| | This journal provides immediate access to some articles. In This Issue Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14477–14478. doi: 10.1073/iti4105102.PMCID: PMC1253617 Commentaries Educating executive attention Karla Holmboe and Mark H. Johnson Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14479–14480. Published online 2005 October 3. doi: 10.1073/pnas.0507522102.PMCID: PMC1253612 Chromatin control of gene expression: Mixed-lineage leukemia methyltransferase SETs the stage for transcription Robert K. Slany Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14481–14482. Published online 2005 October 3. doi: 10.1073/pnas.0507401102.PMCID: PMC1253606 A positive feedback loop contributes to the deleterious effects of angiotensin Laurence L. Brunton Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14483–14484. Published online 2005 October 3. doi: 10.1073/pnas.0507070102.PMCID: PMC1253591 A breach in the blood-brain barrier Jonathan H. LeBowitz Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14485–14486. Published online 2005 October 3. doi: 10.1073/pnas.0507523102.PMCID: PMC1253613 From icy roads to salty streams Robert B. Jackson and Esteban G. Jobbágy Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14487–14488. Published online 2005 October 3. doi: 10.1073/pnas.0507389102.PMCID: PMC1253603 Physical Sciences Applied Mathematics Delay-induced stochastic oscillations in gene regulation Dmitri Bratsun, Dmitri Volfson, Lev S. Tsimring, and Jeff Hasty Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14593–14598. Published online 2005 September 30. doi: 10.1073/pnas.0503858102.PMCID: PMC1253555 Engineering The “robust yet fragile” nature of the Internet John C. Doyle, David L. Alderson, Lun Li, Steven Low, Matthew Roughan, Stanislav Shalunov, Reiko Tanaka, and Walter Willinger Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14497–14502. Published online 2005 October 4. doi: 10.1073/pnas.0501426102.PMCID: PMC1240072 An electromechanical material testing system for in situ electron microscopy and applications Yong Zhu and Horacio D. Espinosa Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14503–14508. Published online 2005 September 29. doi: 10.1073/pnas.0506544102.PMCID: PMC1253576 Corroboration of in vivo cartilage pressures with implications for synovial joint tribology and osteoarthritis causation Kjirste C. Morrell, W. Andrew Hodge, David E. Krebs, and Robert W. Mann Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14819–14824. Published online 2005 October 3. doi: 10.1073/pnas.0507117102.PMCID: PMC1253592 Biological Sciences Biochemistry From the Cover: ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells Giovanna Basile, Orazio Taglialatela-Scafati, Gianluca Damonte, Andrea Armirotti, Santina Bruzzone, Lucrezia Guida, Luisa Franco, Cesare Usai, Ernesto Fattorusso, Antonio De Flora, and Elena Zocchi Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14509–14514. Published online 2005 September 19. doi: 10.1073/pnas.0503691102.PMCID: PMC1216829 Imaging the nanomolar range of nitric oxide with an amplifier-coupled fluorescent indicator in living cells Moritoshi Sato, Naoki Hida, and Yoshio Umezawa Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14515–14520. Published online 2005 September 21. doi: 10.1073/pnas.0505136102.PMCID: PMC1253562 Structure of an extracellular giant hemoglobin of the gutless beard worm Oligobrachia mashikoi Nobutaka Numoto, Taro Nakagawa, Akiko Kita, Yuichi Sasayama, Yoshihiro Fukumori, and Kunio Miki Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14521–14526. Published online 2005 October 3. doi: 10.1073/pnas.0501541102.PMCID: PMC1253539 