Abdominal Aortic Aneurysms and Pseudoexfoliation Syndrome

This study has been terminated.

( all patients required included )

First Received: October 17, 2007 No Changes Posted

Sponsored by:	European Georges Pompidou Hospital
Information provided by:	European Georges Pompidou Hospital
ClinicalTrials.gov Identifier:	NCT00546013

Purpose

Conflicting results have been reported concerning the association of pseudoexfoliation syndrome (PXF) and abdominal aortic aneurysms (AAA). Schumacher et al. reported an association between AAA and PXF, with no consideration of grade. However, a later study did not confirm the association between AAA and PXF. The present study aimed at comparing the relative prevalence of PXF in patients suffering from AAA and in age-matched hypertensive patients.

Condition
Abdominal Aortic Aneurysms Pseudoexfoliation Syndrome Hypertension

Genetics Home Reference related topics: early-onset glaucoma

MedlinePlus related topics: Aneurysms Aortic Aneurysm High Blood Pressure

U.S. FDA Resources

Study Type:	Observational
Study Design:	Cohort, Prospective
Official Title:	Abdominal Aortic Aneurysms Are Associated With Pseudoexfoliation Syndrome

Further study details as provided by European Georges Pompidou Hospital:

Primary Outcome Measures:

standard ophthalmologic examination to group patients according to their pseudoexfoliation status [ Time Frame: Day of standard ophthalmologic examination ]

Biospecimen Retention: None Retained

Biospecimen Description:

Enrollment:	208
Study Start Date:	December 2001
Study Completion Date:	July 2002

Groups/Cohorts
AAA group, control group AAA group : with AAA Control group: without AAA

Eligibility

Ages Eligible for Study:	60 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Non-Probability Sample

Study Population

in patients suffering from abdominal aortic aneurism as part of a routine clinical yearly follow-up and hypertensive patients without abdominal aortic aneurism and that were more than 60 years old to have similar mean ages in both groups, as pseudoexfoliation and abdominal aortic aneurism are age-related disorders

Criteria

Inclusion Criteria:

Presence of abdominal aortic aneurism
Systemic hypertension without abdominal aortic aneurism over 60 years old

Exclusion Criteria:

Unknown status for abdominal aortic aneurism

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00546013

Locations

France
Hôpital Européen Georges Pompidou
Paris, France, 75015

Sponsors and Collaborators

European Georges Pompidou Hospital

Investigators

Study Director:

Patrick Rossignol, MD, PhD

Unaffiliated

More Information

No publications provided

Study ID Numbers:	01
Study First Received:	October 17, 2007
Last Updated:	October 17, 2007
ClinicalTrials.gov Identifier:	NCT00546013 History of Changes
Health Authority:	France: Institutional Ethical Committee

Keywords provided by European Georges Pompidou Hospital:

abdominal aortic aneurysms
pseudoexfoliation syndrome
glaucoma

Study placed in the following topic categories:

Aortic Diseases
Aneurysm
Aortic Aneurysm, Abdominal
Glaucoma
Eye Diseases

Vascular Diseases
Exfoliation Syndrome
Aortic Aneurysm
Abdominal Aortic Aneurysm
Hypertension

Additional relevant MeSH terms:

Uveal Diseases
Disease
Aneurysm
Eye Diseases
Vascular Diseases
Exfoliation Syndrome
Aortic Diseases

Pathologic Processes
Iris Diseases
Aortic Aneurysm, Abdominal
Syndrome
Cardiovascular Diseases
Aortic Aneurysm
Hypertension

ClinicalTrials.gov processed this record on May 07, 2009