Interest of a 30 Minutes' Intermittent Work Exercise Test in Patients With Chronic Obstructive Pulmonary Disease: Cardiac and Pulmonary Functions

This study has been completed.

Sponsored by:	University Hospital, Strasbourg, France
Information provided by:	University Hospital, Strasbourg, France
ClinicalTrials.gov Identifier:	NCT00295113

Purpose

The aim of the study is to observe the ventilatory and cardiac function (included the pulmonary arterial pressure) during an intermittent work exercise test with high density work load.

Condition	Intervention
Pulmonary Disease, Chronic Obstructive	Procedure: EFR

MedlinePlus related topics: COPD (Chronic Obstructive Pulmonary Disease) Exercise and Physical Fitness

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Prevention, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Efficacy Study
Official Title:	Interest of a 30 Minutes' Intermittent Work Exercise Test in Patients With Chronic Obstructive Pulmonary Disease: Cardiac and Pulmonary Functions

Further study details as provided by University Hospital, Strasbourg, France:

Primary Outcome Measures:

The pulmonary arterial pressure does not increase dramatically during the 30 minutes exercise test, but decreases significantly after the first 5 minutes of exercise.

Secondary Outcome Measures:

The cardiac output is stable after the first 5 minutes of exercise, despite the high intensity work loads every 5 minutes.

Enrollment:	10
Study Start Date:	November 2001
Estimated Study Completion Date:	June 2003

Eligibility

Ages Eligible for Study:	18 Years to 65 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

COPD patients (male and female) with moderate obstruction (FEV1/CV<60%)

Exclusion Criteria:

acute respiratory disease
any type of cardiac disease

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00295113

Locations

France
Hôpitaux Universitaires de Strasbourg - Service des Explorations Fonctionnelles
STRASBOURG, France, 67091

Sponsors and Collaborators

University Hospital, Strasbourg, France

Investigators

Principal Investigator:	Ruddy RICHARD, MD	Hôpitaux Universitaires de Strasbourg - Service des Explorations Fonctionnelles Respiratoires et de l'Exercice
Principal Investigator:	Evelyne LONSDORFER-WOLF, MD	Hôpitaux Universitaires de Strasbourg - Service des Explorations Fonctionnelles Respiratoires et de l'Exercice

More Information

Study ID Numbers:	2398
Study First Received:	September 13, 2005
Last Updated:	November 28, 2007
ClinicalTrials.gov Identifier:	NCT00295113
Health Authority:	France: Ministry of Health

Keywords provided by University Hospital, Strasbourg, France:

Pulmonary arterial pressure
COPD
Cardiac output
pulmonary and cardiac functions
pulmonary arterial pressure measurements

Study placed in the following topic categories:

Lung Diseases, Obstructive
Respiratory Tract Diseases
Lung Diseases

Respiration Disorders
Chronic Disease
Pulmonary Disease, Chronic Obstructive

Additional relevant MeSH terms:

Disease Attributes
Pathologic Processes

ClinicalTrials.gov processed this record on January 16, 2009