Structures of microfilament destabilizing toxins bound to actin provide insight into toxin design and activity John S. Allingham, Angela Zampella, Maria Valeria D'Auria, and Ivan Rayment Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14527–14532. Published online 2005 September 28. doi: 10.1073/pnas.0502089102.PMCID: PMC1253543 A transcriptional signaling pathway in the IFN system mediated by 2′-5′-oligoadenylate activation of RNase L Krishnamurthy Malathi, Jayashree M. Paranjape, Elena Bulanova, Minsub Shim, Jeanna M. Guenther-Johnson, Pieter W. Faber, Thomas E. Eling, Bryan R. G. Williams, and Robert H. Silverman Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14533–14538. Published online 2005 October 3. doi: 10.1073/pnas.0507551102.PMCID: PMC1239948 The DNA replication factor MCM5 is essential for Stat1-mediated transcriptional activation Marylynn Snyder, Wei He, and J. Jillian Zhang Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14539–14544. Published online 2005 September 30. doi: 10.1073/pnas.0507479102.PMCID: PMC1253610 Genistein, a natural product from soy, is a potent inhibitor of transthyretin amyloidosis Nora S. Green, Ted R. Foss, and Jeffery W. Kelly Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14545–14550. Published online 2005 September 29. doi: 10.1073/pnas.0501609102.PMCID: PMC1253540 Dual roles for cholesterol in mammalian cells Fang Xu, Scott D. Rychnovsky, Jitendra D. Belani, Helen H. Hobbs, Jonathan C. Cohen, and Robert B. Rawson Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14551–14556. Published online 2005 September 30. doi: 10.1073/pnas.0503590102.PMCID: PMC1239893 Inhibition of hypothalamic fatty acid synthase triggers rapid activation of fatty acid oxidation in skeletal muscle Seung Hun Cha, Zhiyuan Hu, Shigeru Chohnan, and M. Daniel Lane Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14557–14562. Published online 2005 October 3. doi: 10.1073/pnas.0507300102.PMCID: PMC1253598 Biophysics INAUGURAL ARTICLE by a Recently Elected Academy Member: Structural role of countertransport revealed in Ca 2+ pump crystal structure in the absence of Ca 2+Koji Obara, Naoyuki Miyashita, Cheng Xu, Itaru Toyoshima, Yuji Sugita, Giuseppe Inesi, and Chikashi Toyoshima Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14489–14496. Published online 2005 September 6. doi: 10.1073/pnas.0506222102.PMCID: PMC1253571 The experimental folding landscape of monomeric lactose repressor, a large two-domain protein, involves two kinetic intermediates Corey J. Wilson, Payel Das, Cecilia Clementi, Kathleen S. Matthews, and Pernilla Wittung-Stafshede Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14563–14568. Published online 2005 October 3. doi: 10.1073/pnas.0505808102.PMCID: PMC1253568 Characterization of the folding landscape of monomeric lactose repressor: Quantitative comparison of theory and experiment Payel Das, Corey J. Wilson, Giovanni Fossati, Pernilla Wittung-Stafshede, Kathleen S. Matthews, and Cecilia Clementi Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14569–14574. Published online 2005 October 3. doi: 10.1073/pnas.0505844102.PMCID: PMC1253569 Interfacial metal and antibody recognition Tongqing Zhou, Dean H. Hamer, Wayne A. Hendrickson, Quentin J. Sattentau, and Peter D. Kwong Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14575–14580. Published online 2005 September 29. doi: 10.1073/pnas.0507267102.PMCID: PMC1237054 Changes in hydrogen-bond strengths explain reduction potentials in 10 rubredoxin variants I-Jin Lin, Erika B. Gebel, Timothy E. Machonkin, William M. Westler, and John L. Markley Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14581–14586. Published