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Found 42 studies with search of: "Beta-Thalassemia"
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Rank Status Study
1 Completed Hydroxyurea to Treat Beta-Thalassemia (Cooley's Anemia)
Conditions: Beta Thalassemia;   Hemoglobinopathy
Intervention: Drug: Hydroxyurea
2 Completed Iron Balance Study of DFO and GT56-252 in Patients With Transfusional Iron Overload Secondary to Beta-Thalassemia
Condition: Beta-Thalassemia
Interventions: Drug: Deferitrin (GT56-252);   Drug: desferoxamine (DFO)
3 Active, not recruiting Cardiac T2* in Beta-Thalassemia Patients on Deferasirox Treatment
Conditions: Beta-Thalassemia;   Iron Overload
Intervention: Drug: Deferasirox
4 Completed Efficacy Study of the Use of Sequential DFP-DFO Versus DFP
Conditions: Beta-Thalassemia;   Thalassemia Major
Interventions: Drug: Deferiprone (DFP) and Deferoxamine (DFO);   Drug: Deferiprone (DFP)
5 Completed A Study of Long-Term Treatment With Deferasirox in Patients With Beta-Thalassemia and Transfusional Hemosiderosis
Conditions: Beta-Thalassemia;   Hemosiderosis
Intervention: Drug: deferasirox
6 Active, not recruiting Extension Study on Efficacy and Safety of Deferasirox Treatment in Patients With Beta-Thalassemia and Transfusional Hemosiderosis
Condition: Beta-Thalassemia Major
Intervention: Drug: ICL670; deferasirox
7 Recruiting Evaluating the Efficacy of Deferasirox in Transfusion Dependent Chronic Anaemias (Myelodysplastic Syndrome, Beta-Thalassaemia Patients) With Chronic Iron Overload
Conditions: Myelodysplastic Syndromes;   Beta-Thalassemia
Intervention: Drug: deferasirox
8 Recruiting Evaluating the Safety of G-CSF Mobilization in Individuals With Beta Thalassemia Major
Condition: Beta-Thalassemia
Intervention: Drug: Hydroxyurea
9 Active, not recruiting Combined Chelation Treatment With Deferiprone and Deferoxamine in Thalassemia Major
Condition: Beta-Thalassemia
Intervention: Drug: deferiprone
10 Completed Safety & Efficacy of ICL670 Vs. Deferoxamine in Beta-Thalassemia Patients With Iron Overload Due to Blood Transfusions
Condition: Beta-Thalassemia
Interventions: Drug: ICL670;   Drug: deferoxamine
11 Recruiting Phase 1/2 Study of HQK-1001 in Patients With Beta Thalassemia
Condition: Beta Thalassemia
Interventions: Drug: HQK-1001;   Drug: Placebo
12 Recruiting Genetic Factors Affecting the Severity of Beta Thalassemia
Condition: Beta Thalassemia
Intervention:
13 Completed Study of Deferasirox in Iron Overload From Beta-Thalassemia Unable to be Treated With Deferoxamine or Chronic Anemias
Conditions: Beta-Thalassemia;   Myelodysplastic Syndromes;   Fanconi Syndrome;   Anemia, Diamond-Blackfan;   Anemia, Aplastic
Intervention: Drug: Deferasirox
14 Completed Phase II Study of Arginine Butyrate With or Without Epoetin Alfa in Patients With Thalassemia Intermedia
Condition: Beta-Thalassemia
Interventions: Drug: arginine butyrate;   Drug: epoetin alfa
15 Recruiting Assess the Feasibility and Safety of Granulocyte Colony Stimulating Factor (GCSF) Mobilization of CD34+ Hematopoietic Progenitor Cells in Patients With Betathalassemia Major
Conditions: Beta Thalassemia Major;   Congenital Anemias
Intervention: Genetic: GCSF, Central venous line placement, Stem cell Collection (leukapheresis)
16 Completed Combination Therapy of Hydroxyurea With L-Carnitine and Magnesium Chloride in Thalassemia Intermedia
Condition: β-Thalassemia Intermedia
Interventions: Drug: hydroxyurea;   Drug: L-carnitine and hydroxyurea;   Drug: hydroxyurea and magnesium chloride;   Drug: hydroxyurea,L-carnitine and magnesium chloride
17 Completed Monitoring of Erythroid Lineage Specific Chimerism Following Allogeneic Hematopoietic Transplantation for Thalassemia Major
Condition: Thalassemia Major
Intervention:
18 Completed Thalassemia (Cooley's Anemia) Clinical Research Network (TCRN)
Conditions: Anemia, Cooley's;   Beta-Thalassemia;   Hematologic Diseases;   Thalassemia;   Osteoporosis;   Iron Overload;   Hypertension, Pulmonary
Interventions: Drug: Deferoxamine;   Drug: Deferiprone;   Drug: Arginine;   Drug: Sildenafil;   Drug: Decitabine
19 Active, not recruiting Iron Chelation Therapy With Deferasirox in β-Thalassemia Major Pediatric Patients With Transfusional Iron Overload
Condition: Transfusional Iron Overload in β-Thalassemia Major
Intervention: Drug: Deferasirox
20 Terminated Phase II Study of Azacitidine and Phenylbutyrate in Patients With Thalassemia Major
Condition: Thalassemia Major
Interventions: Drug: azacitidine;   Drug: phenylbutyrate

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