The National Institute of Neurological Disorders and Stroke Announces Effort to Promote Stroke Awareness in the Hispanic Community
Wednesday, Aug 8, 2007
The National Institute of Neurological Disorders and Stroke (NINDS), a component of the National Institutes of Health (NIH),
announced the launch of a new community education program, which broadens the Institute’s national stroke education campaign
"Know Stroke. Know the Signs. Act in Time." to promote stroke awareness among Hispanics in the United States.
NIH Study Finds MRI More Sensitive Than CT in Diagnosing Most Common Form of Acute StrokeFriday, Jan 26, 2007
Results from the most comprehensive study to compare two imaging techniques for the emergency diagnosis of suspected acute
stroke show that magnetic resonance imaging (MRI) can provide a more sensitive diagnosis than computed tomography (CT) for
acute ischemic stroke. The difference between MRI and CT was attributable to MRI’s superiority for detection of acute ischemic
stroke—the most common form of stroke, caused by a blood clot. The study was conducted by physicians at the National Institute
of Neurological Disorders and Stroke (NINDS), a part of the National Institutes of Health (NIH). Findings appear in the January
27, 2007 edition of The Lancet.
Gene Variants Linked to Risk of Stroke in Young WomenMonday, Nov 6, 2006
Specific variants of a gene called phosphodiesterase 4D (PDE4D) significantly increase the risk of stroke in women aged 15-49,
a new study shows. The risk is magnified in women who smoke cigarettes. The study is the first to identify a possible interaction
between this gene and an environmental factor in triggering stroke. The results help to show how the gene contributes to
stroke risk and may lead to new ways of preventing stroke.
Developing Tools to Detect Cognitive Impairment from Silent StrokesMonday, Nov 6, 2006
Scientists from the National Institute of Neurological Disorders and Stroke (NINDS) and the Canadian Stroke Network recently
wrapped up a workshop – the first of its kind – aimed at harmonizing clinical and research tools for assessing vascular cognitive
impairment (VCI), a common disability linked to stroke.
In Most Comprehensive Study Yet, Two-Week Regimen Helps Stroke Survivors Regain Arm ControlTuesday, Oct 31, 2006
In the largest, most comprehensive study of its kind to date, researchers supported by the National Institutes of Health (NIH)
showed clinical improvements out to one year when stroke survivors who had lost function in one arm were given a unique, two-week
rehabilitation regimen.
Researchers Identify Role of Protein Important for Stem Cell Growth; Study Leads to Recovery in Animal Model of StrokeWednesday, Aug 30, 2006
For the first time, researchers have found that a protein signal important in embryonic development promotes survival and
proliferation of stem cells. Stimulating receptors for this protein, called Notch, led to functional recovery in rats with
brain damage from stroke. The results suggest potential new ways of treating stroke and neurodegenerative diseases.
Double-Agent MMP-9: Timing is Everything in Stroke TreatmentThursday, Aug 3, 2006
In a surprise twist, researchers have learned that a type of enzyme that contributes to brain damage immediately after a stroke
also plays a role in brain remodeling and movement of neurons days after stroke. Understanding the secondary role for this
enzyme in healing stroke damage may lead to new treatments for stroke and offer a longer window of time for treatment.
Drug Prevents Brain Swelling After StrokeWednesday, Jun 14, 2006
A drug long used to treat diabetes significantly reduces brain swelling, neuron loss, and death after stroke in rats, researchers
have found. The finding may lead to improved ways of treating stroke and other disorders in humans.
Opening the Window of Opportunity: Neuregulin-1 Protects Neurons from Stroke Hours after the EventWednesday, Mar 8, 2006
Stroke is the third leading cause of death in adults in the United States. Currently, the only approved drug treatment for
acute stroke must be given within 3 hours from stroke onset. A recent study shows that a naturally occurring growth factor,
called neuregulin-1, can protect nerve cells and decrease inflammation in an animal model of stroke when administered as long
as 13 hours after the brain attack. This is the first study to show that neuregulin-1 can have a positive effect on the outcome
after stroke in animals and could lead to new drug treatments for people.
