| | This journal provides immediate access to some articles. Commentaries Molecular targeting of cancer: Telomeres as targets Richard Hodes PMCID: PMC35393 Chipping away at stem cells Vi T. Chu and Fred H. Gage PMCID: PMC35394 Hidden robbers: The role of fungal haustoria in parasitism of plants Les J. Szabo and William R. Bushnell PMCID: PMC35395 Cell culture forensics Stephen J. O'Brien PMCID: PMC35396 Worms reveal essential functions for intermediate filaments Robert D. Goldman PMCID: PMC35397 Physical Sciences Chemistry Reversible encapsulation by self-assembling resorcinarene subunits Alexander Shivanyuk and Julius Rebek, Jr. PMCID: PMC35398 Dynamical hierarchy in transition states: Why and how does a system climb over the mountain? Tamiki Komatsuzaki and R. Stephen Berry PMCID: PMC35399 Biological Sciences Anthropology Primate postcrania from the late middle Eocene of Myanmar Russell L. Ciochon, Philip D. Gingerich, Gregg F. Gunnell, and Elwyn L. Simons PMCID: PMC35400 Biochemistry Visualization of biochemical networks in living cells Ingrid Remy and Stephen W. Michnick PMCID: PMC35401 Functional dynamics in the active site of the ribonuclease binase Lincong Wang, Yuxi Pang, Tina Holder, Jeffrey R. Brender, Alexander V. Kurochkin, and Erik R. P. Zuiderweg PMCID: PMC35402 Redox-dependent activation of CO dehydrogenase from Rhodospirillum rubrum Jongyun Heo, Cale M. Halbleib, and Paul W. Ludden PMCID: PMC35403 Communication between noncontacting macromolecules Jens Völker, Horst H. Klump, and Kenneth J. Breslauer PMCID: PMC35404 The origin of 15R-prostaglandins in the Caribbean coral Plexaura homomalla: Molecular cloning and expression of a novel cyclooxygenase Karin Valmsen, Ivar Järving, William E. Boeglin, Külliki Varvas, Reet Koljak, Tõnis Pehk, Alan R. Brash, and Nigulas Samel PMCID: PMC35405 Binding and disruption of phospholipid bilayers by supramolecular RNA complexes Alexandre Vlassov, Anastasia Khvorova, and Michael Yarus PMCID: PMC35406 In vitro characterization of DNA gyrase inhibition by microcin B17 analogs with altered bisheterocyclic sites Deborah B. Zamble, Deborah A. Miller, Jonathan G. Heddle, Anthony Maxwell, Christopher T. Walsh, and Florian Hollfelder PMCID: PMC35407 Deficiency of rds/peripherin causes photoreceptor death in mouse models of digenic and dominant retinitis pigmentosa Wojciech Kedzierski, Steven Nusinowitz, David Birch, Geoff Clarke, Roderick R. McInnes, Dean Bok, and Gabriel H. Travis PMCID: PMC35408 Tsg101, a homologue of ubiquitin-conjugating (E2) enzymes, binds the L domain in HIV type 1 Pr55Gag Lynn VerPlank, Fadila Bouamr, Tracy J. LaGrassa, Beth Agresta, Alexandra Kikonyogo, Jonathan Leis, and Carol A. Carter PMCID: PMC35409 Intramolecular secondary structure rearrangement by the kissing interaction of the Neurospora VS ribozyme Angela A. Andersen and Richard A. Collins PMCID: PMC35410 A unique phospholipid organization in bovine erythrocyte membranes J. Florin-Christensen, C. E. Suarez, M. Florin-Christensen, M. Wainszelbaum, W. C. Brown, T. F. McElwain, and G. H. Palmer PMCID: PMC35411 Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor Matthias Riewald and Wolfram Ruf PMCID: PMC35412 Biophysics Simple mechanochemistry describes the dynamics of kinesin molecules Michael E. Fisher and Anatoly B. Kolomeisky PMCID: PMC35413 Monitoring the GAP catalyzed H-Ras GTPase reaction at atomic resolution in real time Christoph Allin, Mohammad Reza Ahmadian, Alfred Wittinghofer, and Klaus Gerwert PMCID: PMC35414 Cytochrome c′ folding triggered by electron transfer: Fast and slow formation of four-helix bundles Jennifer C. Lee, Harry B. Gray, and Jay R. Winkler PMCID: PMC35415 Mechanical behavior in living cells consistent with the tensegrity