Myocardial Contrast Echocardiography in Congenital Heart Disease

This study is currently recruiting participants.

Verified by University Hospital Inselspital, Berne, December 2006

First Received: December 15, 2006 No Changes Posted

Sponsored by:	University Hospital Inselspital, Berne
Information provided by:	University Hospital Inselspital, Berne
ClinicalTrials.gov Identifier:	NCT00412685

Purpose

Patients with congenital heart disease in whom the right ventricle is exposed to pressure or volume overload show progressive systolic dysfunction of the right ventricle, the fact of which conveys substantial morbidity and mortality. The aim of this study is to investigate the myocardial perfusion in these patients by myocardial contrast echocardiography (MCE) in order to determine whether disturbed blood flow plays a role in the development of right ventricular systolic dysfunction.

Condition
D-Transposition of Great Arteries Tetralogy of Fallot

MedlinePlus related topics: Heart Diseases

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening, Cross-Sectional, Defined Population, Prospective Study
Official Title:	Quantification of the Myocardial Microcirculation by Contrast Echocardiography In Adult Patients With Congenital Heart Disease

Further study details as provided by University Hospital Inselspital, Berne:

Estimated Enrollment:	45
Study Start Date:	August 2006
Estimated Study Completion Date:	August 2007

Eligibility

Ages Eligible for Study:	18 Years to 80 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

D-TGA or Fallot-Tetralogy or Healthy person
written informed consent
Age >= 18 years

Exclusion Criteria:

Anaemia
Pregnancy and breast feeding
Diabetes mellitus
Contraindications to stress testing (ergometry or adenosine)
Known adverse reaction or hypersensitivity against V08DA (SonoVue) or its components or against adenosine

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00412685

Contacts

Contact: Tobias Rutz, MD

+41 6321 12 77

tobias.rutz@insel.ch

Locations

Switzerland
University Hospital Inselspital	Recruiting
Bern, Switzerland, 3010
Sub-Investigator: Tobias Rutz, MD

Sponsors and Collaborators

University Hospital Inselspital, Berne

Investigators

Principal Investigator:

Christian Seiler, Prof.

University Hospital Berne, Switzerland

More Information

No publications provided

Study ID Numbers:	70/06
Study First Received:	December 15, 2006
Last Updated:	December 15, 2006
ClinicalTrials.gov Identifier:	NCT00412685 History of Changes
Health Authority:	Switzerland: Swissmedic

Study placed in the following topic categories:

Great Vessels Transposition
Heart Diseases
Cardiovascular Abnormalities
Transposition of Great Vessels
Tetralogy of Fallot

Congenital Abnormalities
Heart Defects, Congenital
Transposition of Great Arteries
Fallot Tetralogy

Additional relevant MeSH terms:

Heart Diseases
Cardiovascular Abnormalities
Transposition of Great Vessels
Tetralogy of Fallot

Cardiovascular Diseases
Congenital Abnormalities
Heart Defects, Congenital

ClinicalTrials.gov processed this record on May 07, 2009