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Found 245 studies with search of: "Topotecan"
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Rank Status Study
1 Recruiting A Phase 1b Study of AMG 386 in Combination With Either Pegylated Liposomal Doxorubicin or Topotecan in Subjects With Advanced Recurrent Epithelial Ovarian Cancer
Conditions: Cancer;   Carcinoma;   Fallopian Tube Cancer;   Gynecological Malignancies;   Metastases;   Oncology;   Ovarian Cancer;   Solid Tumors;   Tumors
Interventions: Drug: Part 2, Cohort A: AMG 386 MTD Part 1 + Liposomal doxorubicin;   Drug: B1: AMG 386 10 mg/kg + Topotecan;   Drug: B2: AMG 386 3mg/kg + Topotecan;   Drug: A1: AMG 386 10 mg/kg + Liposomal doxorubicin;   Drug: A2: AMG 386 3mg/kg + Liposomal doxorubicin;   Drug: Part 2, Cohort B: AMG 386 MTD part 1 + Topotecan
2 Recruiting Phase 1 Intrathecal Topotecan for Neoplastic Meningitis
Condition: Neoplastic Meningitis
Interventions: Drug: Topotecan;   Drug: Topotecan;   Drug: Topotecan
3 Recruiting Study of Temsirolimus, Topotecan, and Bortezomib
Condition: Advanced Cancer
Interventions: Drug: Torisel (Temsirolimus);   Drug: Hycamtin (Topotecan);   Drug: Velcade (Bortezomib)
4 Recruiting Ph I Trial of Oral Topotecan + Temozolomide in Treatment of Pts w Malignant Gliomas
Conditions: Glioblastoma;   Gliosarcoma;   Anaplastic Astrocytoma
Intervention: Drug: Temodar and Topotecan
5 Withdrawn A Phase I Study Of Oral Topotecan And Lapatinib In Subjects With Advanced Solid Tumors
Condition: Advanced Solid Tumors
Intervention: Drug: oral topotecan (SK&F-104864); lapatinib (GW572016)
6 Completed Intravenous Weekly Topotecan In Subjects With Recurrent Or Persistent Endometrial Cancer
Condition: Endometrial Cancer
Intervention: Drug: topotecan
7 Completed Oral Topotecan Versus Intravenous Docetaxel In Pretreated, Advanced Non-Small Cell Lung Cancer
Condition: Non-Small-Cell Lung Cancer
Intervention: Drug: topotecan
8 Completed Active Symptom Control Alone Or In Combination With Oral Topotecan In Patients With Relapsed Resistant Small Cell Lung Cancer
Condition: Small Cell Lung Cancer
Intervention: Drug: topotecan
9 Completed Comparison of IV Topotecan/Docetaxel to Docetaxel Alone in Second-Line Stage IIIB/IV Non-Small Cell Lung Cancer
Condition: Non-Small-Cell Lung Cancer
Interventions: Drug: Topotecan/Docetaxel combination;   Drug: Docetaxel
10 Active, not recruiting Topotecan Weekly Versus Topotecan Day 1-5 in Patient With Platin-Resistant Ovarian Cancer
Condition: Ovarian Cancer
Interventions: Drug: Topotecan;   Drug: Topotecan
11 Recruiting Topotecan, Ifosfamide and Carboplatin in Children and Young Adults With Solid Tumors
Condition: Solid Tumors
Interventions: Drug: Topotecan;   Drug: Ifosfamide;   Drug: Carboplatin
12 Completed Study to Assess the Safety and Tolerability of a PARP Inhibitor in Combination With Topotecan
Condition: Malignant Solid Tumors
Interventions: Drug: KU-0059436 (AZD2281)(PARP inhibitor);   Drug: Topotecan
13 Active, not recruiting Phase I, Dosage-Finding and PK Study of IV Topotecan and Erlotinib With Refractory Solid Tumors
Condition: Metastatic Solid Tumor
Interventions: Drug: Topotecan;   Drug: Erlotinib
14 Completed A Study To Determine If Two Different Versions Of Topotecan Have The Same Potency In Patients With Advanced Solid Tumors
Condition: Tumor
Intervention: Drug: topotecan
15 Terminated Efficacy of Topotecan and Lapatinib in Early Recurrent Ovarian or Peritoneal Cancer
Conditions: Cancer;   Ovarian;   Relapse;   Chemotherapy
Interventions: Drug: TOPOTECAN;   Drug: LAPATINIB
16 Recruiting Oral Topotecan to Treat Recurrent or Persistent Solid Tumors
Condition: Tumors
Intervention: Drug: Oral Topotecan
17 Completed Study of Adjuvant Topotecan and Cisplatin With Concurrent Radiation Therapy for Advanced Cervical Cancer
Condition: Cervical Cancer
Interventions: Drug: Topotecan;   Drug: Cisplatin
18 Recruiting Genomic Directed Salvage Chemotherapy With Either Liposomal Doxorubicin Or Topotecan
Condition: Ovarian Cancer
Interventions: Drug: Liposomal Doxorubicin;   Drug: Topotecan
19 Not yet recruiting Study of Oral Topotecan With Bevacizumab for Recurrent Small Cell Lung Cancer
Condition: Recurrent Small-Cell Lung Cancer (SCLC)
Intervention: Drug: Oral Hycamtin (topotecan) Capsules + IV Avastin (bevacizumab)
20 Recruiting Hycamtin Plus Carboplatin Versus Established Regimens for the Treatment of Ovarian Cancer Relapse
Condition: Ovarian Cancer
Intervention: Drug: Topotecan

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