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Sponsored by: |
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
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Information provided by: | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
ClinicalTrials.gov Identifier: | NCT00374426 |
To study the effectiveness of sertraline (Zoloft) in treating depression in adults with diabetes. The study will also determine whether depressed diabetic patients who have successfully responded to sertraline (Zoloft) are more likely to have depression recur if the sertraline (Zoloft) is discontinued.
Condition | Intervention | Phase |
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Major Depression Diabetes |
Drug: sertraline |
Phase IV |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study |
Official Title: | Preventing Depression Recurrence in Diabetes |
Estimated Enrollment: | 262 |
Study Start Date: | March 1998 |
Estimated Study Completion Date: | October 2004 |
Part A: Prevention of Depression Recurrence in Diabetes
Part B. Longitudinal Study of the Interrelationship of Glycemic Control and Depression
Ages Eligible for Study: | 18 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
United States, Missouri | |
Washington University School of Medicine | |
St. Louis, Missouri, United States, 63110 |
Principal Investigator: | Patrick J Lustman, Ph.D. | Washington University School of Medicine |
Study ID Numbers: | 96-0806, DK53060 |
Study First Received: | September 8, 2006 |
Last Updated: | September 8, 2006 |
ClinicalTrials.gov Identifier: | NCT00374426 History of Changes |
Health Authority: | United States: Federal Government |
depression diabetes mellitus depression recurrence |
Neurotransmitter Agents Depression Metabolic Diseases Psychotropic Drugs Diabetes Mellitus Endocrine System Diseases Depressive Disorder, Major Depressive Disorder Serotonin Uptake Inhibitors Serotonin |
Recurrence Behavioral Symptoms Mental Disorders Mood Disorders Sertraline Endocrinopathy Glucose Metabolism Disorders Metabolic Disorder Antidepressive Agents |
Disease Attributes Neurotransmitter Uptake Inhibitors Neurotransmitter Agents Molecular Mechanisms of Pharmacological Action Physiological Effects of Drugs Psychotropic Drugs Depressive Disorder, Major Pathologic Processes Mental Disorders Therapeutic Uses Sertraline Antidepressive Agents Metabolic Diseases |
Depression Diabetes Mellitus Endocrine System Diseases Depressive Disorder Serotonin Uptake Inhibitors Recurrence Pharmacologic Actions Behavioral Symptoms Serotonin Agents Mood Disorders Glucose Metabolism Disorders Central Nervous System Agents |