Hydroquinone (CASRN 123-31-9)
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0508
Hydroquinone; CASRN 123-31-9
Health assessment information on a chemical substance is included in IRIS only after a comprehensive review of chronic toxicity data by U.S. EPA health scientists from several Program Offices and the Office of Research and Development. The summaries presented in Sections I and II represent a consensus reached in the review process. Background information and explanations of the methods used to derive the values given in IRIS are provided in the Background Documents.
STATUS OF DATA FOR Hydroquinone
File First On-Line 10/01/1990
Category (section) |
Status |
Last Revised |
---|---|---|
Oral RfD Assessment (I.A.) | no data | |
Inhalation RfC Assessment (I.B.) | message | 10/01/1990 |
Carcinogenicity Assessment (II.) | no data |
_I. Chronic Health Hazard Assessments for Noncarcinogenic Effects
_I.A. Reference Dose for Chronic Oral Exposure (RfD)
Substance Name — Hydroquinone
CASRN — 123-31-9
Not available at this time.
_I.B. Reference Concentration for Chronic Inhalation Exposure (RfC)
Substance Name — Hydroquinone
CASRN — 123-31-9
The health effects data for hydroquinone were reviewed by the U.S. EPA RfD/RfC Work Group and determined to be inadequate for derivation of an inhalation RfC. The verification status of this chemical is currently not verifiable. For additional information on health effects of this chemical, interested parties are referred to the EPA documentation listed below.
U.S. EPA. 1987. Health and Environmental Effects Document for p-Hydroquinone Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. (Final Draft)
Agency Work Group Review — 08/23/1990
Screening-Level Literature Review Findings — A screening-level review conducted by an EPA contractor of the more recent toxicology literature pertinent to the RfC for Hydroquinone conducted in September 2002 did not identify any critical new studies. IRIS users who know of important new studies may provide that information to the IRIS Hotline at hotline.iris@epa.gov or (202)566-1676.
EPA Contacts:
Please contact the IRIS Hotline for all questions concerning this assessment or IRIS, in general, at (202)566-1676 (phone), (202)566-1749 (FAX) or hotline.iris@epa.gov (internet address).
_II. Carcinogenicity Assessment for Lifetime Exposure
Substance Name — Hydroquinone
CASRN — 123-31-9
This substance/agent has not undergone a complete evaluation and determination under US EPA's IRIS program for evidence of human carcinogenic potential.
_VI. Bibliography
Substance Name — Hydroquinone
CASRN — 123-31-9
Last Revised — 10/01/1990
_VI.A. Oral RfD References
None
_VI.B. Inhalation RfC References
U.S. EPA. 1987. Health and Environmental Effects Document for p-Hydroquinone Prepared by the Office of Health and Environmental Assessment, Environmental Criteria and Assessment Office, Cincinnati, OH for the Office of Solid Waste and Emergency Response, Washington, DC. (Final Draft)
_VI.C. Carcinogenicity Assessment References
None
_VII. Revision History
Substance Name — Hydroquinone
CASRN — 123-31-9
Date |
Section |
Description |
---|---|---|
10/01/1990 | I.B. | Inhalation RfC message on-line |
10/01/1990 | VI. | Bibliography on-line |
04/01/1997 | III., IV., V. | Drinking Water Health Advisories, EPA Regulatory Actions, and Supplementary Data were removed from IRIS on or before April 1997. IRIS users were directed to the appropriate EPA Program Offices for this information. |
12/03/2002 | I.B. | Screening-Level Literature Review Findings message has been added. |
_VIII. Synonyms
Substance Name — Hydroquinone
CASRN — 123-31-9
Last Revised — 10/01/1990
- ARCTUVIN
- 1,4-BENZENEDIOL
- P-BENZENEDIOL
- BENZOHYDROQUINONE
- BENZOQUINOL
- BLACK AND WHITE BLEACHING CREAM
- [COMPONENT OF] ARTRA
- [COMPONENT OF] SOLAQUIN
- DIAK 5
- DIHYDROQUINONE
- 1,4-DIHYDROXY-BENZEEN [DUTCH]
- 1,4-DIHYDROXYBENZEN [CZECH]
- DIHYDROXYBENZENE
- 1,4-DIHYDROXYBENZENE
- P-DIHYDROXYBENZENE
- 1,4-DIHYDROXY-BENZOL [GERMAN]
- 1,4-DIIDROBENZENE [ITALIAN]
- P-DIOXOBENZENE
- ELDOPAQUE
- ELDOQUIN
- HE 5
- HIDROQUINONA [SPANISH]
- HSDB 577
- HYDROCHINON [CZECH, POLISH]
- HYDROQUINOL
- HYDROQUINOLE
- HYDROQUINONE
- ALPHA-HYDROQUINONE
- P-HYDROQUINONE
- 4-HYDROXYPHENOL
- P-HYDROXYPHENOL
- IDROCHINONE [ITALIAN]
- NCI-C55834
- NSC 9247
- PHIAQUIN
- QUINOL (VAN)
- BETA-QUINOL
- TECQUINOL
- TENOX HQ
- TEQUINOL
- UANTOX HQ
- UN 2662
- USAF EK-356