online 2005 September 30. doi: 10.1073/pnas.0505521102.PMCID: PMC1239895 A label-free immunosensor array using single-chain antibody fragments Natalija Backmann, Christian Zahnd, Francois Huber, Alexander Bietsch, Andreas Plückthun, Hans-Peter Lang, Hans-Joachim Güntherodt, Martin Hegner, and Christoph Gerber Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14587–14592. Published online 2005 September 28. doi: 10.1073/pnas.0504917102.PMCID: PMC1253559 Delay-induced stochastic oscillations in gene regulation Dmitri Bratsun, Dmitri Volfson, Lev S. Tsimring, and Jeff Hasty Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14593–14598. Published online 2005 September 30. doi: 10.1073/pnas.0503858102.PMCID: PMC1253555 Cell Biology Heat-shock protein 60 is required for blastema formation and maintenance during regeneration Shinji Makino, Geoffrey G. Whitehead, Ching-Ling Lien, Soo Kim, Payal Jhawar, Akane Kono, Yasushi Kawata, and Mark T. Keating Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14599–14604. Published online 2005 October 4. doi: 10.1073/pnas.0507408102.PMCID: PMC1253607 Identification of K-ras as the major regulator for cytokine-dependent Akt activation in erythroid progenitors in vivo Jing Zhang and Harvey F. Lodish Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14605–14610. Published online 2005 October 3. doi: 10.1073/pnas.0507446102.PMCID: PMC1253609 Apical role for BRG1 in cytokine-induced promoter assembly Zuyao Ni, Elizabeth Karaskov, Tao Yu, Steven M. Callaghan, Sandy Der, David S. Park, Zhaodong Xu, Samantha G. Pattenden, and Rod Bremner Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14611–14616. Published online 2005 September 29. doi: 10.1073/pnas.0503070102.PMCID: PMC1253546 Multisite protein phosphorylation makes a good threshold but can be a poor switch Jeremy Gunawardena Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14617–14622. Published online 2005 September 29. doi: 10.1073/pnas.0507322102.PMCID: PMC1253599 MAP-1 is a mitochondrial effector of Bax Kuan Onn Tan, Nai Yang Fu, Sunil K. Sukumaran, Shing-Leng Chan, Jiunn Hian Kang, Kar Lai Poon, Bin Shun Chen, and Victor C. Yu Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14623–14628. Published online 2005 September 30. doi: 10.1073/pnas.0503524102.PMCID: PMC1239892 Rescue of ATPa3-deficient murine malignant osteopetrosis by hematopoietic stem cell transplantation in utero Annalisa Frattini, Harry C. Blair, Maria Grazia Sacco, Francesco Cerisoli, Francesca Faggioli, Enrica Mira Catò, Alessandra Pangrazio, Antonio Musio, Francesca Rucci, Cristina Sobacchi, Allison C. Sharrow, Sara E. Kalla, Maria Grazia Bruzzone, Roberto Colombo, Maria Cristina Magli, Paolo Vezzoni, and Anna Villa Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14629–14634. Published online 2005 September 29. doi: 10.1073/pnas.0507637102.PMCID: PMC1253616 RelA repression of RelB activity induces selective gene activation downstream of TNF receptors Emilie Jacque, Thierry Tchenio, Guillaume Piton, Paul-Henri Romeo, and Véronique Baud Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14635–14640. Published online 2005 September 28. doi: 10.1073/pnas.0507342102.PMCID: PMC1253600 Mechanism of radiation-induced bystander effect: Role of the cyclooxygenase-2 signaling pathway Hongning Zhou, Vladimir N. Ivanov, Joseph Gillespie, Charles R. Geard, Sally A. Amundson, David J. Brenner, Zengliang Yu, Howard B. Lieberman, and Tom K. Hei Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14641–14646. Published online 2005 October 3. doi: 10.1073/pnas.0505473102.PMCID: PMC1253564 Dynamic transport of SNARE proteins in the Golgi apparatus Pierre Cosson, Mariella