model Ning Wang, Keiji Naruse, Dimitrije Stamenović, Jeffrey J. Fredberg, Srboljub M. Mijailovich, Iva Marija Tolić-Nørrelykke, Thomas Polte, Robert Mannix, and Donald E. Ingber PMCID: PMC35416 Configurational diffusion down a folding funnel describes the dynamics of DNA hairpins Anjum Ansari, Serguei V. Kuznetsov, and Yiqing Shen PMCID: PMC35417 Polarity and permeation profiles in lipid membranes Derek Marsh PMCID: PMC35418 Cell Biology Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK–ERK independent mechanism Jing Chen, Katsunori Fujii, Lixin Zhang, Thomas Roberts, and Haian Fu PMCID: PMC35419 Repression of TFII-I-dependent transcription by nuclear exclusion María Isabel Tussié-Luna, Dashzeveg Bayarsaihan, Frank H. Ruddle, and Ananda L. Roy PMCID: PMC35420 Nuclear particles containing RNA polymerase III complexes associated with the junctional plaque protein plakophilin 2 Claudia Mertens, Ilse Hofmann, Zhengxin Wang, Martin Teichmann, Setareh Sepehri Chong, Martina Schnölzer, and Werner W. Franke PMCID: PMC35421 A TRP homolog in Saccharomyces cerevisiae forms an intracellular Ca2+-permeable channel in the yeast vacuolar membrane Chris P. Palmer, Xin-Liang Zhou, Junyu Lin, Stephen H. Loukin, Ching Kung, and Yoshiro Saimi PMCID: PMC35422 A growth-constrained environment drives tumor progression in vivo S. Laconi, P. Pani, S. Pillai, D. Pasciu, D. S. R. Sarma, and E. Laconi PMCID: PMC35423 Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a Rhoda M. Alani, Alison Z. Young, and Clinton B. Shifflett PMCID: PMC35424 Clues to epidermal cancer proneness revealed by reconstruction of DNA repair-deficient xeroderma pigmentosum skin in vitro Françoise Bernerd, Daniel Asselineau, Corinne Vioux, Odile Chevallier-Lagente, Bakar Bouadjar, Alain Sarasin, and Thierry Magnaldo PMCID: PMC35425 Substrate-specific regulation of the ribosome– translocon junction by N-terminal signal sequences D. Thomas Rutkowski, Vishwanath R. Lingappa, and Ramanujan S. Hegde PMCID: PMC35426 A cytomegalovirus-encoded inhibitor of apoptosis that suppresses caspase-8 activation Anna Skaletskaya, Laura M. Bartle, Thomas Chittenden, A. Louise McCormick, Edward S. Mocarski, and Victor S. Goldmacher PMCID: PMC35427 The complete genome of the crenarchaeon Sulfolobus solfataricus P2 Qunxin She, Rama K. Singh, Fabrice Confalonieri, Yvan Zivanovic, Ghislaine Allard, Mariana J. Awayez, Christina C.-Y. Chan-Weiher, Ib Groth Clausen, Bruce A. Curtis, Anick De Moors, Gael Erauso, Cynthia Fletcher, Paul M. K. Gordon, Ineke Heikamp-de Jong, Alex C. Jeffries, Catherine J. Kozera, Nadine Medina, Xu Peng, Hoa Phan Thi-Ngoc, Peter Redder, Margaret E. Schenk, Cynthia Theriault, Niels Tolstrup, Robert L. Charlebois, W. Ford Doolittle, Michel Duguet, Terry Gaasterland, Roger A. Garrett, Mark A. Ragan, Christoph W. Sensen, and John Van der Oost PMCID: PMC35428 Identification of a subpopulation of rapidly self-renewing and multipotential adult stem cells in colonies of human marrow stromal cells David C. Colter, Ichiro Sekiya, and Darwin J. Prockop PMCID: PMC35429 Guanylyl cyclase C agonists regulate progression through the cell cycle of human colon carcinoma cells G. M. Pitari, M. D. Di Guglielmo, J. Park, S. Schulz, and S. A. Waldman PMCID: PMC35430 Developmental Biology Role of the iroquois3 homeobox gene in organizer formation Tetsuhiro Kudoh and Igor B. Dawid PMCID: PMC35431 Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways Ying Ying, Xiaoxia Qi, and Guang-Quan Zhao PMCID: PMC35432 Essential roles for four cytoplasmic intermediate filament proteins in Caenorhabditis elegans development Anton Karabinos, Henning Schmidt, Jens Harborth, Ralf Schnabel, and Klaus Weber PMCID: PMC35433 From the Cover:
