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Found 42 studies with search of: "Neurofibroma"
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Rank Status Study
1 Recruiting Phase I Clinical Study of the Safety of Photodynamic Therapy (PDT) Using LS11 in Children With Plexiform Neurofibromas
Condition: Neurofibroma
Intervention: Drug: LS11
2 Suspended Study of PEG-Intron for Plexiform Neurofibromas
Condition: Plexiform Neurofibroma
Intervention: Drug: PEG-Intron
3 Recruiting Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1
Conditions: Neurofibromatosis Type 1;   Cutaneous Neurofibromas
Intervention: Drug: Ranibizumab
4 Recruiting Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1
Conditions: Dermal Neurofibromas;   Neurofibromatosis Type 1
Intervention:
5 Recruiting Topical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1
Conditions: Neurofibromatosis Type 1;   Cutaneous Neurofibromas
Intervention: Drug: Imiquimod 5% Cream
6 Active, not recruiting Study of Plexiform Neurofibromas in Neurofibromatosis Type 1
Conditions: Neurofibroma, Plexiform;   Neurofibromatosis Type I
Intervention:
7 Recruiting AZD2171 in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibroma and/or Neurofibroma Near the Spine
Conditions: Neurofibromatosis Type 1 (nf1);   Precancerous/Nonmalignant Condition
Intervention: Drug: cediranib maleate
8 Recruiting Fludeoxyglucose F 18 Positron Emission Tomography and Magnetic Resonance Perfusion Imaging in Patients With Neurofibromatosis 1 and Plexiform Neurofibroma
Conditions: Neurofibromatosis Type 1 (nf1);   Precancerous/Nonmalignant Condition
Interventions: Procedure: magnetic resonance imaging;   Procedure: positron emission tomography;   Procedure: radionuclide imaging;   Radiation: fludeoxyglucose F 18;   Radiation: gadopentetate dimeglumine
9 Completed Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas
Conditions: Neurofibromatosis Type 1 (nf1);   Precancerous/Nonmalignant Condition
Intervention: Drug: pirfenidone
10 Active, not recruiting Pirfenidone in Treating Young Patients With Neurofibromatosis Type I and Recurrent or Progressive Plexiform Neurofibromas
Conditions: Neurofibromatosis Type 1 (nf1);   Precancerous/Nonmalignant Condition
Intervention: Drug: pirfenidone
11 Recruiting Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas
Conditions: Neurofibromatosis Type 1 (nf1);   Precancerous/Nonmalignant Condition
Interventions: Drug: methotrexate;   Drug: vinblastine
12 Suspended Tipifarnib in Preventing Cancer in Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas
Conditions: Neurofibromatosis Type 1 (nf1);   Precancerous/Nonmalignant Condition;   Sarcoma
Interventions: Drug: tipifarnib;   Other: placebo
13 Recruiting Sirolimus in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas That Cannot Be Removed By Surgery
Conditions: Neurofibromatosis Type 1 (nf1);   Precancerous/Nonmalignant Condition
Intervention: Drug: sirolimus
14 Active, not recruiting Natural History Study of Plexiform Neurofibromas in Patients With Neurofibromatosis Type 1
Conditions: Neurofibromatosis Type 1 (nf1);   Precancerous/Nonmalignant Condition
Intervention: Procedure: magnetic resonance imaging
15 Recruiting PEG-Interferon Alfa-2b in Treating Young Patients With Unresectable Plexiform Neurofibromas Associated With Neurofibromatosis Type 1
Conditions: Neurofibromatosis Type 1 (nf1);   Precancerous/Nonmalignant Condition
Intervention: Biological: PEG-interferon alfa-2b
16 Recruiting Sorafenib in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas That Cannot Be Removed by Surgery
Conditions: Neurofibromatosis Type 1 (nf1);   Precancerous/Nonmalignant Condition
Intervention: Drug: sorafenib tosylate
17 Recruiting Childhood Cancer and Plexiform Neurofibroma Tissue Microarray for Molecular Target Screening and Clinical Drug Development
Condition: Cancer
Intervention:
18 Active, not recruiting PEG-Interferon Alfa-2b in Treating Young Patients With Plexiform Neurofibroma
Conditions: Neoplasm of Uncertain Malignant Potential;   Unspecified Childhood Solid Tumor, Protocol Specific
Intervention: Biological: PEG-interferon alfa-2a
19 Recruiting Medical Treatment of "High-Risk" Neurofibromas
Condition: Neurofibromatosis 1
Interventions: Drug: Peg-Interferon alpha-2b;   Drug: Celecoxib (Celebrex);   Drug: Temozolomide (temodar);   Drug: Vincristine Sulfate (Oncovin)
20 Recruiting A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas
Condition: Neurofibromatosis Type 1
Intervention: Drug: Sirolimus, Rapamycin

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