Ravazzola, Oleg Varlamov, Thomas H. Söllner, Maurizio Di Liberto, Allen Volchuk, James E. Rothman, and Lelio Orci Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14647–14652. Published online 2005 September 30. doi: 10.1073/pnas.0507394102.PMCID: PMC1253604 Developmental Biology Hairless triggers reactivation of hair growth by promoting Wnt signaling Gerard M. J. Beaudoin, III, Jeanne M. Sisk, Pierre A. Coulombe, and Catherine C. Thompson Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14653–14658. Published online 2005 September 29. doi: 10.1073/pnas.0507609102.PMCID: PMC1253615 Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c Satyajit K. Karnik, Christina M. Hughes, Xueying Gu, Orit Rozenblatt-Rosen, Graeme W. McLean, Yue Xiong, Matthew Meyerson, and Seung K. Kim Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14659–14664. Published online 2005 September 29. doi: 10.1073/pnas.0503484102.PMCID: PMC1253549 Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors Haruhiko Akiyama‡, Jung-Eun Kim‡, Kazuhisa Nakashima, Gener Balmes, Naomi Iwai, Jian Min Deng, Zhaoping Zhang, James F. Martin, Richard R. Behringer, Takashi Nakamura, and Benoit de Crombrugghe Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14665–14670. Published online 2005 October 3. doi: 10.1073/pnas.0504750102.PMCID: PMC1239942 Iroquois transcription factors recognize a unique motif to mediate transcriptional repression in vivo Aphrodite Bilioni, Gavin Craig, Caroline Hill, and Helen McNeill Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14671–14676. Published online 2005 October 3. doi: 10.1073/pnas.0502480102.PMCID: PMC1239941 From the Cover: Long-term renewal of hair follicles from clonogenic multipotent stem cells Stéphanie Claudinot, Michael Nicolas, Hideo Oshima, Ariane Rochat, and Yann Barrandon Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14677–14682. Published online 2005 October 3. doi: 10.1073/pnas.0507250102.PMCID: PMC1253596 Environmental Sciences Ubiquity and diversity of ammonia-oxidizing archaea in water columns and sediments of the ocean Christopher A. Francis, Kathryn J. Roberts, J. Michael Beman, Alyson E. Santoro, and Brian B. Oakley Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14683–14688. Published online 2005 September 26. doi: 10.1073/pnas.0506625102.PMCID: PMC1253578 Evolution Mimivirus gene promoters exhibit an unprecedented conservation among all eukaryotes Karsten Suhre, Stéphane Audic, and Jean-Michel Claverie Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14689–14693. Published online 2005 October 3. doi: 10.1073/pnas.0506465102.PMCID: PMC1239944 A single domestication for potato based on multilocus amplified fragment length polymorphism genotyping David M. Spooner, Karen McLean, Gavin Ramsay, Robbie Waugh, and Glenn J. Bryan Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14694–14699. Published online 2005 October 3. doi: 10.1073/pnas.0507400102.PMCID: PMC1253605 EVOPRINTER, a multigenomic comparative tool for rapid identification of functionally important DNA Ward F. Odenwald, Wayne Rasband, Alexander Kuzin, and Thomas Brody Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14700–14705. Published online 2005 October 3. doi: 10.1073/pnas.0506915102.PMCID: PMC1239946 Consequences of reproductive barriers for genealogical discordance in the European corn borer Erik B. Dopman, Luisa Pérez, Steven M. Bogdanowicz, and Richard G. Harrison Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14706–14711. Published online 2005 October 3. doi: 10.1073/pnas.0502054102.PMCID: PMC1253542 Evidence from opsin genes rejects nocturnality in ancestral primates Ying Tan, Anne D. Yoder, Nayuta