NINDS Launches Stroke Awareness Video for HispanicsTuesday, Aug 30, 2005
Each year, more than 700,000 Americans have a stroke. Stroke is the third leading cause of death and the leading cause of
long-term disability in the U.S. The disease also disproportionately affects Hispanics. According to the Centers for Disease
Control and Prevention, Hispanics 35-64 years old are 1.3 times more likely to have a stroke than whites in the same age group.
Today, the National Institute of Neurological Disorders and Stroke (NINDS) released a Spanish video designed to educate Hispanic
communities nationwide about stroke prevention and treatment.
Stroke Information for Seniors Added to the NIHSeniorHealth Web SiteTuesday, Aug 23, 2005
To help older adults learn more about the signs and symptoms of stroke and the need to act quickly, the National Institutes
of Health is adding four new topics on stroke to its NIHSeniorHealth web site: Act Quickly, Warnings Signs and Risk Factors,
What Happens during a Stroke, and Treatments and Research. The site features easy-to-read stroke information, developed by
the National Institute of Neurological Disorders and Stroke (NINDS), and may be found at www.nihseniorhealth.gov.
Ultrasound-aided Therapy Better Than Stroke Drug Alone, Trial FindsWednesday, Nov 17, 2004
Using ultrasound in combination with the drug t-PA can improve response to an ischemic stroke, according to a study involving
126 patients. This first-of-its-kind human trial compared the safety and efficacy of ultrasound and t-PA versus use of t-PA
alone. The trial was funded in part by the National Institute of Neurological Disorders and Stroke (NINDS), a component of
the National Institutes of Health. The finding appears in the November 18, 2004, issue of the New England Journal of Medicine.
Brain Imaging May Identify High Risk Stroke PatientsThursday, Oct 7, 2004
By using sophisticated magnetic resonance imaging (MRI) technology, researchers have been able to study early changes in the
blood-brain barrier (BBB), a semi-permeable membrane that surrounds and protects the brain, to predict a stroke patient's
outcome. This study showed that the patients who had disruption in the BBB were more likely to experience bleeding in the
brain and have a poor clinical outcome. The researchers say this technique could help identify patients who are most likely
to do the best with thrombolytic therapy, and to help clinicians offer additional therapies to those who might suffer complications.
Fact Sheet NINDS Sponsors Stroke Sunday to Call Attention to Stroke Rate in African AmericansTuesday, Oct 31, 2000
NINDS Deputy Director Audrey Penn and researchers from NINDS' Stroke Branch recently joined U.S. Surgeon General David Satcher
at a Rockville, Maryland, Baptist church for Stroke Sunday, a health education and stroke event co-sponsored by the American
Stroke Association (ASA) and the Black Commissioned Officers' Advisory Group of the U.S. Public Health Service (BCOAG). The
event brought attention to the major impact of stroke in the African American community and helped to inform church congregants
about reducing their stroke risks.
Fact Sheet Early Treatment Confirmed as Key to Stroke RecoveryThursday, Mar 4, 2004
A study in the March 6, 2004, issue of The Lancet confirms the benefits of getting stroke patients to the hospital quickly
for rapid thrombolytic treatment. The study provides the results of an extensive analysis of more than 2,700 stroke patients
in six controlled clinical trials who were randomized for treatment with thrombolytic t-PA or a placebo.
Fact Sheet Rewiring the Brain: A Natural Chemical Improves Motor Skills After StrokeMonday, Aug 12, 2002
A new study shows that a chemical naturally produced by the body helps improve motor skills after a stroke by stimulating
undamaged nerve fibers to grow new connections in the brain and spinal cord. Researchers say that infusions of this chemical,
called inosine, substantially improves brain function following strokes in rats. The study suggests a new potential for stroke
treatment amid ongoing research efforts.
