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Sponsored by: |
Department of Veterans Affairs |
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Information provided by: | Department of Veterans Affairs |
ClinicalTrials.gov Identifier: | NCT00018187 |
The purpose of this study is to test the effectiveness of a combination of the drugs bupropion and mecamylamine along with a nicotine patch as a therapy for smoking cessation.
Condition | Intervention | Phase |
---|---|---|
Smoking |
Drug: Bupropion Drug: Mecamylamine Drug: Nicotine Patch |
Phase I |
Study Type: | Interventional |
Study Design: | Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Efficacy Study |
Official Title: | Combinations of Pharmacologic Smoking Cessation Treatments |
Ages Eligible for Study: | 20 Years to 40 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Subjects must be a smoker between 20 and 40 years old, have smoked at least 20 cigarettes per day for at least 2 years, wish to stop smoking and be in good general health
Study ID Numbers: | ADRD-011-98S |
Study First Received: | July 3, 2001 |
Last Updated: | January 20, 2009 |
ClinicalTrials.gov Identifier: | NCT00018187 History of Changes |
Health Authority: | United States: Food and Drug Administration |
smoking cessation bupropion mecamylamine nicotine |
Dopamine Uptake Inhibitors Nicotine polacrilex Neurotransmitter Agents Cholinergic Antagonists Nicotinic Agonists Psychotropic Drugs Mecamylamine Cardiovascular Agents Antihypertensive Agents |
Cholinergic Agents Smoking Dopamine Nicotine Bupropion Dopamine Agents Peripheral Nervous System Agents Antidepressive Agents, Second-Generation Antidepressive Agents |
Dopamine Uptake Inhibitors Neurotransmitter Uptake Inhibitors Neurotransmitter Agents Cholinergic Antagonists Molecular Mechanisms of Pharmacological Action Cholinergic Agonists Nicotinic Antagonists Nicotinic Agonists Physiological Effects of Drugs Psychotropic Drugs Mecamylamine Cholinergic Agents Habits Smoking |
Nicotine Therapeutic Uses Ganglionic Stimulants Antidepressive Agents, Second-Generation Antidepressive Agents Ganglionic Blockers Cardiovascular Agents Antihypertensive Agents Pharmacologic Actions Autonomic Agents Bupropion Dopamine Agents Peripheral Nervous System Agents Central Nervous System Agents |