Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsored by: |
Chinese Academy of Sciences |
---|---|
Information provided by: | Chinese Academy of Sciences |
ClinicalTrials.gov Identifier: | NCT00514748 |
Bilateral DIEP flap needs two groups of vessel pedicles. We suppose that the bilateral DIEP flap may survive on one vessel pedicle by means of interconnection of bilateral DIEA. This study is aimed to build a interconnected vessel system of bilateral DIEP flap based on one vessel pedicle and observe its survival in breast reconstruction.
Condition | Intervention |
---|---|
Mammaplasty |
Procedure: DIEP Procedure: Interconnected DIEP |
Study Type: | Interventional |
Study Design: | Treatment, Non-Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study |
Study Start Date: | January 2007 |
Estimated Study Completion Date: | December 2007 |
Arms | Assigned Interventions |
---|---|
1: Active Comparator
Patients who receive breast reconstruction with bilateral DIEP flap based on bilateral vessel pedicles
|
Procedure: DIEP
flap survival, operation time, flap complications, donor site morbidity.
|
2: Experimental
Patient who receive breast reconstruction with vessel interconnected DIEP flap based on one vessel pedicle
|
Procedure: Interconnected DIEP
flap survival, operation time, flap complications, donor site morbidity.
|
The DIEP flap have become the most common and primary choice in autogenous tissue breast reconstruction nowadays. In cases with inadequate abdominal soft-tissue volume or abdominal midline scar, the bilateral DIEP flap is needed.However, it need two groups of recipient vessels. So it is unavailable in cases short of two groups of recipient vessels after radiotherapy. This study is aimed to solve the problems by interconnecting one of the branches of DIEA each side. The MDCT will be used to predict the branches and perforators of DIEA both sides. According to the branches of DIEAs, one branch will be anastomosed with that on contralateral side with only one vessel pedicle preserved on one side. We believe that the whole flap can be completely nourished with only one vessel pedicle by means of vessel interconnection.
Ages Eligible for Study: | 18 Years to 65 Years |
Genders Eligible for Study: | Female |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Contact: Jie Luan, MD | 86-10-88703903 | doctorluan@hotmail.com |
China | |
Plastic Surgery Hospital | Recruiting |
Beijing, China, 100041 | |
Contact: Dali Mu, MD 86-10-88772075 doctormudali@hotmail.com | |
Principal Investigator: Jie Luan, MD | |
Sub-Investigator: Dali Mu, MD | |
Sub-Investigator: Lanhua Mu, MD |
Study Chair: | Jie Luan, MD | Plastic Surgery Hospital Affilicated to Chinese Academy of Medical Science |
Study ID Numbers: | 621125-2 |
Study First Received: | August 9, 2007 |
Last Updated: | August 9, 2007 |
ClinicalTrials.gov Identifier: | NCT00514748 History of Changes |
Health Authority: | China: Ministry of Health |
breast reconstruction DIEP vessel pedicle |
Anti-Inflammatory Agents Analgesics, Non-Narcotic Diclofenac hydroxyethylpyrrolidine Diclofenac |
Anti-Inflammatory Agents, Non-Steroidal Peripheral Nervous System Agents Analgesics Antirheumatic Agents |
Anti-Inflammatory Agents Sensory System Agents Analgesics, Non-Narcotic Therapeutic Uses Physiological Effects of Drugs Diclofenac hydroxyethylpyrrolidine |
Anti-Inflammatory Agents, Non-Steroidal Peripheral Nervous System Agents Analgesics Antirheumatic Agents Central Nervous System Agents Pharmacologic Actions |