Facilitating oligonucleotide delivery: helping antisense deliver on its promise.

Plant genetic engineering may help with environmental cleanup.

Smaller fleas ... ad infinitum: therapeutic bacteriophage redux.

Thiocalsin: a thioredoxin-linked, substrate-specific protease dependent on calcium.

A serum-resistant cytofectin for cellular delivery of antisense oligodeoxynucleotides and plasmid DNA.

Mercuric ion reduction and resistance in transgenic Arabidopsis thaliana plants expressing a modified bacterial merA gene.

Long-circulating bacteriophage as antibacterial agents.

Cross-modulation by transforming growth factor beta in human tuberculosis: suppression of antigen-driven blastogenesis and interferon gamma production.

Sequence-specific arrest of primer extension on single-stranded DNA by an oligonucleotide-minor groove binder conjugate.

Chromosomal localization of the mammalian peptide-methionine sulfoxide reductase gene and its differential expression in various tissues.

Adenylyl cyclase inhibition and altered G protein subunit expression and ADP-ribosylation patterns in tissues and cells from Gi2 alpha-/-mice.

A unique role for the Rb protein in controlling E2F accumulation during cell growth and differentiation.

Protein-RNA interactions in the active center of transcription elongation complex.

X-ray absorption fine structure as a monitor of zinc coordination sites during oogenesis of Xenopus laevis.

Human myosin VIIA responsible for the Usher 1B syndrome: a predicted membrane-associated motor protein expressed in developing sensory epithelia.

SpoIIE governs the phosphorylation state of a protein regulating transcription factor sigma F during sporulation in Bacillus subtilis.

The C-terminal region of human angiogenin has a dual role in enzymatic activity.

Fos and Jun do not bend the AP-1 recognition site.

The dimer-dimer interaction surface of the replication terminator protein of Bacillus subtilis and termination of DNA replication.

The brain-specific activator p35 allows Cdk5 to escape inhibition by p27Kip1 in neurons.

Targeted gene disruption of Hsp70-2 results in failed meiosis, germ cell apoptosis, and male infertility.

Involvement of specific macrophage-lineage cells surrounding arterioles in barrier and scavenger function in brain cortex.

DUB-1, a deubiquitinating enzyme with growth-suppressing activity.

Chemical egg defense in a green lacewing (Ceraeochrysa smithi)

Positive selection and rates of evolution in immunodeficiency viruses from humans and chimpanzees.

A new high molecular weight immunoglobulin class from the carcharhine shark: implications for the properties of the primordial immunoglobulin.

4-Hydroxylation of estrogens as marker of human mammary tumors.

Distribution of endogenous type B and type D sheep retrovirus sequences in ungulates and other mammals.

Self-organized phase transitions in neural networks as a neural mechanism of information processing.

Inhibitors of the proteasome pathway interfere with induction of nitric oxide synthase in macrophages by blocking activation of transcription factor NF-kappa B.

Molecular characterization of a positively photoregulated nuclear gene for a chloroplast RNA polymerase sigma factor in Cyanidium caldarium.

Association of glycolate oxidation with photosynthetic electron transport in plant and algal chloroplasts.

Localization of the central rhythm generator involved in spontaneous consummatory licking in rats: functional ablation and electrical brain stimulation studies.

Crystal structure of the T state of allosteric yeast chorismate mutase and comparison with the R state.

Oxidation states of the manganese cluster during the flash-induced S-state cycle of the photosynthetic oxygen-evolving complex.

Why are some proteins structures so common?

Ecdysone-inducible gene expression in mammalian cells and transgenic mice.

Improved adenovirus packaging cell lines to support the growth of replication-defective gene-delivery vectors.

Markedly impaired humoral immune response in mice deficient in complement receptors 1 and 2.

N-methyl-D-aspartate receptor-induced proteolytic conversion of postsynaptic class C L-type calcium channels in hippocampal neurons.

The insect neuropeptide prothoracicotropic hormone is released with a daily rhythm: re-evaluation of its role in development.

Analysis of metabolic pathways by the growth of cells in the presence of organic solvents.

Peroxynitrite disables the tyrosine phosphorylation regulatory mechanism: Lymphocyte-specific tyrosine kinase fails to phosphorylate nitrated cdc2(6-20)NH2 peptide.

Transcription termination factor La is also an initiation factor for RNA polymerase III.

cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases.

Inhibition of apoptosis by overexpressing Bcl-2 enhances gene amplification by a mechanism independent of aphidicolin pretreatment.

Characterization of a second secreted IgE isoform and identification of an asymmetric pathway of IgE assembly.

Rel-deficient T cells exhibit defects in production of interleukin 3 and granulocyte-macrophage colony-stimulating factor.

Homing events in the gyrA gene of some mycobacteria.

Hyphal development in Neurospora crassa: involvement of a two-component histidine kinase.

A complexity measure for selective matching of signals by the brain.

Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat.

Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity.

Vestibular navigation directed by the slope of terrain.

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis.

Development of a bovine X chromosome linkage group and painting probes to assess cattle, sheep, and goat X chromosome segment homologies.

Identification of a protein that confers calcitonin gene-related peptide responsiveness to oocytes by using a cystic fibrosis transmembrane conductance regulator assay.

Fumonisins and Alternaria alternata lycopersici toxins: sphinganine analog mycotoxins induce apoptosis in monkey kidney cells.