Yamashita, and Wen-Hsiung Li Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14712–14716. Published online 2005 September 28. doi: 10.1073/pnas.0507042102.PMCID: PMC1253590 Genetics Multiplexed variation scanning for 1,000 amplicons in hundreds of patients using mismatch repair detection (MRD) on tag arrays Malek Faham, Jianbiao Zheng, Martin Moorhead, Hossein Fakhrai-Rad, Eugeni Namsaraev, Kee Wong, Zhiyong Wang, Shu G. Chow, Liana Lee, Kent Suyenaga, Jennifer Reichert, Andrew Boudreau, James Eberle, Carsten Bruckner, Maneesh Jain, George Karlin-Neumann, Hywel B. Jones, Thomas D. Willis, Joseph D. Buxbaum, and Ronald W. Davis Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14717–14722. Published online 2005 October 3. doi: 10.1073/pnas.0506677102.PMCID: PMC1253580 Immunology Lymphoid neogenesis in chronic rejection: Evidence for a local humoral alloimmune response Olivier Thaunat, Anne-Christine Field, Jianping Dai, Liliane Louedec, Natacha Patey, Marie-Françoise Bloch, Chantal Mandet, Marie-France Belair, Patrick Bruneval, Olivier Meilhac, Blanche Bellon, Etienne Joly, Jean-Baptiste Michel, and Antonino Nicoletti Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14723–14728. Published online 2005 September 28. doi: 10.1073/pnas.0507223102.PMCID: PMC1253595 Netrin-1 inhibits leukocyte migration in vitro and in vivo Ngoc P. Ly, Katsumi Komatsuzaki, Iain P. Fraser, Anita A. Tseng, Parthak Prodhan, Kathryn J. Moore, and T. Bernard Kinane Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14729–14734. Published online 2005 October 3. doi: 10.1073/pnas.0506233102.PMCID: PMC1253572 How defects in central tolerance impinge on a deficiency in regulatory T cells Zhibin Chen, Christophe Benoist, and Diane Mathis Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14735–14740. Published online 2005 October 3. doi: 10.1073/pnas.0507014102.PMCID: PMC1253589 γδ T cell homeostasis is established in competition with αβ T cells and NK cells Jena D. French, Christina L. Roark, Willi K. Born, and Rebecca L. O'Brien Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14741–14746. Published online 2005 October 3. doi: 10.1073/pnas.0507520102.PMCID: PMC1239947 Natural killer cell and macrophage cooperation in MyD88-dependent innate responses to Plasmodium falciparum Myriam Baratin, Sophie Roetynck, Catherine Lépolard, Christine Falk, Serge Sawadogo, Satoshi Uematsu, Shizuo Akira, Bernhard Ryffel, Jean-Gérard Tiraby, Lena Alexopoulou, Carsten J. Kirschning, Jürg Gysin, Eric Vivier, and Sophie Ugolini Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14747–14752. Published online 2005 October 3. doi: 10.1073/pnas.0507355102.PMCID: PMC1253601 Medical Sciences Detection of the placental epigenetic signature of the maspin gene in maternal plasma Stephen S. C. Chim, Yu K. Tong, Rossa W. K. Chiu, Tze K. Lau, Tse N. Leung, Lisa Y. S. Chan, Cees B. M. Oudejans, Chunming Ding, and Y. M. Dennis Lo Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14753–14758. Published online 2005 October 3. doi: 10.1073/pnas.0503335102.PMCID: PMC1253547 A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope Michael D. Miller, Romas Geleziunas, Elisabetta Bianchi, Simon Lennard, Renee Hrin, Hangchun Zhang, Meiqing Lu, Zhiqiang An, Paolo Ingallinella, Marco Finotto, Marco Mattu, Adam C. Finnefrock, David Bramhill, James Cook, Debra M. Eckert, Richard Hampton, Mayuri Patel, Stephen Jarantow, Joseph Joyce, Gennaro Ciliberto, Riccardo Cortese, Ping Lu, William Strohl, William Schleif, Michael McElhaugh, Steven Lane, Christopher Lloyd, David Lowe, Jane Osbourn, Tristan Vaughan, Emilio Emini, Gaetano Barbato, Peter S. Kim, Daria J. Hazuda, John W. Shiver, and