Fact Sheet Another Reason to Avoid a Sugar High: Study Links High Blood Sugar to Mortality After StrokeFriday, Aug 23, 2002
Stroke has long been regarded as an untreatable condition with potentially devastating consequences. But in recent years,
new treatments have markedly improved patients' ability to recover from stroke, and researchers now have a new clue about
how to further improve stroke treatment.
Fact Sheet Preconditioning the brain may protect against strokeTuesday, Jan 13, 2004
A December 2003 news article on genetic changes to protect the brain against a second larger stroke, prepared by the National
Institute of Neurological Disorders and Stroke (NINDS).
Fact Sheet NIH Experts Say Few Eligible Stroke Patients Receive Treatments That Save Lives And Reduce DisabilityMonday, May 15, 2000
The National Institute of Neurological Disorders and Stroke, a component of the National Institutes of Health, said today
that few eligible stroke patients receive treatments that can significantly reduce disability and save lives.
New Tool Allows Early Prediction of Patient's Stroke OutcomeThursday, Jun 28, 2001
Scientists have developed a new tool that may help physicians predict, during the first several hours a stroke patient is
in the hospital, the degree of recovery the patient will eventually experience. The tool uses three factors for the accurate
prediction of stroke outcome: measurement of brain injury using magnetic resonance imaging (MRI); the patient's score on
the NIH stroke scale; and the time in hours from the onset of symptoms until the MRI brain scan is performed.
Fact Sheet Study Shows That Aspirin and Warfarin Are Equally Effective for Stroke PreventionWednesday, Nov 14, 2001
A study appearing in the November 15, 2001, issue of The New England Journal of Medicine shows that aspirin works as well
as warfarin in helping to prevent recurrent strokes in most patients. The Warfarin versus Aspirin Recurrent Stroke Study
(WARSS) was a 7-year double-blind, randomized clinical trial involving 2,206 patients at 48 participating centers—the largest
trial to date comparing aspirin to warfarin for recurrent stroke prevention. The study was sponsored by the National Institute
of Neurological Disorders and Stroke (NINDS).
Fact Sheet Estrogen Doesn't Prevent Second Strokes: Protective Effects of Hormone Replacement Therapy ChallengedThursday, Oct 25, 2001
Estrogen hormone replacement therapy does not reduce the risk of stroke or death in postmenopausal women who have already
had a stroke or a transient ischemic attack (TIA), according to a report from the first randomized, controlled clinical trial
of estrogen therapy for secondary prevention of cerebrovascular disease.
Fact Sheet New Stroke Treatment Likely to Decrease Health Care Costs and Increase Quality of LifeWednesday, Apr 22, 1998
BETHESDA, MD - Results from a new study show a greater than 90 percent probability that treating acute ischemic stroke patients
with the clot-busting drug t-PA could result in a substantial net cost savings to the health care system.
NINDS Symposium Produces National Plan for Rapid Stroke TreatmentFriday, Dec 13, 1996
For many of the 500,000 people who suffer a stroke each year, today will mark the beginning of a significant change in the
way they receive medical care.
Aspirin as Effective as Ticlopidine in African American Antiplatelet Stroke Prevention StudyTuesday, Jun 10, 2003
Results from the African American Antiplatelet Stroke Prevention Study (AAASPS), a large multicenter trial of 1,809 African
American stroke patients from over 60 sites in the United States, show that aspirin is as effective as ticlopidine for prevention
of a second stroke in this population. Originally scheduled to run until October 2003, the AAASPS was stopped in July 2002,
after analyses suggested that there was less than a 1% chance that ticlopidine would be shown to be superior to aspirin if
the study were carried to completion.
Fact Sheet NIH Announces Emergency Treatment for StrokeWednesday, Dec 13, 1995
A 5-year clinical trial has shown that treatment with the clot-dissolving drug t-PA is an effective emergency treatment for
acute ischemic stroke despite some risk from bleeding. The trial found that carefully selected stroke patients who received
t-PA treatment within 3 hours of their initial stroke symptoms were at least 30 percent more likely than untreated patients
to recover from their stroke with little or no disability after 3 months.
