMC1599934 A tropomyosin-related kinase B ligand is required for ERK activation, long-term synaptic facilitation, and long-term memory in Aplysia Shiv K. Sharma, Carolyn M. Sherff, Shara Stough, Vickie Hsuan, and Thomas J. Carew PMCID: PMC1599935 Central peptidergic ensembles associated with organization of an innate behavior Young-Joon Kim, Dušan Žitňan, Kook-Ho Cho, David A. Schooley, Akira Mizoguchi, and Michael E. Adams PMCID: PMC1599936 Physiology Pathogenesis and treatment of autosomal-dominant nephrogenic diabetes insipidus caused by an aquaporin 2 mutation Eisei Sohara, Tatemitsu Rai, Sung-Sen Yang, Keiko Uchida, Kosaku Nitta, Shigeru Horita, Mayuko Ohno, Akihiro Harada, Sei Sasaki, and Shinichi Uchida PMCID: PMC1599937 Continuous up-regulation of heat shock proteins in larvae, but not adults, of a polar insect Joseph P. Rinehart, Scott A. L. Hayward, Michael A. Elnitsky, Luke H. Sandro, Richard E. Lee, Jr, and David L. Denlinger PMCID: PMC1599938 Population Biology Predicting the epidemiological impact of antiretroviral allocation strategies in KwaZulu-Natal: The effect of the urban–rural divide David P. Wilson, James Kahn, and Sally M. Blower PMCID: PMC1599939 Cross-protective immunity can account for the alternating epidemic pattern of dengue virus serotypes circulating in Bangkok B. Adams, E. C. Holmes, C. Zhang, M. P. Mammen, Jr, S. Nimmannitya, S. Kalayanarooj, and M. Boots PMCID: PMC1599940 Psychology Functional organization of perisylvian activation during presentation of sentences in preverbal infants Ghislaine Dehaene-Lambertz, Lucie Hertz-Pannier, Jessica Dubois, Sébastien Mériaux, Alexis Roche, Mariano Sigman, and Stanislas Dehaene PMCID: PMC1599941 Progestin negatively affects hearing in aged women Patricia Guimaraes, Susan T. Frisina, Frances Mapes, Sherif F. Tadros, D. Robert Frisina, and Robert D. Frisina PMCID: PMC1560930 Social Sciences Psychology The effect of anticipation and the specificity of sex differences for amygdala and hippocampus function in emotional memory Kristen L. Mackiewicz, Issidoros Sarinopoulos, Krystal L. Cleven, and Jack B. Nitschke PMCID: PMC1599934 Feature-selective attention enhances color signals in early visual areas of the human brain M. M. Müller, S. Andersen, N. J. Trujillo, P. Valdés-Sosa, P. Malinowski, and S. A. Hillyard PMCID: PMC1599943 Corrections Correction for House et al., Permanent carbon dioxide storage in deep-sea sediments PMCID: PMC1599944 Corrects: Kurt Zenz House, et al. Permanent carbon dioxide storage in deep-sea sediments. Proc Natl Acad Sci U S A. 2006 August 15; 103(33): 12291–12295. Correction for Onyango et al., Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages PMCID: PMC1599945 Corrects: Patrick Onyango, et al. Monoallelic expression and methylation of imprinted genes in human and mouse embryonic germ cell lineages. Proc Natl Acad Sci U S A. 2002 August 6; 99(16): 10599–10604. Correction for Franco et al., Notch/Delta signaling constrains reengineering of pro-T cells by PU.1 PMCID: PMC1599946 Corrects: Christopher B. Franco, et al. Notch/Delta signaling constrains reengineering of pro-T cells by PU.1. Proc Natl Acad Sci U S A. 2006 August 8; 103(32): 11993–11998. |
