Pilot Study of Vestibular Rehabilitation Training for Panic Disorder With Vestibular Dysfunction

This study has been completed.

First Received: October 18, 1999 Last Updated: June 23, 2005 History of Changes

Sponsors and Collaborators:	National Center for Research Resources (NCRR) University of Pittsburgh
Information provided by:	Office of Rare Diseases (ORD)
ClinicalTrials.gov Identifier:	NCT00004366

Purpose

OBJECTIVES:

I. Evaluate whether vestibular rehabilitation training is of value in reducing anxiety symptoms in patients with panic disorder with or without agoraphobia who have vestibular dysfunction as identified by clinical vestibular tests.

Condition	Intervention
Vestibular Diseases Agoraphobia Panic Disorder	Procedure: Physical therapy

MedlinePlus related topics: Anxiety Panic Disorder Rehabilitation

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Educational/Counseling/Training, Efficacy Study

Further study details as provided by Office of Rare Diseases (ORD):

Estimated Enrollment:	20
Study Start Date:	August 1995
Estimated Study Completion Date:	May 2000

Detailed Description:

PROTOCOL OUTLINE: During the first 4 weeks of study, patients meet with a clinical nurse specialist once a week for approximately 1 hour. During this time, the nature of the anxiety disorder is explained and exposure to previously feared situations is encouraged.

Only patients who remain symptomatic at a stable level following self-exposure will proceed with rehabilitation training.

Patients meet with a physical therapist once a week for 4 weeks to further evaluate the extent of problems associated with balance. Then, patients undergo weekly 1 hour exercises for 8 weeks with the physical therapist, focusing on sensation, head and eye coordination, movement with eyes opened and closed, and gait. Concurrently, patients meet with the clinical nurse specialist every 4 weeks during and after physical therapy to evaluate the effects of vestibular treatment on anxiety symptoms. Training is continued if patient is symptomatic; otherwise, patient is discharged from study.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Diagnosed panic disorder with or without agoraphobia
Vestibular dysfunction, as defined by abnormalities in the caloric and/or rotational tests
Continued symptomatology after general instructions of the importance of exposure to feared situations
Absence of acute symptoms of anxiety or depression assessed to need immediate clinical care

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00004366

Sponsors and Collaborators

National Center for Research Resources (NCRR)

University of Pittsburgh

Investigators

Study Chair:

Rolf G. Jacob

University of Pittsburgh

More Information

No publications provided

Study ID Numbers:	199/11944, UPITTS-11760S-950866, 11760S-950866
Study First Received:	October 18, 1999
Last Updated:	June 23, 2005
ClinicalTrials.gov Identifier:	NCT00004366 History of Changes
Health Authority:	United States: Federal Government

Keywords provided by Office of Rare Diseases (ORD):

agoraphobia
anxiety disorder
disease-related problem/condition
neurologic and psychiatric disorders

panic disorder
rare disease
vestibular diseases

Study placed in the following topic categories:

Panic Disorder
Otorhinolaryngologic Diseases
Anxiety Disorders
Mental Disorders

Rare Diseases
Agoraphobia
Vestibular Diseases
Ear Diseases

Additional relevant MeSH terms:

Panic Disorder
Otorhinolaryngologic Diseases
Pathologic Processes
Disease
Anxiety Disorders

Mental Disorders
Agoraphobia
Vestibular Diseases
Ear Diseases
Labyrinth Diseases

ClinicalTrials.gov processed this record on May 07, 2009