Inclusion Criteria:

• Subjects must be able to communicate and give voluntary informed consent
• Subjects must be of the male gender
• Between the ages of 18 to 65 years.
• A diagnosis of Schizophrenia or Schizoaffective disorder as determined by DSM-IV criteria.
• Not conservatorized
• A negative symptom score on the PANSS of >= 20 and an MMSE score of >24
• No clinical evidence of a current unstable medical illness
• No current clinical evidence or past history of cerebral neurological impairment (including strokes, tumors or trauma leading to loss of consciousness)
• No history of drug or alcohol dependence in the past 2 years
• No evidence of drug or alcohol abuse in the past year, as determined by the DSM-IV criteria.
• No diagnosis of Narcolepsy as determined by DSM-IV criteria
• Must have an approved contact person for the duration of the study
• May be on a stable dose of SSRI for depressive symptoms
• No history of aggression

• No uncontrolled hypertension, as defined below (subjects cannot have any of the following):

  1. a new diagnosis of hypertension, or
  2. a change in antihypertensive medications in the past 30 days, or
  3. acute hypertension (systolic>160mmHg, diastolic>100mmHg)
• Maybe on a stable dose of a benzodiazepine
• The following medications will not be allowed during the study- methylphenidate, amphetamines, pemoline, zolpidem, MAO inhibitors, anticoagulant, TCA's, or barbiturates.
• Be on a stable does of an atypical neuroleptic
• May be on a stable does of an anticonvulsant for mood stabilization

Exclusion Criteria:

• Subjects cannot be female.