Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsors and Collaborators: |
National Center for Research Resources (NCRR) University of Rochester |
---|---|
Information provided by: | Office of Rare Diseases (ORD) |
ClinicalTrials.gov Identifier: | NCT00004288 |
OBJECTIVES:
I. Assess the safety and efficacy of olsalazine, a dimer of 5-aminosalicylic acid, in men with ankylosing spondylitis unresponsive to nonsteroidal anti-inflammatory drugs and physiotherapy.
Condition | Intervention | Phase |
---|---|---|
Ankylosing Spondylitis |
Drug: olsalazine |
Phase II |
Study Type: | Interventional |
Study Design: | Treatment |
Estimated Enrollment: | 4 |
Study Start Date: | May 1996 |
Estimated Study Completion Date: | December 1999 |
PROTOCOL OUTLINE: Patients are treated with daily olsalazine. The dose is increased each week until the protocol dose is reached.
Supplemental acetaminophen is allowed; nonsteroidal anti-inflammatory drugs continue unchanged. Concurrent sulfasalazine is prohibited.
Ages Eligible for Study: | 18 Years to 65 Years |
Genders Eligible for Study: | Male |
Accepts Healthy Volunteers: | No |
PROTOCOL ENTRY CRITERIA:
--Disease Characteristics--
Study ID Numbers: | 199/11716, URMC-44 |
Study First Received: | October 18, 1999 |
Last Updated: | June 23, 2005 |
ClinicalTrials.gov Identifier: | NCT00004288 History of Changes |
Health Authority: | United States: Federal Government |
ankylosing spondylitis genetic diseases and dysmorphic syndromes rare disease |
Anti-Inflammatory Agents Spinal Diseases Joint Diseases Spondylarthropathy Rare Diseases Bone Diseases Olsalazine Musculoskeletal Diseases Analgesics, Non-Narcotic Arthritis |
Spondylitis, Ankylosing Anti-Inflammatory Agents, Non-Steroidal Peripheral Nervous System Agents Analgesics Antirheumatic Agents Spondylarthritis Spondylitis Spondylarthropathies Ankylosis |
Anti-Inflammatory Agents Physiological Effects of Drugs Infection Bone Diseases Musculoskeletal Diseases Sensory System Agents Arthritis Therapeutic Uses Spondylitis, Ankylosing Anti-Inflammatory Agents, Non-Steroidal Analgesics Spondylarthritis Spondylitis |
Ankylosis Spondylarthropathies Spinal Diseases Joint Diseases Gastrointestinal Agents Pharmacologic Actions Olsalazine Bone Diseases, Infectious Analgesics, Non-Narcotic Peripheral Nervous System Agents Antirheumatic Agents Central Nervous System Agents |