Self System Therapy and Chronic Low Back Pain Trial - Full Text View

Sponsored by:	Duke University
Information provided by:	Duke University
ClinicalTrials.gov Identifier:	NCT00672880

Purpose

This study is for people with chronic low back pain who may also be feeling discouraged, frustrated, or depressed. This study is testing a new therapy that is designed to specifically help these patients foster a better self-image. We hope this therapy will help them feel less discouraged and depressed and, possibly, even help reduce their stress enough that they may feel less pain.

Condition	Intervention	Phase
Low Back Pain Depression	Behavioral: Self-System Therapy Behavioral: Education Other: Standard Care	Phase IV

MedlinePlus related topics: Back Pain Depression

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Randomized, Open Label, Parallel Assignment, Efficacy Study
Official Title:	The Use of Self-System Therapy to Alter Self-Discrepancies in Chronic Low Back Pain Patients

Further study details as provided by Duke University:

Primary Outcome Measures:

Depression levels [ Time Frame: Post and 6 mo and 12 mo follow-up evaluations ] [ Designated as safety issue: No ]

Enrollment:	137
Study Start Date:	October 2003
Estimated Study Completion Date:	April 2008
Primary Completion Date:	April 2008 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
1: Experimental Psychotherapy	Behavioral: Self-System Therapy 12 sessions of structured Self-System Therapy
2: Active Comparator Spine Education	Behavioral: Education 12 sessions of spine and muscle education including life style changes and medical treatments.
3: Placebo Comparator Standard Care	Other: Standard Care Study participants continue with their usual medical care, no changes.

Detailed Description:

Patients with chronic low back pain cope with numerous life challenges, including the ability to work and decrements in physical and emotional well being. These changes impact the patients' abilities to pursue and achieve not only important personal and professional goals, but also make it difficult to maintain one's general standards of quality of daily life with personal tasks.

This study aims to address the feelings and attitudes associated with these shortfalls which frequently result in depression.

Eligible participants have been undergoing treatment for low back pain and have been identified as depressed. Study participants are randomized into one of three arms: Self System Therapy-Patients receive 12 sessions (90 Min) one-on-one with a specialized treatment regimen designed to help patients foster a better self-image and re-evaluate their life's goals in light of their new physical limitations. Modifications in goal unavailability, goal activation, and goal accomplishments are key components in this therapy delivered by a therapist. Low Back Pain Education-Patients receive 12 sessions (90 min) of detailed information about chronic low back pain, its causes and varied treatments, delivered by a research nurse. Standard Care-Patients receive their routine medical care and serve as a treatment control group. They receive the same follow up evaluations as the other two groups. Measures- Before each of the 4 evaluations, 30 day diaries are completed which measure daily pain coping, daily life events, daily mood and unpleasantness, and daily goal setting and accomplishments. Patients are evaluated at 4 times, before treatment, after treatment, and at a 6 month and 12 month intervals. An interview version of the Selves Questionnaire is used to measure self-discrepancies. Pain behaviors are assessed by means of structured observation involving videotaping. Other outcome measures include questionnaires for depression, psychosocial disability, physical disability, and cognitive, affective, motivational, and physiological areas of depressive symptomology.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Male and females 18 years and older
Low back pain for minimum of 6 months
DSM-IV diagnosis of major depressive disorder or dysthymia as determined by SCID interview, or meeting 18 or higher on Beck Depression Inventory.

Exclusion Criteria:

Diagnosis of schizophrenia, bipolar, organic brain syndrome, substance abuse within past 5 years
Hallucinations, delusions, or paranoid ideation
Concurrent medical disorders that may cause depression or significantly affect function (epilepsy, endocrine disease, COPD, diabetes), or intellectual impairment based on clinical interview
Inability to speak English; AND
Patients with pending litigation or in the process of seeking disability benefits.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00672880

Locations

United States, North Carolina
Duke University Medical Center
Durham, North Carolina, United States, 27705

Sponsors and Collaborators

Duke University

Investigators

Principal Investigator:

Francis Keefe, Ph.D

Duke University

More Information

No publications provided

Responsible Party:	Duke Universisty, Department of Psychaitry ( Frank Keefe, Ph.d. )
Study ID Numbers:	Pro00006455, NINDS Grant: RO 1NSO46422
Study First Received:	May 4, 2008
Last Updated:	April 23, 2009
ClinicalTrials.gov Identifier:	NCT00672880 History of Changes
Health Authority:	United States: Institutional Review Board

Keywords provided by Duke University:

Chronic low back pain accompanied by depression

Study placed in the following topic categories:

Signs and Symptoms
Depression
Mental Disorders
Mood Disorders
Neurologic Manifestations

Low Back Pain
Pain
Depressive Disorder
Back Pain
Behavioral Symptoms

Additional relevant MeSH terms:

Signs and Symptoms
Depression
Mental Disorders
Nervous System Diseases
Mood Disorders
Neurologic Manifestations

Low Back Pain
Pain
Depressive Disorder
Back Pain
Behavioral Symptoms

ClinicalTrials.gov processed this record on May 07, 2009