Inclusion Criteria

Concurrent Medication:

Allowed:

• Aerosolized pentamidine.

Patients must have the following:

• Seropositive for HIV-1 (ELISA assay) confirmed by Western blot.
• HIV-1 p24 antigen must be detected in supernatant fluids from co-cultures of patients' peripheral blood monocytes (PBMC) on two separate occasions.
• Voluntarily sign consent.
• Patients with HIV "wasting syndrome" are allowed.

Prior Medication:

Allowed:

• Aerosolized pentamidine.

Exclusion Criteria

Co-existing Condition:

Patients with the following are excluded:

• AIDS as defined by the CDC.
• Significant hepatic disease.
• Thrombocytopenia.
• Hypersensitivity to thymopentin.
• Hemophilia A or B or other hematologic disorders requiring current or previous administration of blood products.
• Abnormal chest x-ray (indicative of active disease (opportunistic infection)) within 30 days prior to study entry.

Patients with the following are excluded:

• AIDS as defined by the CDC.
• Significant hepatic disease.
• Thrombocytopenia.
• Hypersensitivity to thymopentin.
• Hemophilia A or B or other hematologic disorders requiring current or previous administration of blood products.
• Abnormal chest x-ray (indicative of active disease (opportunistic infection)) within 30 days prior to study entry.

Prior Medication:

Excluded within 30 days of study entry:

• Immunomodulatory or experimental therapy.
• Excluded within 90 days of study entry:
• Zidovudine (AZT).

Intravenous drug abuse.