Kidney Cancer in Caucasians and African Americans in the United States

This study is currently recruiting participants.

Verified by National Cancer Institute (NCI), October 2007

First Received: October 17, 2007 Last Updated: February 6, 2009 History of Changes

Sponsored by:	National Cancer Institute (NCI)
Information provided by:	National Cancer Institute (NCI)
ClinicalTrials.gov Identifier:	NCT00546338

Purpose

RATIONALE: Gathering information about how often kidney cancer occurs in Caucasians and African Americans may help the study of kidney cancer in the future.

PURPOSE: This clinical trial is studying kidney cancer in Caucasians and African Americans in the United States.

Condition	Intervention
Kidney Cancer	Genetic: cytogenetic analysis Genetic: mutation analysis Other: cytology specimen collection procedure Other: laboratory biomarker analysis Other: medical chart review Other: survey administration Procedure: evaluation of cancer risk factors Procedure: mutation carrier screening Procedure: study of high risk factors Procedure: study of socioeconomic and demographic variables

MedlinePlus related topics: Cancer Kidney Cancer

U.S. FDA Resources

Study Type:	Observational
Official Title:	Case-Control Study of Renal Cell Cancer Among Caucasians and African Americans in the United States

Further study details as provided by National Cancer Institute (NCI):

Primary Outcome Measures:

Incidence rate of renal cell cancer

Estimated Enrollment:	4900
Study Start Date:	November 2001

Detailed Description:

OBJECTIVES:

Conduct a population-based, case-control study of renal cell cancer in two areas of the Unites States with a high proportion of African American residents.

OUTLINE: This is a multicenter study.

Patients and random participants undergo in-person interviews, blood collection, and buccal cell sample collection for assays of tumor mutations and genetic analysis . Medical records, pathology reports, and stored tissue samples may also be examined.

PROJECTED ACCRUAL: A total of 2,100 cases and 2,800 controls will be accrued for this study.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

DISEASE CHARACTERISTICS:

Meets 1 of the following criteria:
- Diagnosis of kidney cancer (cases)
- Random participants (controls) chosen from the following:
  - Telephone number listing
  - Driver's license records
  - Medicare lists
Must be African American or Caucasian
Must reside in Detroit, Michigan or Chicago, Illinois

PATIENT CHARACTERISTICS:

Not specified

PRIOR CONCURRENT THERAPY:

Not specified

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00546338

Locations

United States, Maryland
Warren Grant Magnuson Clinical Center - NCI Clinical Trials Referral Office	Recruiting
Bethesda, Maryland, United States, 20892-1182
Contact: Clinical Trials Office - Warren Grant Magnusen Clinical Center 888-NCI-1937

Sponsors and Collaborators

National Cancer Institute (NCI)

Investigators

Principal Investigator:

Wong-Ho Chow, MD

NCI - Occupational and Environmental Epidemiology Branch

More Information

Additional Information:

Clinical trial summary from the National Cancer Institute's PDQ® database This link exits the ClinicalTrials.gov site

No publications provided

Study ID Numbers:	CDR0000565811, NCI-02-C-N051
Study First Received:	October 17, 2007
Last Updated:	February 6, 2009
ClinicalTrials.gov Identifier:	NCT00546338 History of Changes
Health Authority:	Unspecified

Keywords provided by National Cancer Institute (NCI):

renal cell carcinoma
renal cell carcinoma

Study placed in the following topic categories:

Urinary Tract Neoplasm
Kidney Cancer
Renal Cancer
Urologic Diseases
Kidney Neoplasms
Carcinoma, Renal Cell

Urogenital Neoplasms
Kidney Diseases
Urologic Neoplasms
Adenocarcinoma
Neoplasms, Glandular and Epithelial
Carcinoma

Additional relevant MeSH terms:

Neoplasms
Neoplasms by Site
Neoplasms by Histologic Type
Urologic Diseases
Kidney Neoplasms
Carcinoma, Renal Cell

Urogenital Neoplasms
Kidney Diseases
Urologic Neoplasms
Adenocarcinoma
Neoplasms, Glandular and Epithelial
Carcinoma

ClinicalTrials.gov processed this record on May 07, 2009