Pancreatic Islet Function, Insulin Sensitivity, and Chronic Complications in Pre-Diabetes - Full Text View

Sponsored by:	National Taiwan University Hospital
Information provided by:	National Taiwan University Hospital
ClinicalTrials.gov Identifier:	NCT00172796

Purpose

We, the investigators at National Taiwan University Hospital, want to compare patients' islet cell function, insulin sensitivity and risk of chronic complications with normal subjects. Moreover, we want to examine whether they are at a higher risk of having metabolic syndrome and to answer whether we should screen the phenotypes of metabolic syndrome in impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) patients. Then, we want to examine the association between insulin sensitivity and islet functions.

Condition
Prediabetic State Obesity Metabolic Syndrome X

MedlinePlus related topics: Metabolic Syndrome Obesity

U.S. FDA Resources

Study Type:	Observational
Study Design:	Natural History, Cross-Sectional, Case Control, Prospective Study

Further study details as provided by National Taiwan University Hospital:

Study Start Date:

April 2005

Detailed Description:

We, the investigators at National Taiwan University Hospital, want to compare patients' islet cell function, insulin sensitivity and risk of chronic complications with normal subjects. Moreover, we want to examine whether they are at a higher risk of having metabolic syndrome and to answer whether we should screen the phenotypes of metabolic syndrome in impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) patients. Then, we want to examine the association between insulin sensitivity and islet functions.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both

Criteria

Inclusion Criteria:

Fasting glucose 100-125 mg/dl OR oral glucose tolerance test (OGTT) 2 hour glucose 140-199 mg/dl
Diabetes mellitus

Exclusion Criteria:

Pregnancy
Children < 18 years old

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00172796

Locations

Taiwan
Department of Internal Medicine, Yun-Lin Branch, National Taiwan University Hospital	Recruiting
Yun-Lin, Taiwan, 640
Contact: Hung-Yuan Li, MD 886-5-5323911

Sponsors and Collaborators

National Taiwan University Hospital

Investigators

Principal Investigator:

Hung-Yuan Li, MD

Yun-Lin Branch, National Taiwan University Hospital

More Information

No publications provided

Study ID Numbers:	940202
Study First Received:	September 12, 2005
Last Updated:	March 29, 2006
ClinicalTrials.gov Identifier:	NCT00172796 History of Changes
Health Authority:	Taiwan: Department of Health

Keywords provided by National Taiwan University Hospital:

Metabolic syndrome

Study placed in the following topic categories:

Obesity
Metabolic Syndrome X
Metabolic Diseases
Glucose Intolerance
Diabetes Mellitus
Prediabetic State
Endocrine System Diseases
Overweight
Insulin
Abdominal Obesity Metabolic Syndrome

Body Weight
Hyperinsulinism
Signs and Symptoms
Nutrition Disorders
Overnutrition
Endocrinopathy
Insulin Resistance
Glucose Metabolism Disorders
Metabolic Disorder

Additional relevant MeSH terms:

Obesity
Metabolic Diseases
Metabolic Syndrome X
Disease
Prediabetic State
Diabetes Mellitus
Endocrine System Diseases
Overweight
Body Weight

Hyperinsulinism
Signs and Symptoms
Pathologic Processes
Syndrome
Nutrition Disorders
Overnutrition
Insulin Resistance
Glucose Metabolism Disorders

ClinicalTrials.gov processed this record on May 07, 2009