Xenopus Bcl-XL selectively protects Rohon-Beard neurons from metamorphic degeneration Laurent Coen, David du Pasquier, Sébastien Le Mevel, Spencer Brown, Jamshed Tata, André Mazabraud, and Barbara A. Demeneix PMCID: PMC35434 Ecology Wheat leaves emit nitrous oxide during nitrate assimilation David R. Smart and Arnold J. Bloom PMCID: PMC35435 Life in the end-Permian dead zone Cindy V. Looy, Richard J. Twitchett, David L. Dilcher, Johanna H. A. Van Konijnenburg-Van Cittert, and Henk Visscher PMCID: PMC35436 Evolution Maternal effects and the evolution of aposematic signals Edmund D. Brodie, III and Aneil F. Agrawal PMCID: PMC35437 Extreme morphological and ecological homoplasy in tropical salamanders Gabriela Parra-Olea and David B. Wake PMCID: PMC35438 The cranium of Parapithecus grangeri, an Egyptian Oligocene anthropoidean primate Elwyn L. Simons PMCID: PMC35439 Related homing endonucleases I-BmoI and I-TevI use different strategies to cleave homologous recognition sites David R. Edgell and David A. Shub PMCID: PMC35440 Increased sexual activity reduces male immune function in Drosophila melanogaster Kurt A. McKean and Leonard Nunney PMCID: PMC35441 Genetics A mouse model for adenovirus gene delivery Tiziano Tallone, Stephen Malin, Annika Samuelsson, Johannes Wilbertz, Mitsue Miyahara, Kensaku Okamoto, Lorenz Poellinger, Lennart Philipson, and Sven Pettersson PMCID: PMC35442 The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia Huaqi Jiang, Rong Guo, and Jo Anne Powell-Coffman PMCID: PMC35443 Hd6, a rice quantitative trait locus involved in photoperiod sensitivity, encodes the α subunit of protein kinase CK2 Yuji Takahashi, Ayahiko Shomura, Takuji Sasaki, and Masahiro Yano PMCID: PMC35444 Genetic fidelity under harsh conditions: Analysis of spontaneous mutation in the thermoacidophilic archaeon Sulfolobus acidocaldarius Dennis W. Grogan, Geraldine T. Carver, and John W. Drake PMCID: PMC35445 From the Cover:
From hematopoiesis to neuropoiesis: Evidence of overlapping genetic programs Alexey V. Terskikh, Mathew C. Easterday, Linheng Li, Leroy Hood, Harley I. Kornblum, Daniel H. Geschwind, and Irving L. Weissman PMCID: PMC35446 Genes linked by fusion events are generally of the same functional category: A systematic analysis of 30 microbial genomes Itai Yanai, Adnan Derti, and Charles DeLisi PMCID: PMC35447 Localization of atherosclerosis susceptibility loci to chromosomes 4 and 6 using the Ldlr knockout mouse model Carrie L. Welch, Sara Bretschger, Nashat Latib, Mikhail Bezouevski, Yan Guo, Nick Pleskac, Chien-Ping Liang, Courtenay Barlow, Hayes Dansky, Jan L. Breslow, and Alan R. Tall PMCID: PMC35448 Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival Ajay N. Jain, Koei Chin, Anne-Lise Børresen-Dale, Bjorn K. Erikstein, Per Eystein Lonning, Rolf Kaaresen, and Joe W. Gray PMCID: PMC35449 Immunology Chemokine receptor 2 serves an early and essential role in resistance to Mycobacterium tuberculosis Wendy Peters, Holly M. Scott, Henry F. Chambers, JoAnne L. Flynn, Israel F. Charo, and Joel D. Ernst PMCID: PMC35450 Cysteinyl leukotriene receptor 1 is also a pyrimidinergic receptor and is expressed by human mast cells Elizabeth A. Mellor, Akiko Maekawa, K. Frank Austen, and Joshua A. Boyce PMCID: PMC35451 Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL-15 pathway Gustavo Baldassarre, Monica Fedele, Sabrina Battista, Andrea Vecchione, Andres J. P. Klein-Szanto, Massimo Santoro, Thomas A. Waldmann, Nazli Azimi, Carlo M. Croce, and Alfredo Fusco PMCID: PMC35452 Expression of error-prone polymerases in BL2 cells activated for Ig somatic hypermutation Vladimir Poltoratsky, Caroline J. Woo, Brigette Tippin, Alberto Martin, Myron F. Goodman, and Matthew D. Scharff PMCID: PMC35453 Medical Sciences From the Cover:
