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Found 11 studies with search of: "Protherics" [Exact]
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1 Recruiting Open-Label Leucovorin Pharmacokinetic Study in Patients Receiving High Dose Methotrexate With or Without Voraxaze
Conditions: Osteosarcoma;   Leukemia;   Lymphoma
Interventions: Drug: glucarpidase, high-dose methotrexate, leucovorin;   Drug: high-dose methotrexate, leucovorin
2 Active, not recruiting Safety and Efficacy Study of Angiotensin Therapeutic Vaccine in Subjects With Mild to Moderate Hypertension
Conditions: Hypertension;   Cardiovascular Disease
Interventions: Biological: Angiotensin Therapeutic Vaccine plus CoVaccine HT™ adjuvant;   Biological: CoVaccine HT™ adjuvant
3 Terminated High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma
Condition: Osteosarcoma
Interventions: Drug: glucarpidase;   Drug: leucovorin
4 Recruiting Safety and Tolerability Open Label Dose Escalation Study of Acadesine in B-CLL Patients
Condition: Leukemia, B-Cell, Chronic
Intervention: Drug: Acadesine
5 Recruiting Efficacy and Safety of OncoGel™ Added to Chemotherapy and Radiation Before Surgery in Subjects With Esophageal Cancer
Conditions: Esophageal Cancer;   Adenocarcinoma of the Esophagus;   Squamous Cell Carcinoma
Interventions: Drug: OncoGel (Paclitaxel gel);   Drug: cisplatin;   Drug: 5-FU;   Radiation: radiation therapy;   Procedure: esophageal resection
6 Completed Efficacy Study of Digibind for Treatment of Severe Preeclampsia
Condition: Pre-Eclampsia
Interventions: Drug: Anti-digoxin antibody (FAB fragment);   Drug: Digoxin Immune Fab ovine;   Drug: 0.9% sodium chloride
7 Available Treatment Protocol of Voraxaze for Patients Experiencing or at Risk of Methotrexate Toxicity
Condition: Neoplasms
Intervention: Drug: Voraxaze (glucarpidase)
8 Terminated A Phase 1 / 2 Dose Escalation Study of Locally-Administered OncoGel™ in Subjects With Recurrent Glioma
Conditions: Glioblastoma Multiforme;   Brain Neoplasms
Intervention: Drug: OncoGel (ReGel/Paclitaxel)
9 Recruiting Study of Anti-Tumour Effects and Safety of Prolarix™ in Hepatocellular Carcinoma
Condition: Hepatocellular Carcinoma
Intervention: Drug: Prolarix (tretazicar co-administered with caricotamide)
10 Completed Study of Glucarpidase (CPG2) for the Management of Patients With Delayed Methotrexate Clearance
Condition: Neoplasms
Intervention: Drug: glucarpidase (50 Units/kg)
11 Completed Voraxaze for Delayed Methotrexate Clearance
Conditions: Hematologic Malignancy;   Solid Tumor
Interventions: Drug: Voraxaze;   Drug: Placebo

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