Reduction in Cardiovascular Risk Factors and Visceral Adipose Tissue in Men: Separate Effects of Diet- and Exercise-Induced Weight Loss

This study has been completed.

First Received: April 21, 2008 Last Updated: April 22, 2008 History of Changes

Sponsors and Collaborators:	Queen's University Canadian Institutes of Health Research (CIHR)
Information provided by:	Queen's University
ClinicalTrials.gov Identifier:	NCT00664547

Purpose

The purpose of the trial was to examine the independent effects of equivalent diet- or exercise-induced weight loss on obesity and related cardiovascular health risk factors. We hypothesized that exercise would result in greater reductions in obesity and health risk factors that equivalent diet (caloric restriction).

Condition	Intervention
Obesity	Behavioral: Diet Weight Loss Behavioral: Exercise Weight Loss Behavioral: Exercise Without Weight Loss

MedlinePlus related topics: Diets Exercise and Physical Fitness Obesity Weight Control

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Parallel Assignment
Official Title:	Reduction in Cardiovascular Risk Factors and Visceral Adipose Tissue in Men: Separate Effects of Diet- and Exercise-Induced Weight Loss

Further study details as provided by Queen's University:

Primary Outcome Measures:

Abdominal obesity [ Time Frame: 3 months ] [ Designated as safety issue: No ]
Insulin Resistance [ Time Frame: 3 months ] [ Designated as safety issue: No ]

Study Start Date:	September 1997
Study Completion Date:	December 1999
Primary Completion Date:	December 1999 (Final data collection date for primary outcome measure)

Arms	Assigned Interventions
C: No Intervention
DWL: Active Comparator Diet Weight Loss	Behavioral: Diet Weight Loss
EWL: Active Comparator Exercise Weight Loss	Behavioral: Exercise Weight Loss
EWS: Active Comparator Exercise without weight loss	Behavioral: Exercise Without Weight Loss

Eligibility

Ages Eligible for Study:	20 Years to 60 Years
Genders Eligible for Study:	Male
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Men between 20 and 60 yrs

Exclusion Criteria:

Smokers and diabetics

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00664547

Locations

Canada, Ontario
Queen's University
Kingston, Ontario, Canada, K7L 3N6

Sponsors and Collaborators

Queen's University

Canadian Institutes of Health Research (CIHR)

Investigators

Principal Investigator:

Robert Ross, PhD

Queen's University

More Information

Publications:

Ross R, Dagnone D, Jones PJ, Smith H, Paddags A, Hudson R, Janssen I. Reduction in obesity and related comorbid conditions after diet-induced weight loss or exercise-induced weight loss in men. A randomized, controlled trial. Ann Intern Med. 2000 Jul 18;133(2):92-103.

Responsible Party:	( Queen's University )
Study ID Numbers:	Ross 1997
Study First Received:	April 21, 2008
Last Updated:	April 22, 2008
ClinicalTrials.gov Identifier:	NCT00664547 History of Changes
Health Authority:	Canada: Canadian Institutes of Health Research

Keywords provided by Queen's University:

obesity, exercise, diet, insulin resistance

Study placed in the following topic categories:

Body Weight
Signs and Symptoms
Obesity
Weight Loss
Body Weight Changes

Nutrition Disorders
Overweight
Overnutrition
Insulin Resistance
Insulin

Additional relevant MeSH terms:

Body Weight
Signs and Symptoms
Obesity
Weight Loss

Body Weight Changes
Nutrition Disorders
Overweight
Overnutrition

ClinicalTrials.gov processed this record on May 07, 2009