Definition of the HLA-A29 peptide ligand motif allows prediction of potential T-cell epitopes from the retinal soluble antigen, a candidate autoantigen in birdshot retinopathy.

Logarithm of odds (lods) for linkage in complex inheritance.

Detection and localization of individual antibody-antigen recognition events by atomic force microscopy.

Production of transgenic dwarf surfclams, Mulinia lateralis, with pantropic retroviral vectors.

Transgenic barley expressing a protein-engineered, thermostable (1,3-1,4)-beta-glucanase during germination.

Islet amyloid formation associated with hyperglycemia in transgenic mice with pancreatic beta cell expression of human islet amyloid polypeptide.

Plasmodium falciparum erythrocyte membrane protein 1 is a parasitized erythrocyte receptor for adherence to CD36, thrombospondin, and intercellular adhesion molecule 1.

Variant antigens and endothelial receptor adhesion in Plasmodium falciparum.

Suppression of apoptosis by basement membrane requires three-dimensional tissue organization and withdrawal from the cell cycle.

Complexity of the erythroid transcription factor NF-E2 as revealed by gene targeting of the mouse p18 NF-E2 locus.

Human vitamin D receptor phosphorylation by casein kinase II at Ser-208 potentiates transcriptional activation.

Creation of drug-specific herpes simplex virus type 1 thymidine kinase mutants for gene therapy.

Twilight-zone and canopy shade induction of the Athb-2 homeobox gene in green plants.

cAMP inducibility of transcriptional repressor ICER in developing and mature human T lymphocytes.

Evidence that free polyunsaturated fatty acids modify Na+ channels by directly binding to the channel proteins.

Visualization of the vesicular acetylcholine transporter in cholinergic nerve terminals and its targeting to a specific population of small synaptic vesicles.

A functional Rev-erb alpha responsive element located in the human Rev-erb alpha promoter mediates a repressing activity.

Copy-up mutants of the plasmid RK2 replication initiation protein are defective in coupling RK2 replication origins.

Mimotope/anti-mimotope probing of structural relationships in platelet glycoprotein Ib alpha.

Functional protection of dystrophic mouse (mdx) muscles after adenovirus-mediated transfer of a dystrophin minigene.

N2 fixation in marine heterotrophic bacteria: dynamics of environmental and molecular regulation.

Defective dimerization of von Willebrand factor subunits due to a Cys-> Arg mutation in type IID von Willebrand disease.

Mutant cystic fibrosis transmembrane conductance regulator inhibits acidification and apoptosis in C127 cells: possible relevance to cystic fibrosis.

Fialuridine and its metabolites inhibit DNA polymerase gamma at sites of multiple adjacent analog incorporation, decrease mtDNA abundance, and cause mitochondrial structural defects in cultured hepatoblasts.

Protein-free cell culture on an artificial substrate with covalently immobilized insulin.

The virion glycoproteins of Ebola viruses are encoded in two reading frames and are expressed through transcriptional editing.

Stimulation of intrachromosomal homologous recombination in human cells by electroporation with site-specific endonucleases.

Interleukin 2 (IL-2) and interleukin 7 (IL-7) reciprocally induce IL-7 and IL-2 receptors on gamma delta T-cell receptor-positive intraepithelial lymphocytes.

The resource consumption principle: attention and memory in volumes of neural tissue.

Amino-terminal protein-protein interaction motif (POZ-domain) is responsible for activities of the promyelocytic leukemia zinc finger-retinoic acid receptor-alpha fusion protein.

Multidrug resistance proteins QacA and QacB from Staphylococcus aureus: membrane topology and identification of residues involved in substrate specificity.

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.

Rapid appearance and asymmetric distribution of glucose transporter SGTP4 at the apical surface of intramammalian-stage Schistosoma mansoni.

Mass spectrometric amino acid sequencing of a mixture of seed storage proteins (napin) from Brassica napus, products of a multigene family.

Human TOP3: a single-copy gene encoding DNA topoisomerase III.

Comparative interleukin (IL-2)/interferon IFN-gamma and IL-4/IL-10 responses during acute infection of macaques inoculated with attenuated nef-truncated or pathogenic SICmac251 virus.

Transcription of the human corticotropin-releasing hormone gene in NPLC cells is correlated with Z-DNA formation.

Interleukin 3 enhances cytotoxic T lymphocyte development and class I major histocompatibility complex "re-presentation" of exogenous antigen by tumor-infiltrating antigen-presenting cells.

The invariant system of coordinates of antibody molecules: prediction of the "standard" C alpha framework of VL and VH domains.

Neurotrophins stimulate phosphorylation of synapsin I by MAP kinase and regulate synapsin I-actin interactions.

P2X4: an ATP-activated ionotropic receptor cloned from rat brain.

Temporal events in cyclopean vision.

The wagon wheel illusion in movies and reality.

Progress toward chemical accuracy in the computer simulation of condensed phase reactions.

Vitamin C pharmacokinetics in healthy volunteers: evidence for a recommended dietary allowance.

The use of spreading depression waves for acute and long-term monitoring of the penumbra zone of focal ischemic damage in rats.

Identification of an inducible surface molecule specific to fusing macrophages

Mutation detection by highly sensitive methods indicates that p53 gene mutations in breast cancer can have important prognostic value