A low threshold level of expression of mutant-template telomerase RNA inhibits human tumor cell proliferation Moses M. Kim, Melissa A. Rivera, Inna L. Botchkina, Refaat Shalaby, Ann D. Thor, and Elizabeth H. Blackburn PMCID: PMC35454 Aromatase (Cyp19) expression is up-regulated by targeted disruption of Dax1 Zhen J. Wang, Baxter Jeffs, Masafumi Ito, John C. Achermann, Richard N. Yu, Dale B. Hales, and J. Larry Jameson PMCID: PMC35455 The type I BMP receptor BmprIB is essential for female reproductive function Soyun E. Yi, Philip S. LaPolt, Byeong S. Yoon, Jean Y.-C. Chen, John K. H. Lu, and Karen M. Lyons PMCID: PMC35456 C/EBP ![[var epsilon]](corehtml/pmc/pmcents/epsiv.gif) mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut) Arati Khanna-Gupta, Theresa Zibello, Hong Sun, Julie Lekstrom-Himes, and Nancy Berliner PMCID: PMC35457 Catalytic consumption of nitric oxide by 12/15- lipoxygenase: Inhibition of monocyte soluble guanylate cyclase activation Marcus J. Coffey, Rama Natarajan, Phillip H. Chumley, Barbara Coles, Pushpa-Rekha Thimmalapura, Mari Nowell, Hartmut Kühn, Malcolm J. Lewis, Bruce A. Freeman, and Valerie B. O'Donnell PMCID: PMC35458 From the Cover:
Short tandem repeat profiling provides an international reference standard for human cell lines John R. Masters, Jim A. Thomson, Bernadette Daly-Burns, Yvonne A. Reid, Wilhelm G. Dirks, Phil Packer, Lorraine H. Toji, Tadao Ohno, Hideyuki Tanabe, Colin F. Arlett, Lloyd R. Kelland, Maureen Harrison, Arvind Virmani, Timothy H. Ward, Karen L. Ayres, and Paul G. Debenham PMCID: PMC35459 Expression and functional significance of VE-cadherin in aggressive human melanoma cells: Role in vasculogenic mimicry Mary J. C. Hendrix, Elisabeth A. Seftor, Paul S. Meltzer, Lynn M. G. Gardner, Angela R. Hess, Dawn A. Kirschmann, Gina C. Schatteman, and Richard E. B. Seftor PMCID: PMC35460 Toward a new generation of vaccines: The anti-cytokine therapeutic vaccines Daniel Zagury, Arsene Burny, and Robert C. Gallo PMCID: PMC35461 Microbiology Protection from superoxide damage associated with an increased level of the YggX protein in Salmonella enterica Jeffrey Gralnick and Diana Downs PMCID: PMC35462 Reovirus reverse genetics: Incorporation of the CAT gene into the reovirus genome Michael R. Roner and Wolfgang K. Joklik PMCID: PMC35463 Neurobiology Modular organization of intrinsic connections associated with spectral tuning in cat auditory cortex Heather L. Read, Jeffery A. Winer, and Christoph E. Schreiner PMCID: PMC35464 Neurotensin-deficient mice show altered responses to antipsychotic drugs Paul R. Dobner, Jim Fadel, Nancy Deitemeyer, Robert E. Carraway, and Ariel Y. Deutch PMCID: PMC35465 GTP-binding protein βγ subunits mediate presynaptic calcium current inhibition by GABAB receptor Yoshinao Kajikawa, Naoto Saitoh, and Tomoyuki Takahashi PMCID: PMC35466 Excitatory versus inhibitory GABA as a divergence point in steroid-mediated sexual differentiation of the brain Anthony P. Auger, Tara S. Perrot-Sinal, and Margaret M. McCarthy PMCID: PMC35467 Three SNARE complexes cooperate to mediate membrane fusion Yuanyuan Hua and Richard H. Scheller PMCID: PMC35468 Different modes of hippocampal plasticity in response to estrogen in young and aged female rats Michelle M. Adams, Ravi A. Shah, William G. M. Janssen, and John H. Morrison PMCID: PMC35469 The affective component of pain in rodents: Direct evidence for a contribution of the anterior cingulate cortex Joshua P. Johansen, Howard L. Fields, and Barton H. Manning PMCID: PMC35470 Role of a pineal cAMP-operated arylalkylamine N-acetyltransferase/14-3-3-binding switch in melatonin synthesis Surajit Ganguly, Jonathan A. Gastel, Joan L. Weller, Christian Schwartz, Howard Jaffe, M. A. A. Namboodiri, Steven