Antonello Pessi Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14759–14764. Published online 2005 October 3. doi: 10.1073/pnas.0506927102.PMCID: PMC1253587 From the Cover: MLL associates specifically with a subset of transcriptionally active target genes Thomas A. Milne, Yali Dou, Mary Ellen Martin, Hugh W. Brock, Robert G. Roeder, and Jay L. Hess Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14765–14770. Published online 2005 September 30. doi: 10.1073/pnas.0503630102.PMCID: PMC1253553 A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis Bo Ding, Jun-ichi Abe, Heng Wei, Haodong Xu, Wenyi Che, Toru Aizawa, Weimin Liu, Carlos A. Molina, Junichi Sadoshima, Burns C. Blaxall, Bradford C. Berk, and Chen Yan Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14771–14776. Published online 2005 September 26. doi: 10.1073/pnas.0506489102.PMCID: PMC1253575 From the Cover: Overcoming the blood-brain barrier with high-dose enzyme replacement therapy in murine mucopolysaccharidosis VII Carole Vogler, Beth Levy, Jeffrey H. Grubb, Nancy Galvin, Yun Tan, Emil Kakkis, Nadine Pavloff, and William S. Sly Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14777–14782. Published online 2005 September 14. doi: 10.1073/pnas.0506892102.PMCID: PMC1253584 Hepatitis B small surface antigen particles are octahedral Robert J. C. Gilbert, Lucy Beales, Donatienne Blond, Martha N. Simon, Beth Y. Lin, Francis V. Chisari, David I. Stuart, and David J. Rowlands Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14783–14788. Published online 2005 October 3. doi: 10.1073/pnas.0505062102.PMCID: PMC1253561 Profiling of genes expressed in peripheral blood mononuclear cells predicts glucocorticoid sensitivity in asthma patients Hakon Hakonarson, Unnur S. Bjornsdottir, Eva Halapi, Jonathan Bradfield, Florian Zink, Magali Mouy, Hildur Helgadottir, Asta S. Gudmundsdottir, Hjalti Andrason, Asdis E. Adalsteinsdottir, Kristleifur Kristjansson, Illugi Birkisson, Thor Arnason, Margret Andresdottir, David Gislason, Thorarinn Gislason, Jeffrey R. Gulcher, and Kari Stefansson Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14789–14794. Published online 2005 October 3. doi: 10.1073/pnas.0409904102.PMCID: PMC1253826 Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin Mei Li, Nadia Messaddeq, Marius Teletin, Jean-Louis Pasquali, Daniel Metzger, and Pierre Chambon Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14795–14800. Published online 2005 September 30. doi: 10.1073/pnas.0507385102.PMCID: PMC1253602 A nitric oxide processing defect of red blood cells created by hypoxia: Deficiency of S-nitrosohemoglobin in pulmonary hypertension Timothy J. McMahon, Gregory S. Ahearn, Martin P. Moya, Andrew J. Gow, Yuh-Chin T. Huang, Benjamin P. Luchsinger, Raphael Nudelman, Yun Yan, Abigail D. Krichman, Thomas M. Bashore, Robert M. Califf, David J. Singel, Claude A. Piantadosi, Victor F. Tapson, and Jonathan S. Stamler Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14801–14806. Published online 2005 October 3. doi: 10.1073/pnas.0506957102.PMCID: PMC1253588 Persistence of HIV-1 structural proteins and glycoproteins in lymph nodes of patients under highly active antiretroviral therapy Mikulas Popovic, Klara Tenner-Racz, Colleen Pelser, Hans-Jurgen Stellbrink, Jan van Lunzen, George Lewis, Vaniambadi S. Kalyanaraman, Robert C. Gallo, and Paul Racz Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14807–14812. Published online 2005 September 30. doi: 10.1073/pnas.0506857102.PMCID: PMC1253583 Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer Arshi Malik, Farrukh Afaq, Sami Sarfaraz, Vaqar M. Adhami, Deeba N. Syed, and Hasan