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Sponsored by: |
National Heart, Lung, and Blood Institute (NHLBI) |
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Information provided by: | National Heart, Lung, and Blood Institute (NHLBI) |
ClinicalTrials.gov Identifier: | NCT00005323 |
To conduct an epidemiologic study of persistent pulmonary hypertension of the newborn ( PPHN) infant.
Condition |
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Lung Diseases Cardiovascular Diseases Defect, Congenital Heart Heart Diseases Persistent Fetal Circulation Syndrome |
Study Type: | Observational |
Study Design: | Natural History |
Study Start Date: | December 1991 |
Estimated Study Completion Date: | November 1996 |
BACKGROUND:
The study on the epidemiology of persistent pulmonary hypertension of the newborn (PPHN) was a subproject within a Specialized Center of Research (SCOR) in Lung Biology and Diseases in Infants and Children. The SCOR and its subproject were awarded in December, 1991. Dollars were estimated at 20 percent of total center dollars.
DESIGN NARRATIVE:
Data from a previous study of PPHN were analyzed. The objectives were to: identify the effects of a variety of potentially adverse prenatal exposures from interview data; formulate multi-variate models of risk of PPHN to determine if smoking or use of prostaglandin inhibitors increased the risk of PPHN; explore associations of PPHN with history of illicit drug use and maternal hypoxia; examine the relationships of postnatal care and perinatal risk factors on the incidence and outcome of PPHN; test the relationships of PPHN to the biochemical presence of nicotine and drugs in neonatal urine.
Genders Eligible for Study: | Male |
Accepts Healthy Volunteers: | No |
No eligibility criteria
Study ID Numbers: | 4104 |
Study First Received: | May 25, 2000 |
Last Updated: | June 23, 2005 |
ClinicalTrials.gov Identifier: | NCT00005323 History of Changes |
Health Authority: | United States: Federal Government |
Heart Diseases Respiratory Tract Diseases Cardiovascular Abnormalities Hypertension, Pulmonary Lung Diseases |
Persistent Fetal Circulation Syndrome Infant, Newborn, Diseases Congenital Abnormalities Heart Defects, Congenital Hypertension |
Heart Diseases Disease Cardiovascular Abnormalities Pathologic Processes Respiratory Tract Diseases Hypertension, Pulmonary Lung Diseases |
Syndrome Persistent Fetal Circulation Syndrome Infant, Newborn, Diseases Cardiovascular Diseases Congenital Abnormalities Heart Defects, Congenital |