L. Coon, Alison B. Hickman, Mark Rollag, Tomas Obsil, Philippe Beauverger, Gilles Ferry, Jean A. Boutin, and David C. Klein PMCID: PMC35471 Light-induced phase-delay of the chicken pineal circadian clock is associated with the induction of cE4bp4, a potential transcriptional repressor of cPer2 gene Masao Doi, Yoshito Nakajima, Toshiyuki Okano, and Yoshitaka Fukada PMCID: PMC35472 The generation of oscillations in networks of electrically coupled cells Y. Loewenstein, Y. Yarom, and H. Sompolinsky PMCID: PMC35473 Brain activity evidence for recognition without recollection after early hippocampal damage E. Düzel, F. Vargha-Khadem, H. J. Heinze, and M. Mishkin PMCID: PMC35474 BDNF but not NT-4 is required for normal flexion reflex plasticity and function Paul A. Heppenstall and Gary R. Lewin PMCID: PMC35475 Pharmacology The synthesis, discovery, and development of a highly promising class of microtubule stabilization agents: Curative effects of desoxyepothilones B and F against human tumor xenografts in nude mice Ting-Chao Chou, Owen A. O'Connor, William P. Tong, Yongbiao Guan, Zui-Guo Zhang, Shawn J. Stachel, Chulbom Lee, and Samuel J. Danishefsky PMCID: PMC35476 Physiology Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na+] and pH but elevated viscosity Sujatha Jayaraman, Nam Soo Joo, Bruce Reitz, Jeffrey J. Wine, and A. S. Verkman PMCID: PMC35477 Electroretinogram analysis of relative spectral sensitivity in genetically identified dichromatic macaques Akitoshi Hanazawa, Akichika Mikami, Puti Sulistyo Angelika, Osamu Takenaka, Shunji Goto, Akishi Onishi, Satoshi Koike, Tetsuo Yamamori, Keichiro Kato, Aya Kondo, Bambang Suryobroto, Achmad Farajallah, and Hidehiko Komatsu PMCID: PMC35478 Adenosine diphosphate sugar pyrophosphatase prevents glycogen biosynthesis in Escherichia coli Beatriz Moreno-Bruna, Edurne Baroja-Fernández, Francisco José Muñoz, Ainara Bastarrica-Berasategui, Aitor Zandueta-Criado, Milagros Rodríguez-López, Iñigo Lasa, Takashi Akazawa, and Javier Pozueta-Romero PMCID: PMC35479 Plant Biology From the Cover:
The role of haustoria in sugar supply during infection of broad bean by the rust fungus Uromyces fabae Ralf T. Voegele, Christine Struck, Matthias Hahn, and Kurt Mendgen PMCID: PMC35480 Hydroperoxide lyase depletion in transgenic potato plants leads to an increase in aphid performance Guy Vancanneyt, Carlos Sanz, Theodora Farmaki, Manuel Paneque, Félix Ortego, Pedro Castañera, and Jose J. Sánchez-Serrano PMCID: PMC35481 Population Biology Prospective measurements of dehydroepiandrosterone sulfate in a cohort of elderly subjects: Relationship to gender, subjective health, smoking habits, and 10-year mortality Lise Mazat, Sylviane Lafont, Claudine Berr, Brigitte Debuire, Jean-François Tessier, Jean-François Dartigues, and Etienne-Emile Baulieu PMCID: PMC35482 Social Sciences Psychology Parallel detection of violations of color constancy David H. Foster, Sérgio M. C. Nascimento, Kinjiro Amano, Larry Arend, Karina J. Linnell, Juan Luis Nieves, Sabrina Plet, and Jeffrey S. Foster PMCID: PMC35483 Corrections Proc Natl Acad Sci U S A. 2001 July 3; 98(14): 8157. Published online 2001 June 26. PMCID: PMC55968 Corrects: Gunn-Guang Liou, et al. RNA degradosomes exist in vivo in
Escherichia coli as multicomponent complexes associated
with the cytoplasmic membrane via the N-terminal region of
ribonuclease E. Proc Natl Acad Sci U S A. 2001 January 2; 98(1): 63–68. Proc Natl Acad Sci U S A. 2001 July 3; 98(14): 8157. PMCID: PMC55969 Corrects: James Fallon, et al. In vivo induction of massive proliferation,
directed migration, and differentiation of neural cells in the
adult mammalian brain. Proc Natl Acad Sci U S A. 2000 December 19; 97(26): 14686–14691. |