Mukhtar Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14813–14818. Published online 2005 September 28. doi: 10.1073/pnas.0505870102.PMCID: PMC1253570 Corroboration of in vivo cartilage pressures with implications for synovial joint tribology and osteoarthritis causation Kjirste C. Morrell, W. Andrew Hodge, David E. Krebs, and Robert W. Mann Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14819–14824. Published online 2005 October 3. doi: 10.1073/pnas.0507117102.PMCID: PMC1253592 Induction of a proinflammatory program in normal human thyrocytes by the RET/PTC1 oncogene Maria Grazia Borrello, Luisella Alberti, Andrew Fischer, Debora Degl'Innocenti, Cristina Ferrario, Manuela Gariboldi, Federica Marchesi, Paola Allavena, Angela Greco, Paola Collini, Silvana Pilotti, Giuliana Cassinelli, Paola Bressan, Laura Fugazzola, Alberto Mantovani, and Marco A. Pierotti Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14825–14830. Published online 2005 October 3. doi: 10.1073/pnas.0503039102.PMCID: PMC1253545 Microbiology Marek's disease virus Meq transforms chicken cells via the v-Jun transcriptional cascade: A converging transforming pathway for avian oncoviruses Alon M. Levy, Oren Gilad, Liang Xia, Yoshihiro Izumiya, Jonathan Choi, Anya Tsalenko, Zohar Yakhini, Richard Witter, Lucy Lee, Carol J. Cardona, and Hsing-Jien Kung Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14831–14836. Published online 2005 October 3. doi: 10.1073/pnas.0506849102.PMCID: PMC1253582 Role of the WASP family proteins for Mycobacterium marinum actin tail formation Luisa M. Stamm, Melissa A. Pak, J. Hiroshi Morisaki, Scott B. Snapper, Klemens Rottner, Silvia Lommel, and Eric J. Brown Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14837–14842. Published online 2005 September 30. doi: 10.1073/pnas.0504663102.PMCID: PMC1239894 VirA and VirG activate the Ti plasmid repABC operon, elevating plasmid copy number in response to wound-released chemical signals Hongbaek Cho and Stephen C. Winans Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14843–14848. Published online 2005 September 29. doi: 10.1073/pnas.0503458102.PMCID: PMC1253548 Cyclophilin A is required for TRIM5α-mediated resistance to HIV-1 in Old World monkey cells Lionel Berthoux, Sarah Sebastian, Elena Sokolskaja, and Jeremy Luban Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14849–14853. Published online 2005 October 3. doi: 10.1073/pnas.0505659102.PMCID: PMC1239943 Neuroscience A unique gene expression signature discriminates familial Alzheimer's disease mutation carriers from their wild-type siblings Yosuke Nagasaka, Karin Dillner, Hayao Ebise, Reiji Teramoto, Hiroyuki Nakagawa, Lena Lilius, Karin Axelman, Charlotte Forsell, Akira Ito, Bengt Winblad, Toru Kimura, and Caroline Graff Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14854–14859. Published online 2005 September 30. doi: 10.1073/pnas.0504178102.PMCID: PMC1253556 Dynamics of sleep-wake cyclicity in developing rats Mark S. Blumberg, Adele M. H. Seelke, Steven B. Lowen, and Karl Æ. Karlsson Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14860–14864. Published online 2005 September 28. doi: 10.1073/pnas.0506340102.PMCID: PMC1253573 Autoantibodies against neuropeptides are associated with psychological traits in eating disorders Sergueï O. Fetissov, Jaanus Harro, Maiken Jaanisk, Anu Järv, Iris Podar, Jüri Allik, Ida Nilsson, Priya Sakthivel, Ann Kari Lefvert, and Tomas Hökfelt Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14865–14870. Published online 2005 September 29. doi: 10.1073/pnas.0507204102.PMCID: PMC1253594 Phospho-dependent binding of the clathrin AP2 adaptor complex to GABAA receptors regulates the efficacy