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Factors Associated With Coronary Heart Disease in African Americans in the Jackson Heart Study
This study has been completed.
Sponsored by: National Heart, Lung, and Blood Institute (NHLBI)
Information provided by: National Heart, Lung, and Blood Institute (NHLBI)
ClinicalTrials.gov Identifier: NCT00415415
  Purpose

Coronary heart disease (CHD) is the leading cause of deaths that are related to cardiovascular disease in the United States, and Mississippi's CHD mortality rate is the highest in the nation. This study will examine data from the Jackson Heart Study to determine the effect of socioeconomic status and psychosocial factors on CHD risk in African Americans in Mississippi.


Condition
Cardiovascular Diseases
Coronary Disease

MedlinePlus related topics: Coronary Artery Disease Heart Diseases
U.S. FDA Resources
Study Type: Observational
Study Design: Psychosocial, Cross-Sectional, Defined Population, Prospective Study
Official Title: Disparities in CHD in the Jackson Heart Study

Further study details as provided by National Heart, Lung, and Blood Institute (NHLBI):

Estimated Enrollment: 5302
Study Start Date: September 2000
Estimated Study Completion Date: March 2004
Detailed Description:

CHD is a disease that is characterized by narrowing of the coronary arteries that supply blood to the heart. As a result, insufficient amounts of oxygen and nutrients reach the heart, which can cause chest pain or heart attack. Studies have shown that people’s socioeconomic status is associated with their health, and that African Americans experience the highest rates of heart disease in the U.S. The Jackson Heart Study (JHS) is currently being conducted in Jackson, Mississippi, and is studying the factors that influence the development of cardiovascular disease in African American men and women. This study will examine data from the JHS to determine the effect of socioeconomic status and psychosocial factors on CHD risk in African Americans in Mississippi.

This study will recruit participants from the JHS only. Participants will report to the study site at least once for 4.5 hours for baseline measurements. Visits will include measurements of body size and blood pressure, an electrocardiogram, an echocardiogram, an ultrasound of the carotid artery, blood and urine collection, a lung function test, and interviews regarding health status and sociocultural aspects of life. Follow-up evaluations will occur 5 and 10 years after starting the study. Outcomes will include self-report and electrocardiogram-defined CHD, as well as measures of various social and psychological factors.

  Eligibility

Ages Eligible for Study:   35 Years to 84 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Participant in the Jackson Heart Study
  • Diagnosis of coronary heart disease

Exclusion Criteria:

  • N/A
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00415415

Locations
United States, Mississippi
Jackson Heart Study
Jackson, Mississippi, United States, 39213
Sponsors and Collaborators
Investigators
Principal Investigator: Herman Taylor, MD Professor of Medicine - University of Mississippi Medical Center
  More Information

Click here for the Jackson Heart Study website  This link exits the ClinicalTrials.gov site

Study ID Numbers: 1346, 1 K01 HL084682-01
Study First Received: December 20, 2006
Last Updated: December 20, 2006
ClinicalTrials.gov Identifier: NCT00415415  
Health Authority: United States: Federal Government

Keywords provided by National Heart, Lung, and Blood Institute (NHLBI):
Racial Disparities
Psychosocial Risk Factors
Neighborhood Socioeconomic Status
CVD
CHD

Study placed in the following topic categories:
Arterial Occlusive Diseases
Coronary Disease
Heart Diseases
Myocardial Ischemia
Vascular Diseases
Arteriosclerosis
Ischemia
Coronary Artery Disease

Additional relevant MeSH terms:
Cardiovascular Diseases

ClinicalTrials.gov processed this record on January 16, 2009