Most People Can't Identify Stroke SymptomsTuesday, Apr 21, 1998
A new study shows that most people can't identify even one symptom of stroke -- the number one cause of disability and the
third leading cause of death in this country. And the people most likely to suffer a stroke -- those over 75 years old --
are the least likely to know the symptoms of stroke and whether they're at risk for having a stroke.
Widely Used Therapy May Not Be Effective in Treatment of Acute StrokeTuesday, Apr 21, 1998
General use of anticlotting drugs, like low-molecular-weight (LMW) heparinoids, immediately after a stroke has little effect
in producing a good outcome or in preventing a second stroke in most patients, according to the results of a large clinical
trial published in the April 22, 1998, issue of The Journal of the American Medical Association.
Aspirin Shown Equal to Warfarin for Stroke Prevention in Some PatientsThursday, Mar 17, 1994
Results from a new study, funded by the National Institute of Neurological Disorders and Stroke (NINDS), will help physicians
select optimum treatment to prevent stroke in people with atrial fibrillation, a common type of irregular heartbeat. Published
in the March 19, 1994 issue of The Lancet*, the study shows that a daily adult aspirin can provide adequate stroke prevention
for many of the hundreds of thousands of people with atrial fibrillation. People with this condition have five times the risk
of stroke, and many are currently treated with warfarin, a drug that requires monthly blood tests and increases the risk of
serious bleeding.
Preventing Stroke: The Choice Between Aspirin and WarfarinTuesday, Apr 21, 1998
A new study outlines the criteria for identifying hundreds of thousands of Americans who have the most or least to gain from
the use of anticoagulants such as warfarin to prevent stroke. The study identifies certain patients with a common type of
irregular heartbeat called atrial fibrillation, and a low-risk for stroke who fare well by taking aspirin instead of warfarin
to prevent stroke.
Establishing Stroke Centers in Hospitals Would Reduce Deaths and Disabilities, Say Stroke Experts. First-Ever Recommendations
Published in June 21 Issue of JAMATuesday, Jun 20, 2000
BETHESDA, MD - A national stroke coalition today announced it is advocating for all hospitals to establish stroke centers
or other programs to reduce deaths and disabilities from stroke. The June 21, 2000, issue of the Journal of the American Medical
Association (JAMA) features the first-ever recommendations for hospital stroke centers, authored by members of the Brain Attack
Coalition, a group of professional, volunteer and government organizations dedicated to improving stroke treatment and prevention.
Fact Sheet Trial Stopped: Warfarin Therapy Reaffirmed for Stroke PreventionThursday, Sep 5, 1996
BETHESDA, MD. Warfarin, a standard blood-thinning drug used to prevent stroke, worked so well in certain high-risk patients
in a recent clinical trial that the study was halted early. Results of the Stroke Prevention in Atrial Fibrillation III (SPAF
III) trial, funded by the National Institute of Neurological Disorders and Stroke (NINDS), are published in the September
7 issue of The Lancet. The study demonstrated a 75 percent reduction in the risk of stroke for people with a common type
of irregular heartbeat called atrial fibrillation.
Stroke Recovery Rates Slower for African Americans: New Research Examines Reasons for Racial DisparitiesThursday, May 8, 2003
African Americans are more likely to suffer strokes and recover from them at a slower rate than whites, and these differences
are not simply the result of greater stroke severity. According to Ronnie D. Horner, Ph.D., program director at the National
Institute of Neurological Disorders and Stroke (NINDS), and leader of a recently published study, research has found that
African Americans who delay their post-stroke rehabilitation recover at a significantly slower rate than whites who experience
the same rehabilitation delay. Recovery rates are even lower among low-income African Americans.
Fact Sheet Vaccine Prevents Stroke in RatsThursday, Sep 5, 2002
A vaccine that interferes with inflammation inside blood vessels greatly reduces the frequency and severity of strokes in
spontaneously hypertensive, genetically stroke-prone rats, according to a new study from the NIH's National Institute of Neurological
Disorders and Stroke (NINDS). If the vaccine works in humans, it could prevent many of the strokes that occur each year.
