'Gateway' Gene Allows Brain Stem Cells to Grow into TumorsFriday, Apr 6, 2007
According to a new study, a gene that supports normal brain development also supports the growth of a brain tumor called glioblastoma.
Aggressive Brain Cancer Is Tied to Stem Cells ‘Gone Bad’Monday, Jan 29, 2007
The existence of rogue stem cells that refuse to die explains why an aggressive brain tumor known as glioblastoma typically
isn’t extinguished by radiation therapy. A study in the December 7, 2006 issue of Nature* shows that the therapy fails to
kill a small but potent fraction of cancerous cells – about 5 percent of those in the tumor.
Genetic Analysis of Glioblastoma Brain Tumors Can Aid in Treatment Decisions, Study ShowsWednesday, Nov 9, 2005
Screening glioblastoma brain tumors for two gene variations can reliably predict which tumors will respond to a specific class
of drugs, a new study shows. The findings may lead to improved treatment for this devastating disease.
Genetic Analysis of Childhood Brain Tumors Improves Diagnosis And Predicts SurvivalFriday, Mar 8, 2002
Doctors who treat brain tumors and other kinds of cancer have long struggled to understand why some patients respond well
to therapy while others do not. In recent years, it has become clear that the answer lies at least partially in the genes.
Two studies now show that identifying the "genetic fingerprints" of some childhood brain tumors can greatly improve diagnosis
and predict patients' long-term survival. The findings help researchers understand how the tumors develop and may lead to
improved ways of treating them.
Fact Sheet Targeted Protein Toxin Effective Against Persistent Brain TumorsMonday, Nov 24, 1997
Scientists at the National Institutes of Health have developed a new drug that can reduce the size of some persistent brain
tumors without causing severe side effects. A report of the first clinical trial of this drug, called transferrin-CRM107,
will appear in the December 1997 issue of Nature Medicine.
Tumor-Tracking Missiles: Researchers Develop a Possible New Treatment Strategy for Deadly Brain TumorsTuesday, Dec 31, 2002
In spite of advances in neurosurgery and radiation techniques, the prognosis for patients with intracranial glioma remains
devastating. Now, researchers have identified a possible new treatment strategy for this common type of malignant brain tumor.
Fact Sheet