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| Sponsored by: |
University of Leipzig |
|---|---|
| Information provided by: | University of Leipzig |
| ClinicalTrials.gov Identifier: | NCT00497887 |
Purpose
Atherosclerotic cardiovascular disease is the major cause of morbidity and mortality in Western societies. It is a complex genetic disorder with many genes involved and significant gene-environment interactions. The aim of the study is to identify novel genetic- and biological-markers of atherosclerosis. Atherosclerosis is assessed in the coronary arteries using coronary angiography as well as in the carotid artery (intima-media-thickness) and peripheral vessels (ankle brachial index). Association analysis of genetic and metabolic markers with atherosclerotic burden will be performed to identify novel factors of disposition to atherosclerotic vascular disease.
| Condition |
|---|
|
Atherosclerosis Coronary Arteriosclerosis Carotid Artery Diseases Genetic Predisposition to Disease Biological Markers |
| Study Type: | Observational |
| Study Design: | Cohort, Prospective |
Eligibility| Ages Eligible for Study: | 18 Years to 85 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
Patients assigned to coronary angiography
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Joachim Thiery, MD PhD | +49-341-9722201 | thiery@medizin.uni-leipzig.de |
| Contact: Gerhard Schuler, MD PhD | +49-341-8650 | schug@medizin.uni-leipzig.de |
| Germany | |
| University of Leipzig, Heart Center, Department of Cardiology | Recruiting |
| Leipzig, Germany, 04289 | |
| Contact: Gerhard Schuler, MD PhD +49-341-8650 | |
| Contact: Stephan Gielen, MD PhD +49-341-8650 | |
| Principal Investigator: Gerhard Schuler, MD PhD | |
| Sub-Investigator: Stephan Gielen, MD PhD | |
| Sub-Investigator: Frank Beutner, MD | |
| University of Leipzig, Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics | Recruiting |
| Leipzig, Germany, 04103 | |
| Contact: Joachim Thiery, MD PhD +49-341-9722201 thiery@medizin.uni-leipzig.de | |
| Contact: Daniel Teupser, MD PhD +49-341-9722204 teupser@medizin.uni-leipzig.de | |
| Principal Investigator: Joachim Thiery, MD PhD | |
| Sub-Investigator: Daniel Teupser, MD PhD | |
| Sub-Investigator: Frank Beutner, MD | |
| Sub-Investigator: Alexander Leichtle, MD PhD | |
| Sub-Investigator: Ralph Burkhardt, MD PhD | |
| Principal Investigator: | Joachim Thiery, MD PhD | University of Leipzig |
More Information
| Responsible Party: | University Leipzig ( Joachim Thiery, Daniel Teupser, Stephan Gielen, Gerhard Schuler ) |
| Study ID Numbers: | 276-2005 |
| Study First Received: | July 6, 2007 |
| Last Updated: | February 13, 2009 |
| ClinicalTrials.gov Identifier: | NCT00497887 History of Changes |
| Health Authority: | Germany: Ethics Commission |
|
Atherosclerosis Arterial Occlusive Diseases Heart Diseases Disease Susceptibility Myocardial Ischemia Vascular Diseases Central Nervous System Diseases Ischemia |
Arteriosclerosis Brain Diseases Cerebrovascular Disorders Coronary Disease Genetic Predisposition to Disease Carotid Artery Diseases Coronary Artery Disease |
|
Atherosclerosis Arterial Occlusive Diseases Disease Attributes Heart Diseases Disease Susceptibility Myocardial Ischemia Nervous System Diseases Vascular Diseases Central Nervous System Diseases |
Arteriosclerosis Brain Diseases Cerebrovascular Disorders Coronary Disease Pathologic Processes Cardiovascular Diseases Genetic Predisposition to Disease Carotid Artery Diseases Coronary Artery Disease |
