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Collection of Tissue & Blood From Patients w/ Benign & Malignant Tumors of the Soft Tissue & Gastrointestinal Tract
This study is currently recruiting participants.
Verified by Memorial Sloan-Kettering Cancer Center, December 2008
First Received: December 21, 2007   Last Updated: December 9, 2008   History of Changes
Sponsors and Collaborators: Memorial Sloan-Kettering Cancer Center
National Cancer Institute (NCI)
Information provided by: Memorial Sloan-Kettering Cancer Center
ClinicalTrials.gov Identifier: NCT00582647
  Purpose

Doctors at Memorial Sloan-Kettering Cancer Center and at other institutions study normal and cancer cells. To study these cells we need to have human tissue, body fluids, and blood. You will be having or have had a procedure to remove tissue. We would like to use some of this tissue. We will use it for laboratory studies on the causes, prevention, diagnosis and treatment of sarcoma, gastrointestinal or other intra-abdominal cancers. We will only use extra tissue left over after all needed testing has been done. We would also like to study components of your immune blood cells and blood serum (the liquid portion of your blood). In some patients we will take a blood sample before the tissue or body fluid is removed, usually at the same time that other routine pre-procedure blood tests are drawn. If we need more blood, it will be drawn when you are seeing your doctor anyway. We will not draw more than 50cc (4-5 tablespoons) at any one time. With your permission, we may also send a small portion of the blood to a repository at the National Cancer Institute. This sample will be used to identify special proteins in the blood that may be useful for diagnosing cancer. Information about your treatment and your response to treatment may be linked to the tissue specimens obtained. This information may be important for the research studies that will be done on your tissue and blood specimens. All of this information will be kept in strictest confidence; we will use it only for biomedical research. Your name will not be used in any report.


Condition
Esophageal Cancer
Bile Duct Neoplasms
Gastric Cancer
Liver Cancer
Melanoma
Pancreatic Cancer
Sarcoma

MedlinePlus related topics: Cancer Esophageal Cancer Esophagus Disorders Liver Cancer Melanoma Pancreatic Cancer Soft Tissue Sarcoma Stomach Cancer
U.S. FDA Resources
Study Type: Observational
Study Design: Cohort, Prospective
Official Title: Collection of Tissue, Blood and Other Specimens From Patients With Benign and Malignant Tumors of the Soft Tissue, Gastrointestinal Tract, and Other Intra-Abdominal Sites.

Further study details as provided by Memorial Sloan-Kettering Cancer Center:

Primary Outcome Measures:
  • To obtain & store tissues, blood, peritoneal, pleural, cyst & other gastrointestinal fluid from patients with benign or malignant tumors in order to carry out future laboratory studies on the causes, prevention, diagnosis & treatment of certain cancers. [ Time Frame: 2 years ] [ Designated as safety issue: No ]

Biospecimen Retention:   Samples With DNA

Biospecimen Description:

Tissue, Blood, Peritoneal, Pleural, Cyst, and Other gastrointestinal fluid


Estimated Enrollment: 3000
Study Start Date: March 2000
Estimated Study Completion Date: December 2010
Estimated Primary Completion Date: December 2010 (Final data collection date for primary outcome measure)
Detailed Description:

This is a protocol to obtain and store tissue, blood, peritoneal, pleural, cyst, and other gastrointestinal fluid from patients with benign or malignant tumors of the soft tissues, gastrointestinal tract, and other intra-abdominal sites. The tissues and other specimens will be used to carry out laboratory studies concerning the immunology and biology of the tumor.

  Eligibility

Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population

Primary Care Clinic

Criteria

Inclusion Criteria:

  • All patients with benign or malignant tumors of the soft tissues, gastrointestinal tract, and other intra-abdominal sites who will have or have had tissue, peritoneal, pleural, cyst, or other gastrointestinal fluid removed for therapeutic or diagnostic purposes.
  • Patients will be entered without preference for any particular racial/ethnic group.
  • Patients may have received prior hormonal therapy, cytotoxic chemotherapy, irradiation, immunotherapy or surgical therapy.
  • Tissue and body fluid specimens must be a large enough quantity to allow routine pathological analysis, with the research laboratory specimen removed from the residual specimen which would otherwise be discarded.

Exclusion Criteria:

  • N/A
  Contacts and Locations
Please refer to this study by its ClinicalTrials.gov identifier: NCT00582647

Contacts
Contact: Peter Allen, MD allenp@mskcc.org

Locations
United States, New York
Memorial Sloan-Kettering Cancer Center Recruiting
New York, New York, United States, 10065
Sponsors and Collaborators
Memorial Sloan-Kettering Cancer Center
Investigators
Principal Investigator: Peter Allen, MD Memorial Sloan-Kettering Cancer Center
  More Information

Additional Information:
No publications provided

Responsible Party: Memorial Sloan-Kettering Cancer Center ( Peter Allen, MD )
Study ID Numbers: 00-032
Study First Received: December 21, 2007
Last Updated: December 9, 2008
ClinicalTrials.gov Identifier: NCT00582647     History of Changes
Health Authority: United States: Food and Drug Administration

Study placed in the following topic categories:
Liver Diseases
Gastrointestinal Diseases
Pancreatic Neoplasms
Esophageal Neoplasms
Melanoma
Liver Neoplasms
Neoplasms, Connective and Soft Tissue
Soft Tissue Sarcomas
Stomach Diseases
Stomach Neoplasms
Biliary Tract Diseases
Neoplasms, Germ Cell and Embryonal
Nevus, Pigmented
Neuroepithelioma
Endocrine Gland Neoplasms
Digestive System Neoplasms
Biliary Tract Neoplasms
Endocrine System Diseases
Esophageal Cancer
Neuroendocrine Tumors
Neuroectodermal Tumors
Malignant Mesenchymal Tumor
Soft Tissue Neoplasms
Digestive System Diseases
Esophageal Disorder
Bile Duct Diseases
Head and Neck Neoplasms
Sarcoma
Pancreatic Diseases
Gastrointestinal Neoplasms

Additional relevant MeSH terms:
Liver Diseases
Gastrointestinal Diseases
Pancreatic Neoplasms
Esophageal Neoplasms
Neoplasms, Nerve Tissue
Melanoma
Liver Neoplasms
Neoplasms, Connective and Soft Tissue
Neoplasms by Site
Stomach Diseases
Stomach Neoplasms
Biliary Tract Diseases
Neoplasms, Germ Cell and Embryonal
Nevi and Melanomas
Endocrine Gland Neoplasms
Digestive System Neoplasms
Biliary Tract Neoplasms
Neoplasms by Histologic Type
Endocrine System Diseases
Neuroendocrine Tumors
Neuroectodermal Tumors
Soft Tissue Neoplasms
Neoplasms
Digestive System Diseases
Bile Duct Diseases
Head and Neck Neoplasms
Sarcoma
Pancreatic Diseases
Gastrointestinal Neoplasms
Bile Duct Neoplasms

ClinicalTrials.gov processed this record on May 07, 2009