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Sponsored by: |
University Hospital, Grenoble |
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Information provided by: | University Hospital, Grenoble |
ClinicalTrials.gov Identifier: | NCT00710099 |
Iontophoresis is a employed to facilitate drug absorption without systemic effect. This study investigates cutaneous microcirculation when we associate sildenafil per os with SNP via iontophoresis.
Condition | Intervention |
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Healthy |
Drug: sildenafil Drug: nitroprussiate iontophoresis |
Study Type: | Interventional |
Study Design: | Treatment, Non-Randomized, Open Label, Dose Comparison, Single Group Assignment |
Official Title: | Effect of Oral Sildenafil With Digital Therapeutic Iontophoresis of Sodium Nitroprussiate on Cutaneous Blood Flow in Healthy Volunteers |
Estimated Enrollment: | 20 |
Study Start Date: | July 2008 |
Estimated Study Completion Date: | July 2009 |
Estimated Primary Completion Date: | June 2009 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
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1: Experimental |
Drug: sildenafil
systemic absorption of sildenafil
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2: Active Comparator
SNP iontophoresis
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Drug: nitroprussiate iontophoresis
nitroprussiate iontophoresis
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The main outcome is the proof of concept of effect of systemic absorption sildenafil on cutaneous microcirculation associated with SNP iontophoresis.
Ages Eligible for Study: | 18 Years and older |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Contact: Jean-Luc CRACOWSKI, MD | +33(0)476769260 | JLCracowski@chu-grenoble.fr |
France, Isere | |
Clinical Researsh Centre | Recruiting |
Grenoble, Isere, France, 38043 | |
Contact: Jean-Luc Cracowski, MD +330476769260 | |
Principal Investigator: Jean-Luc Cracowski, MD | |
Sub-Investigator: Blaise Sophie, MD |
Principal Investigator: | Jean-Luc CRACOWSKI, MD | Institut National de la Santé Et de la Recherche Médicale, France |
Responsible Party: | Clinical research management ( M Eric Svhan ) |
Study ID Numbers: | DCIC/08/08 |
Study First Received: | July 2, 2008 |
Last Updated: | July 3, 2008 |
ClinicalTrials.gov Identifier: | NCT00710099 History of Changes |
Health Authority: | France: Afssaps - French Health Products Safety Agency |
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