Fact Sheet Increased Awareness of Stroke Symptoms Could Dramatically Reduce Stroke Disability - New NIH Public Education Campaign Says
Bystanders Can Play Key RoleTuesday, May 8, 2001
Only a fraction of stroke patients each year are getting to the hospital in time to receive a treatment that makes the difference
between disability and full recovery. Thousands more people could benefit from the treatment—a drug called tissue plasminogen
activator (t-PA)—but do not, often because they do not know the symptoms of stroke or do not get to the hospital within the
drug's 3-hour window of effectiveness. The National Institute of Neurological Disorders and Stroke (NINDS) is launching a
national public education campaign, 'Know Stroke: Know the Signs. Act in Time,' to help people overcome these barriers and
to get medical help in time.
Fact Sheet Federal Health Agencies Team Up with the American Heart Association to Advance War on Heart Disease and StrokeThursday, Feb 1, 2001
The Federal government and the American Heart Association—including its division the American Stroke Association—are joining
forces in the fight against heart disease and stroke, America's number one and number three killers, respectively.
Benefits of Surgery for Some Patients at High Risk for StrokeTuesday, Feb 26, 1991
Overwhelming evidence from an ongoing clinical trial shows that the surgical removal of fatty deposits from the the main artery
in the neck supplying blood to the brain is highly effective in reducing strokes for patients who have a severely narrowed
carotid artery and have previously had a stroke or symptoms of a stroke.
Story C. Landis, Ph.D., Named New Director of the National Institute of Neurological Disorders and StrokeWednesday, Aug 6, 2003
Elias Zerhouni, M.D., director of the National Institutes of Health (NIH), today announced the appointment of Story C. Landis,
Ph.D., as director of the National Institute of Neurological Disorders and Stroke (NINDS). Dr. Landis, who is currently the
Scientific Director of the NINDS intramural program, will begin her appointment on September 1, 2003.
Low Doses of Aspirin and Surgery Better for Stroke PreventionThursday, Jun 24, 1999
A new study shows that lower doses of aspirin given at the time of surgery work better than higher doses to prevent strokes.
The Aspirin and Carotid Endarterectomy (ACE) trial, sponsored by the National Institute of Neurological Disorders and Stroke
(NINDS), found that patients given 81 or 325 mg of aspirin a day for three days before and 3 months after carotid endarterectomy
(CE) surgery had less risk of stroke, heart attack, or death 30 days and 3 months following the surgery than did patients
given 650 or 1300 mg a day.
More Strokes May Be Prevented With Surgery, Study ShowsThursday, Feb 5, 1998
Investigators at more than 100 sites throughout the world have confirmed that surgery to remove fatty deposits from the arteries
that carry blood to the brain can significantly cut the risk of stroke in patients with moderate as well as severe blockage.
Fact Sheet Acute Stroke Therapy Moves AheadTuesday, Jun 18, 1996
Zach W. Hall, Ph.D., director of the National Institute of Neurological Disorders and Stroke (NINDS), applauded today's rapid
decision by the Food and Drug Administration (FDA) to approve t-PA for the emergency treatment of stroke. "The FDA action
means that we now have an approved emergency treatment for stroke, the leading cause of adult disability", Dr. Hall said.
"This is an exemplary demonstration of careful scientific investigation and of the power of partnership between industry,
academia and the Federal government."
Major Trial Confirms Benefit of Stroke Prevention SurgeryFriday, Sep 30, 1994
Officials at the National Institute of Neurological Disorders and Stroke (NINDS) announced that surgery can prevent stroke
in carefully selected individuals who have no outward sign of disease but are at risk for stroke from a severe narrowing of
a major artery in the neck. The NINDS brought to an early conclusion a 7-year clinical trial investigating the effectiveness
of a surgical procedure, called carotid endarterectomy, in reducing stroke in these individuals.