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| Sponsored by: |
Florence Nightingale Hospital, Istanbul |
|---|---|
| Information provided by: | Florence Nightingale Hospital, Istanbul |
| ClinicalTrials.gov Identifier: | NCT00654472 |
Purpose
To compare mitral valve area in rheumatic mitral valve stenosis with cardiac magnetic resonance imaging and conventional transthoracic echocardiography.
| Condition |
|---|
|
Mitral Valve Stenosis |
| Study Type: | Observational |
| Study Design: | Case-Only, Prospective |
| Official Title: | Quantification of Rheumatic Mitral Stenosis With Cardiac Magnetic Resonance Imaging and Comparison With Transthoracic Echocardiography |
| Estimated Enrollment: | 30 |
| Study Start Date: | April 2008 |
| Estimated Study Completion Date: | June 2008 |
| Estimated Primary Completion Date: | June 2008 (Final data collection date for primary outcome measure) |
| Groups/Cohorts |
|---|
|
A
Mitral valve area above 1.5 cm2
|
|
B
Mitral valve area 1.5 cm2 and below 1.5 cm2
|
Clinical assessment of severity of mitral stenosis depends on both the presence of symptoms and mitral valve area . Evaluation of mitral valve area with transthoracic echocardiography maintains rapid, accurate analysis of valve disease and serves as a practical gold standard for clinical evaluation.
Cardiac magnetic resonance imaging (CMRI) is a recently used method that allows to evaluate cardiac structures and function noninvasively. Direct visualization of valve area with CMRI is also possible and it has been shown that the valve area assessed by CMRI planimetry correlates reliably with the invasive assessment. Velocity-encoded cardiac magnetic resonance imaging can be used to quantify mitral valve area. The objective of this study was to evaluate mitral valve area with CMRI and compare it with echocardiographic methods including 2D planimetry, Doppler continuation equation and Doppler pressure half-time
Eligibility| Ages Eligible for Study: | 20 Years to 65 Years |
| Genders Eligible for Study: | Both |
| Accepts Healthy Volunteers: | No |
| Sampling Method: | Non-Probability Sample |
tertiary care clinic
Inclusion Criteria:
Exclusion Criteria:
Contacts and Locations| Contact: Saide Aytekin, Professor | 00902122244950 ext 4038 | saideaytekin@gmail.com |
| Contact: Özlem Yıldırımtürk, Professor | 00902122244950 ext 4020 | ozlemyt@gmail.com |
| Turkey | |
| TC.Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology | Recruiting |
| Istanbul, Turkey, 34381 | |
| Contact: Saide Aytekin, Professor 00902122244950 ext 4038 saideaytekin@gmail.com | |
| Sub-Investigator: Özlem Yıldırımtürk, MD | |
| Principal Investigator: Saide Aytekin, Professor | |
| Sub-Investigator: Aylin Tuğcu, MD | |
| Sub-Investigator: Yelda Tayyareci, MD | |
| Sub-Investigator: Onur Levent Ulusoy, MD | |
| Sub-Investigator: Cihan Duran, MD | |
| Sub-Investigator: Mustafa Şirvancı, MD | |
| Florence Nightinngale Hospital | Recruiting |
| Istanbul, Turkey, 34381 | |
| Contact: Saide Ayetkin, Professor 00902122244950 ext 4038 saideaytekin@gmail.com | |
| Contact: Özlem Yıldırımtürk, MD 00902122244950 ext 4020 ozlemyt@gmail.com | |
| Study Director: | Saide Aytekin, Professor | T.C. Istanbul Bilim University, Florence Nightingale Hospital, Division of Cardiology |
More Information
| Responsible Party: | T.C. Istanbul Bilim University, Florence Nightingale Hospital ( Prof. Dr. Saide Aytekin ) |
| Study ID Numbers: | OY1975 |
| Study First Received: | April 2, 2008 |
| Last Updated: | April 7, 2008 |
| ClinicalTrials.gov Identifier: | NCT00654472 History of Changes |
| Health Authority: | Turkey:Ministry of Health; Turkey: Ethics Commitee |
|
magnetic resonance imaging, mitral valve area |
|
Pathological Conditions, Anatomical Heart Diseases Mitral Valve Stenosis |
Constriction, Pathologic Rheumatic Diseases Heart Valve Diseases |
|
Pathological Conditions, Anatomical Heart Diseases Mitral Valve Stenosis |
Cardiovascular Diseases Constriction, Pathologic Heart Valve Diseases |
