Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards

This study is currently recruiting participants.

Verified by Ludwig-Maximilians - University of Munich, October 2007

First Received: February 1, 2007 Last Updated: November 1, 2007 History of Changes

Sponsored by:	Ludwig-Maximilians - University of Munich
Information provided by:	Ludwig-Maximilians - University of Munich
ClinicalTrials.gov Identifier:	NCT00431483

Purpose

The purpose of this study is to establish the impact of a pharmacist's recommendations regarding choice, dosing and duration of antibiotic therapy on quality and cost of antibiotic treatment on surgical wards.

Condition	Intervention
Bacterial Infections	Behavioral: pharmaceutical consulting

MedlinePlus related topics: Antibiotics Bacterial Infections Surgery

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Supportive Care, Non-Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Official Title:	Clinical and Economic Impact of Interventions by a Clinical Pharmacist on Antibiotic Use on Surgical Wards

Further study details as provided by Ludwig-Maximilians - University of Munich:

Primary Outcome Measures:

overall expenditure for antibiotics during study period [ Time Frame: October 2008 ]
number of inappropriately prescribed antibiotics [ Time Frame: October 2008 ]

Estimated Enrollment:	600
Study Start Date:	February 2007
Estimated Study Completion Date:	March 2008

Intervention Details:

to measure if information and advice by a pharmacist has an impact on quality and quantity of prescribed antibacterials

Detailed Description:

Inappropriate or incorrect use of antibacterials exerts selection pressure on pathogens potentiating emergence of resistance, puts patients at risk for unnecessary adverse drug reactions and potentially prolongs the length of stay in hospital thus increasing healthcare costs.

In an effort to improve the quality of antibiotic drug therapy on surgical wards of a large university hospital, specific consulting by a clinical pharmacist was established. The objective of this study is to assess the impact of pharmaceutical consulting on the quality and costs of antibiotic use in surgical wards.

Comparison:

Within a control period the current pattern of antibiotic use is monitored. During the intervention period, the impact of the interventions made by the clinical pharmacist on antibiotic use is examined. One ward serves as a parallel control group; no intervention is being made on this ward throughout this study.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

female and male patients receiving antibiotics for a proven or suspected infection on designated surgical wards

Exclusion Criteria:

patients under 18
patients unable or unwilling to consent to their data being evaluated
patients receiving antibiotics perioperatively as prophylaxis
patients receiving antibiotics for less than 48hrs

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00431483

Contacts

Contact: Alexandra Weber, M Pharm

+49-89-7095-2467

alexandra.weber@med.uni-muenchen.de

Locations

Germany, Bavaria
Luwig Maximilians University - Klinikum Grosshadern	Recruiting
Munich, Bavaria, Germany, 81377
Contact: Alexandra Weber, MPharm 089-7095 ext 2467 alexandra.weber@med.uni-muenchen.de

Sponsors and Collaborators

Ludwig-Maximilians - University of Munich

Investigators

Study Director:

Karl-Walter Jauch, Prof. Dr.

Klinikum Grosshadern

More Information

No publications provided

Study ID Numbers:	AW2007
Study First Received:	February 1, 2007
Last Updated:	November 1, 2007
ClinicalTrials.gov Identifier:	NCT00431483 History of Changes
Health Authority:	Germany: Ethics Commission

Keywords provided by Ludwig-Maximilians - University of Munich:

antibacterial agents
surgery
pharmacist
economics, pharmaceutical

Study placed in the following topic categories:

Bacterial Infections
Anti-Bacterial Agents

Additional relevant MeSH terms:

Bacterial Infections
Anti-Infective Agents
Anti-Bacterial Agents

Therapeutic Uses
Infection
Pharmacologic Actions

ClinicalTrials.gov processed this record on May 07, 2009