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Sponsored by: |
Samsung Medical Center |
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Information provided by: | Samsung Medical Center |
ClinicalTrials.gov Identifier: | NCT00515996 |
We plan to examine genetic polymorphism of catechol-O-methyltransferase in panic disorder and neurobiological changes of panic disorder patients after 12 weeks of pharmacotherapy with paroxetine. We plan to include 40 panic disorder patients and 40 normal control subjects in this study for 3 years.
Condition |
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Panic Disorder |
Study Type: | Observational |
Study Design: | Longitudinal, Case Control, Prospective Study |
Official Title: | Genetic Abnormalities and Changes of Autonomic Nervous System, Serotonin System, and Neuroendocrine System According to Pharmacotherapy in Panic Disorder |
Estimated Enrollment: | 80 |
Study Start Date: | January 2006 |
Estimated Study Completion Date: | December 2008 |
Groups/Cohorts |
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2: Case
paroxetine treatment group vs. normal control group
|
Ages Eligible for Study: | 20 Years to 60 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Korea, Republic of | |
Samsung Medical Center | Recruiting |
Seoul, Korea, Republic of, 135-710 | |
Contact: Tae Geun Kim, BA 82-2-3410-2975 tggo.kim@samsung.com | |
Principal Investigator: Bum-Hee Yu, M.D. & Ph.D. |
Principal Investigator: | Bum-Hee Yu, M.D. & Ph.D. | Samsung Medical Center, Sungkyunkwan University School of Medicine |
Study ID Numbers: | C-A6-418-2 |
Study First Received: | August 13, 2007 |
Last Updated: | August 13, 2007 |
ClinicalTrials.gov Identifier: | NCT00515996 History of Changes |
Health Authority: | South Korea: Samsung Medical Center |
panic disorder paroxetine genetic polymorphism serotonin |
Panic Disorder Anxiety Disorders Mental Disorders |
Congenital Abnormalities Paroxetine Serotonin |
Panic Disorder Pathologic Processes Disease Anxiety Disorders Mental Disorders |