of inhibitory synaptic transmission Josef T. Kittler, Guojun Chen, Stephan Honing, Yury Bogdanov, Kristina McAinsh, I. Lorena Arancibia-Carcamo, Jasmina N. Jovanovic, Menelas N. Pangalos, Volker Haucke, Zhen Yan, and Stephen J. Moss Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14871–14876. Published online 2005 September 28. doi: 10.1073/pnas.0506653102.PMCID: PMC1253579 The dosage of the neuroD2 transcription factor regulates amygdala development and emotional learning Chin-Hsing Lin, Stacey Hansen, Zhenshan Wang, Daniel R. Storm, Stephen J. Tapscott, and James M. Olson Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14877–14882. Published online 2005 October 3. doi: 10.1073/pnas.0506785102.PMCID: PMC1239945 Growth-associated protein GAP-43 and L1 act synergistically to promote regenerative growth of Purkinje cell axons in vivo Yi Zhang, Xuenong Bo, Ralf Schoepfer, Anthony J. D. G. Holtmaat, Joost Verhaagen, Piers C. Emson, A. Robert Lieberman, and Patrick N. Anderson Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14883–14888. Published online 2005 September 29. doi: 10.1073/pnas.0505164102.PMCID: PMC1253563 Ras activation of a Rac1 exchange factor, Tiam1, mediates neurotrophin-3-induced Schwann cell migration Junji Yamauchi, Yuki Miyamoto, Akito Tanoue, Eric M. Shooter, and Jonah R. Chan Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14889–14894. Published online 2005 October 3. doi: 10.1073/pnas.0507125102.PMCID: PMC1253593 Task-specific disruption of perceptual learning Aaron R. Seitz, Noriko Yamagishi, Birgit Werner, Naokazu Goda, Mitsuo Kawato, and Takeo Watanabe Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14895–14900. Published online 2005 October 3. doi: 10.1073/pnas.0505765102.PMCID: PMC1253567 Pattern-dependent, simultaneous plasticity differentially transforms the input-output relationship of a feedforward circuit Spencer LaVere Smith and Thomas Stephen Otis Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14901–14906. Published online 2005 September 30. doi: 10.1073/pnas.0505028102.PMCID: PMC1253560 Sex differences in estrogenic regulation of neuronal activity in neonatal cultures of ventromedial nucleus of the hypothalamus Jin Zhou, Donald W. Pfaff, and Gong Chen Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14907–14912. Published online 2005 October 4. doi: 10.1073/pnas.0507440102.PMCID: PMC1253608 Physiology Interstitial cells of Cajal mediate mechanosensitive responses in the stomach Kyung-Jong Won, Kenton M. Sanders, and Sean M. Ward Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14913–14918. Published online 2005 October 4. doi: 10.1073/pnas.0503628102.PMCID: PMC1253552 Plant Biology Conversion of nicotine to nornicotine in Nicotiana tabacum is mediated by CYP82E4, a cytochrome P450 monooxygenase Balazs Siminszky, Lily Gavilano, Steven W. Bowen, and Ralph E. Dewey Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14919–14924. Published online 2005 September 28. doi: 10.1073/pnas.0506581102.PMCID: PMC1253577 Psychology Attentional integration between anatomically distinct stimulus representations in early visual cortex John-Dylan Haynes, Jason Tregellas, and Geraint Rees Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14925–14930. Published online 2005 September 28. doi: 10.1073/pnas.0501684102.PMCID: PMC1253541 From the Cover: Training, maturation, and genetic influences on the development of executive attention M. Rosario Rueda, Mary K. Rothbart, Bruce D. McCandliss, Lisa Saccomanno, and Michael I. Posner Proc Natl Acad Sci U S A. 2005 October 11; 102(41): 14931–14936. Published online 2005 September 28. doi: 10.1073/pnas.0506897102.PMCID: PMC1253585 |