Inclusion Criteria:

• Subject has to:

  1. be Caucasian male
  2. be aged between 18-55 years, inclusive
  3. have a body-mass index (BMI): ≥ 19 kg/m² and ≤ 27 kg/m²
  4. be considered to be healthy on the basis of extensive pre-study eligibility assessment
  5. be a non-smoker or an ex-smoker for at least 1 month
  6. be willing and capable to confirm written consent to enrolment after ample information has been provided

Exclusion Criteria:

• Subjects cannot be included if they match any of the following exclusion criteria:

  1. existence of any surgical or medical condition which might interfere with the absorption, distribution, metabolism or excretion of the drug, i.e.

     impaired renal or hepatic function, diabetes mellitus, cardiovascular abnormalities, chronic symptoms of pronounced constipation or diarrhoea or conditions associated with total or partial obstruction of the urinary tract.

  2. presence of active gastric/duodenal ulcer or gastrointestinal bleeding, of enteritis like Crohn's disease or ulcerative colitis, clinically confirmed coronary heart disease and/or cerebrovascular disease, cardiac insufficiency (NYHA II-IV), severe liver insufficiency, or severe renal insufficiency
  3. history of relevant CNS and/or psychiatric disorders and/or currently treated CNS and/or psychiatric disorders
  4. pathological ECG (12 standard leads)
  5. known allergic reactions to the active ingredient used, substituted benzimidazole or to other constituents of the pharmaceutical preparations
  6. subjects with severe allergies or multiple drug allergies
  7. positive results of the urine drug screen
  8. laboratory values out of normal range unless the deviation from normal is judged as not relevant for the study by the investigator
  9. positive anti-HIV-test, HBs-AG-test or anti-HCV-test
  10. lactose or fructose intolerance
  11. glucose-galactose malabsorption
  12. history of or current drug or alcohol dependence
  13. regular intake of alcoholic food or beverages of ≥ 40 g pure ethanol per day
  14. subjects who are on a diet which could affect the pharmacokinetics of the drug
  15. regular intake of caffeine containing food or beverages of ≥ 500 mg caffeine per day
  16. blood donation or other blood loss of more than 400 ml within the last two months prior to the start of the study
  17. participation in a clinical trial during the last two months prior to the start of the study
  18. subjects, who report a frequent occurrence of migraine attacks
  19. regular treatment with any systemically available medication (except hormonal replacement therapy e.g. L-thyroxine) within 14 days prior to the first administration of the study medication
  20. subjects suspected or known not to follow instructions