Genetic Abnormalities and Biological Changes of Panic Disorder Patients After Pharmacotherapy

This study is currently recruiting participants.

Verified by Samsung Medical Center, August 2007

First Received: August 13, 2007 No Changes Posted

Sponsored by:	Samsung Medical Center
Information provided by:	Samsung Medical Center
ClinicalTrials.gov Identifier:	NCT00515996

Purpose

We plan to examine genetic polymorphism of catechol-O-methyltransferase in panic disorder and neurobiological changes of panic disorder patients after 12 weeks of pharmacotherapy with paroxetine. We plan to include 40 panic disorder patients and 40 normal control subjects in this study for 3 years.

Condition
Panic Disorder

MedlinePlus related topics: Panic Disorder

Drug Information available for: Serotonin

U.S. FDA Resources

Study Type:	Observational
Study Design:	Longitudinal, Case Control, Prospective Study
Official Title:	Genetic Abnormalities and Changes of Autonomic Nervous System, Serotonin System, and Neuroendocrine System According to Pharmacotherapy in Panic Disorder

Further study details as provided by Samsung Medical Center:

Estimated Enrollment:	80
Study Start Date:	January 2006
Estimated Study Completion Date:	December 2008

Groups/Cohorts
2: Case paroxetine treatment group vs. normal control group

Eligibility

Ages Eligible for Study:	20 Years to 60 Years
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

Panic disorder

Exclusion Criteria:

Other major medical or psychiatric illnesses

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00515996

Locations

Korea, Republic of
Samsung Medical Center	Recruiting
Seoul, Korea, Republic of, 135-710
Contact: Tae Geun Kim, BA 82-2-3410-2975 tggo.kim@samsung.com
Principal Investigator: Bum-Hee Yu, M.D. & Ph.D.

Sponsors and Collaborators

Samsung Medical Center

Investigators

Principal Investigator:

Bum-Hee Yu, M.D. & Ph.D.

Samsung Medical Center, Sungkyunkwan University School of Medicine

More Information

No publications provided

Study ID Numbers:	C-A6-418-2
Study First Received:	August 13, 2007
Last Updated:	August 13, 2007
ClinicalTrials.gov Identifier:	NCT00515996 History of Changes
Health Authority:	South Korea: Samsung Medical Center

Keywords provided by Samsung Medical Center:

panic disorder
paroxetine
genetic polymorphism
serotonin

Study placed in the following topic categories:

Panic Disorder
Anxiety Disorders
Mental Disorders

Congenital Abnormalities
Paroxetine
Serotonin

Additional relevant MeSH terms:

Panic Disorder
Pathologic Processes
Disease
Anxiety Disorders
Mental Disorders

ClinicalTrials.gov processed this record on May 07, 2009