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Found 16 studies with search of: "Gossypol"
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Rank Status Study
1 Active, not recruiting Gossypol (AT-101) and Temozolomide With or Without Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: R-(-)-gossypol acetic acid;   Drug: temozolomide;   Genetic: gene expression analysis;   Genetic: mutation analysis;   Genetic: protein expression analysis;   Other: laboratory biomarker analysis;   Other: pharmacological study;   Procedure: adjuvant therapy;   Radiation: radiation therapy
2 Completed Phase 2 Safety and Efficacy Study of AT-101 in Combination With Rituximab in Patients With Chronic Lymphocytic Leukemia
Condition: Chronic Lymphocytic Leukemia
Intervention: Drug: AT-101
3 Completed Safety & Efficacy Study of AT-101 in Combination w/ Rituximab in Previously Untreated Grade I-II Follicular Non-Hodgkin's Lymphoma
Condition: Follicular Lymphoma
Interventions: Drug: AT-101;   Drug: Rituximab
4 Active, not recruiting Safety and Efficacy Study of AT-101 in Combination With Docetaxel and Prednisone in Men With Hormone Refractory Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: AT-101;   Drug: Docetaxel;   Drug: Prednisone
5 Completed Study of AT-101 in Combination With Topotecan in Relapsed/Refractory Small Cell Lung Cancer
Condition: Small Cell Lung Cancer
Intervention: Drug: AT-101
6 Active, not recruiting Gossypol in Treating Patients With Progressive or Recurrent Glioblastoma Multiforme
Condition: Brain and Central Nervous System Tumors
Interventions: Drug: R-(-)-gossypol acetic acid;   Genetic: protein expression analysis;   Other: immunoenzyme technique;   Other: laboratory biomarker analysis
7 Recruiting Gossypol Acetic Acid in Treating Patients With Recurrent, Metastatic, or Primary Adrenocortical Cancer That Cannot Be Removed By Surgery
Condition: Adrenocortical Carcinoma
Intervention: Drug: R-(-)-gossypol acetic acid
8 Not yet recruiting Gossypol, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery
Conditions: Lymphoma;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: R-(-)-gossypol acetic acid;   Drug: carboplatin;   Drug: paclitaxel;   Other: laboratory biomarker analysis;   Other: liquid chromatography;   Other: mass spectrometry;   Other: pharmacological study
9 Recruiting Gossypol, Cisplatin, and Etoposide in Treating Patients With Advanced Solid Tumors or Extensive Stage Small Cell Lung Cancer
Conditions: Lung Cancer;   Unspecified Adult Solid Tumor, Protocol Specific
Interventions: Drug: R-(-)-gossypol acetic acid;   Drug: cisplatin;   Drug: etoposide
10 Active, not recruiting A Randomized Phase 2 Study of AT-101 in Combination With Docetaxel in Relapsed/Refractory Non-Small Cell Lung Cancer
Condition: Non-Small Cell Lung Cancer
Interventions: Drug: AT-101 and docetaxel;   Drug: placebo and docetaxel
11 Recruiting Gossypol in Treating Patients With Recurrent Extensive-Stage Small Cell Lung Cancer
Condition: Lung Cancer
Interventions: Drug: R-(-)-gossypol acetic acid;   Genetic: protein expression analysis;   Genetic: western blotting;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis;   Other: pharmacological study
12 Suspended Gossypol and Androgen Ablation Therapy in Treating Patients With Newly Diagnosed Metastatic Prostate Cancer
Condition: Prostate Cancer
Interventions: Drug: R-(-)-gossypol acetic acid;   Drug: bicalutamide;   Drug: releasing hormone agonist therapy;   Genetic: protein expression analysis;   Genetic: western blotting;   Other: immunohistochemistry staining method;   Other: laboratory biomarker analysis
13 Completed Phase II Safety and Efficacy Study of Single-Agent AT-101 in Patients With Relapsed or Refractory B-Cell Malignancies
Conditions: Follicular Lymphoma;   Diffuse Large Cell Lymphoma;   Mantle Cell Lymphoma;   Small Lymphocytic Lymphoma;   Chronic Lymphocytic Leukemia
Intervention: Drug: AT-101
14 Recruiting An Open-Label, Single-Center, Phase 1/ 2 Study of Chemoradiotherapy and AT-101 in Patients With Locally Advanced Esophageal or Gastroesophageal Junction Cancer
Condition: Locally Advanced Esophageal or GE Junction Cancer
Intervention: Drug: AT-101
15 Active, not recruiting A Study Comparing AT-101 in Combination With Docetaxel and Prednisone Versus Docetaxel and Prednisone in Men With Chemotherapy-Naïve Metastatic Hormone Refractory Prostate Cancer (HRPC)
Condition: Hormone Refractory Prostate Cancer
Interventions: Drug: AT-101, prednisone and docetaxel;   Drug: placebo, prednisone and docetaxel
16 Completed A Study of Single-Agent AT-101 in Men With Hormone Refractory Prostate Cancer
Condition: Hormone Refractory Prostate Cancer
Intervention: Drug: AT-101

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