Table 4. Outcomes for the Recommendable Set of Efficient Screening Strategies
| Test, Age Begin–Age Stop, Intervala |
Outcomes per 1000 Persons (COL) |
Outcomes per 1000 Persons (Non-COLTests) |
Outcomes per 1000 Persons (LYG) |
Efficiency Ratiob |
Incidence Reduction, % |
Mortality Reduction, % |
| MISCAN |
|
|
|
|
|
|
| COL, 50–75, 10 |
4136 |
0 |
230 |
29.6 |
51.9 |
64.6 |
| Hemoccult SENSA, 50–75, 1 |
3350 |
9541 |
230 |
30.9 |
49.7 |
66.0 |
| FIT, 50–75, 1 |
2949 |
11773 |
227 |
25.9 |
47.2 |
64.6 |
| Hemoccult II, 50–75, 1 |
1982 |
16232 |
194 |
14.3 |
37.1 |
55.3 |
| FSIG, 50–75, 5 |
1911 |
4139 |
203 |
9.7 |
46.8 |
58.5 |
| FSIG + SENSA, 50–75, 5, 3 |
2870 |
5822 |
230 |
16.3 |
51.2 |
65.7 |
| SimCRC |
|
|
|
|
|
|
| COL, 50–75, 10 |
3756 |
0 |
271 |
34.7 |
80.6 |
84.4 |
| Hemoccult SENSA, 50–75, 1 |
2654 |
9573 |
259 |
22.9 |
73.2 |
81.2 |
| FIT, 50–75, 1 |
2295 |
11830 |
256 |
19.7 |
70.8 |
80.0 |
| Hemoccult II, 50–75, 1 |
1456 |
16239 |
218 |
9.6 |
56.6 |
69.0 |
| FSIG, 50–75, 5 |
995 |
4483 |
199 |
8.4 |
59.0 |
62.2 |
| FSIG + SENSA, 50–75, 5, 3 |
1655 |
11623 |
257 |
7.0 |
72.2 |
79.3 |
COL = colonoscopy; FIT = fecal immunochemical test; FSIG = flexible sigmoidoscopy; LYG = life-years gained compared with no screening;
MISCAN = Microsimulation Screening Analysis; SimCRC = Simulation Model of Colorectal Cancer.
a. Age and intervals expressed as years.
b. Efficiency ratio corresponds with ΔCOL/ΔLYG in the Appendix
Table and represents the relative burden per unit of benefit achieved.
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