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Sponsors and Collaborators: |
Sheba Medical Center University of Haifa Israel Science Foundation |
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Information provided by: | Sheba Medical Center |
ClinicalTrials.gov Identifier: | NCT00790634 |
The purpose of this study is to characterize and compare irregularities in dopaminergic function in fronto-subcortical circuits, between Parkinson's Disease patients (ON and OFF medication) and patients with obsessive-compulsive disorder, by examining performance on cognitive tasks involving cognitive flexibility, decision-making, and attentional bias.
Condition |
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Parkinson's Disease Obsessive-Compulsive Disorder |
Study Type: | Observational |
Study Design: | Case Control, Prospective |
Official Title: | Characterizing Mechanisms of Fronto-Subcortical Dysfunction: A Comparison Between Parkinson's Disease and Obsessive-Compulsive Disorder |
Estimated Enrollment: | 100 |
Study Start Date: | December 2008 |
Estimated Study Completion Date: | December 2011 |
Estimated Primary Completion Date: | December 2011 (Final data collection date for primary outcome measure) |
Groups/Cohorts |
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Parkinson's Disease
Patients with idiopathic Parkinson's disease
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Obsessive-compulsive disorder
Individuals with a diagnosis of obsessive-compulsive disorder
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OCD controls
Healthy controls, matched in age and number to obsessive-compulsive group
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PD controls
Healthy controls, matched in age and number to Parkinson's disease group
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Ages Eligible for Study: | 16 Years to 85 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Sampling Method: | Non-Probability Sample |
private and hospital-based clinics, healthy volunteers
Inclusion Criteria:
Exclusion Criteria:
Contact: Sharon Hassin, MD | 97235305791 | shassin@post.tau.ac.il |
Contact: Sari Meril, M.Sc | 972 |
Responsible Party: | Sheba Medical Center ( Dr. Sharon Hassin, principal investigator ) |
Study ID Numbers: | SHEBA-08-5473-SH-CTIL |
Study First Received: | November 12, 2008 |
Last Updated: | November 12, 2008 |
ClinicalTrials.gov Identifier: | NCT00790634 |
Health Authority: | Israel: Ministry of Health |
Ganglion Cysts Anxiety Disorders Movement Disorders Mental Disorders Parkinson Disease Basal Ganglia Diseases |
Central Nervous System Diseases Parkinsonian Disorders Neurodegenerative Diseases Brain Diseases Obsessive-Compulsive Disorder |
Pathologic Processes Disease Nervous System Diseases |