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Neuromuscular Characteristics of Individuals With Down Syndrome (DS)
This study is currently recruiting participants.
Verified by State University of New York - Upstate Medical University, March 2008
First Received: March 24, 2008   Last Updated: March 25, 2008   History of Changes
Sponsored by: State University of New York - Upstate Medical University
Information provided by: State University of New York - Upstate Medical University
ClinicalTrials.gov Identifier: NCT00643955
  Purpose

Evaluation of muscle strength and central activation of muscle in individuals with Down Syndrome


Condition Intervention
Down Syndrome
Other: muscle strength

Genetics Home Reference related topics: Down syndrome
MedlinePlus related topics: Down Syndrome
U.S. FDA Resources
Study Type: Observational
Study Design: Cohort, Cross-Sectional
Official Title: Neuromuscular Characteristics of Individuals With Down Syndrome

Further study details as provided by State University of New York - Upstate Medical University:

Primary Outcome Measures:
  • Muscle strength Central activation ratio [ Time Frame: One time ] [ Designated as safety issue: No ]

Biospecimen Retention:   None Retained

Biospecimen Description:

Estimated Enrollment: 15
Study Start Date: March 2008
Groups/Cohorts Assigned Interventions
DS
Individual with Down Syndrome
Other: muscle strength
muscle strength

  Eligibility

Ages Eligible for Study:   18 Years to 45 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

Individuals with Down Snydrome and control subjects without DS

Criteria

Inclusion Criteria:

  • 18-45 years old
  • good health with no contraindications to exercise
  • documented DS (not for control subjects)

Exclusion Criteria:

  • contraindications to exercise,
  • severe or profound MR
  • documented atherosclerotic heart disease
  • documented atlantoaxial instability
  • uncorrected congenital heart disease
  • implanted prosthetic device
  • implanted pacemaker
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00643955

Contacts
Contact: Patrick Cowley, MS 3154432114

Locations
United States, New York
IHP Recruiting
Syracuse, New York, United States, 13210
Sponsors and Collaborators
State University of New York - Upstate Medical University
  More Information

No publications provided

Responsible Party: Syracuse University ( Lori Ploutz-Snyder )
Study ID Numbers: 5495
Study First Received: March 24, 2008
Last Updated: March 25, 2008
ClinicalTrials.gov Identifier: NCT00643955     History of Changes
Health Authority: United States: Institutional Review Board

Keywords provided by State University of New York - Upstate Medical University:
Evaluation of muscle strength and central activation

Study placed in the following topic categories:
Mental Retardation
Genetic Diseases, Inborn
Chromosome Disorders
Abnormalities, Multiple
Neurologic Manifestations
Down Syndrome
Congenital Abnormalities
Neurobehavioral Manifestations

Additional relevant MeSH terms:
Mental Retardation
Pathologic Processes
Disease
Genetic Diseases, Inborn
Syndrome
Nervous System Diseases
Chromosome Disorders
Abnormalities, Multiple
Neurologic Manifestations
Down Syndrome
Congenital Abnormalities
Neurobehavioral Manifestations

ClinicalTrials.gov processed this record on May 07, 2009