Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsored by: |
Hadassah Medical Organization |
---|---|
Information provided by: | Hadassah Medical Organization |
ClinicalTrials.gov Identifier: | NCT00353210 |
Human embryonic stem cells (hESCs) are isolated from the early human embryo and have the capability to proliferate indefinitely in culture and to develop into nearly every cell of the human body. hESC are important for studying developmental biology and for cell replacement therapies for the treatment of degenerative human diseases. An additional use for embryonic stem cells would be for the in vitro study of diseases. hESC lines derived from embryos diagnosed as abnormal by PGD testing would afford such models for study. Because embryos tested by PGD and found to be abnormal would only under rare circumstances be transferred to the uterus of a woman (and in most cases would be discarded), the derivation of new hESC lines from these embryos would provide a viable less ethically-objectionable source of cells with which to study the mechanisms of differentiation and developmental biology.
Condition |
---|
Infertility |
Study Type: | Observational |
Official Title: | The Derivation of Human Embryonic Stem Cell Lines From PGD Embryos |
Retain serum samples of embryo donors.
Estimated Enrollment: | 30 |
Study Start Date: | April 2004 |
Estimated Study Completion Date: | October 2009 |
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
Embryo donors of embryos that have undergone PGD analysis after IVF which the donors have no intention of using for family-building purposes.
Inclusion Criteria:
Exclusion Criteria:
Contact: Benjamin E. Reubinoff, M.D. PhD. | 011-972-2-677-7111 ext 74569 | reubinof@md.huji.ac.il |
Contact: Shelly E. Tannenbaum, B.S. | 011-972-2-677-7111 ext 77947 | stannenbaum@hadassah.org.il |
Israel | |
Hadassah Medical Organization | Recruiting |
Jerusalem, Israel, 91120 | |
Contact: Arik Tzukert, DMD 011-972-2-677-7111 ext 76095 arik@hadassah.org.il | |
Contact: Hadas Lemberg, PhD 011-972-2-677-7111 ext 77572 lhadas@hadassah.org.il | |
Principal Investigator: Benjamin E. Reubinoff, M.D. PhD. |
Principal Investigator: | Benjamin E. Reubinoff, M.D. PhD. | Hadassah Medical Organization |
Responsible Party: | Hadassah Medical Organization ( Professor Benjamin Reubinoff ) |
Study ID Numbers: | 24-23.04.04-HMO-CTIL |
Study First Received: | July 16, 2006 |
Last Updated: | May 5, 2009 |
ClinicalTrials.gov Identifier: | NCT00353210 History of Changes |
Health Authority: | Israel: Israeli Health Ministry Pharmaceutical Administration |
IVF embryos research donation |
surplus stem cells abnormal embryo screening |
Genital Diseases, Female Infertility Genital Diseases, Male |
Genital Diseases, Female Infertility Genital Diseases, Male |