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| Sponsored by: |
University of Sao Paulo |
|---|---|
| Information provided by: | University of Sao Paulo |
| ClinicalTrials.gov Identifier: | NCT00665795 |
Purpose
The purpose of this protocol is to study orbital structures in Graves´ Disease using multidetector computed tomography and color doppler imaging.
Some changes in orbital structures detected by imaging exams could predict severity of the ocular Graves´disease. Thus the study could be useful in improve medical management of patients with Graves´ Disease.
| Condition |
|---|
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Dysthyroid Orbitopathy |
| Study Type: | Observational |
| Study Design: | Cohort, Prospective |
| Official Title: | Morphometric Analysis of Orbital Structures in Graves´ Orbitopathy Using Multidetector Computed Tomography Scan and Color Doppler Imaging. |
| Estimated Enrollment: | 80 |
| Study Start Date: | July 2005 |
| Estimated Study Completion Date: | December 2008 |
| Groups/Cohorts |
|---|
|
1
Patients with Graves´orbitophathy.
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2
Patients with Graves´orbitophaty and detected dysthyroid optic neuropathy (DON)
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Morphometric analysis of orbital structures in Graves´ Orbitopathy using multidetector computed tomography scan and color doppler imaging:
Patients with Graves´ orbitopathy are evaluated by a complete ophthalmic examination.A prospective study with Multidetector CT scan and Color Doppler of these patients are made to develop parameters capable to predict Dysthyroid Optic Neuropathy (DON).
Eligibility| Ages Eligible for Study: | 20 Years and older |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Patients with Graves´ orbitopathy
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Allan C Goncalves, MD | 55-11-9656-4492 ext - | allanpieroni@uol.com.br |
| Contact: Mario L Monteiro, MD, PhD | 55-11-3069-7871 | mlrmonteiro@terra.com.br |
| Brazil | |
| General Hospital - University of Sao Paulo - School of Medicine | Recruiting |
| São Paulo, Brazil, 05409 000 | |
| Principal Investigator: Allan C Goncalves, MD | |
| Study Chair: | Mario L Monteiro, MD, PhD | University of Sao Paulo - School of Medicine |
More Information
| Responsible Party: | University of Sao Paulo - School of Medicine ( Allan Christian Pieroni Goncalves ) |
| Study ID Numbers: | 1152/05 |
| Study First Received: | April 22, 2008 |
| Last Updated: | June 5, 2008 |
| ClinicalTrials.gov Identifier: | NCT00665795 History of Changes |
| Health Authority: | Brazil: National Committee of Ethics in Research |
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Dysthyroid Optic Neuropathy; multidetector computed tomography; color doppler |
Grave´s Orbitopathy; Grave´s Disease morphometric analysis |
|
Goiter Autoimmune Diseases Graves Ophthalmopathy Eye Diseases Graves Disease Endocrine System Diseases Optic Nerve Disorder |
Graves' Disease Eye Diseases, Hereditary Optic Nerve Diseases Endocrinopathy Orbital Diseases Thyroid Diseases Hyperthyroidism |
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Goiter Autoimmune Diseases Immune System Diseases Graves Ophthalmopathy Eye Diseases Graves Disease |
Endocrine System Diseases Eye Diseases, Hereditary Orbital Diseases Hyperthyroidism Thyroid Diseases Exophthalmos |
