Helicobacter Pylori and Acute Alcohol Induced Pancreatitis

This study has been completed.

First Received: June 20, 2007 Last Updated: June 21, 2007 History of Changes

Sponsored by:	University of Tampere
Information provided by:	University of Tampere
ClinicalTrials.gov Identifier:	NCT00490386

Purpose

This study is performed to measure wether Helicobacter Pylori has an effect on the incidence and course of acute alcohol induced pancreatitis

Condition
Pancreatitis, Acute Helicobacter Infections

U.S. FDA Resources

Study Type:	Observational
Study Design:	Natural History, Cross-Sectional, Defined Population, Retrospective Study
Official Title:	Alkoholihaimatulehduksen Uusiminen

Further study details as provided by University of Tampere:

Enrollment:	100
Study Start Date:	June 2006

Detailed Description:

A recent pilot study unexpectedly discovered, that Helicobacter pylori infection was rare in patients having their first acute alcohol induced pancreatitis (AAIP) when compared to subjects with similar alcohol use but no history of pancreatitis. This subject has not been studied in humans until now. Therefore we seek to study, with a larger material, wether AAIP is associated with lower prevalence of Helicobacter pylori, by measuring the antibodies against Helicobacter pylori from the sera of AAIP patients and from a control group of alcoholics with no history of AAIP.

Eligibility

Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Acute alcohol pancreatitis (first)

Exclusion Criteria:

Death during hospitalization

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00490386

Locations

Finland, Pirkanmaa
Tampere University Hospital
Tampere, Pirkanmaa, Finland

Sponsors and Collaborators

University of Tampere

Investigators

Principal Investigator:	Jahangir A Khan, MS	Department of Gastroenterology and Alimentary Tract Surgery, Tampere University
Study Director:	Isto Nordback, MD	1Department of Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital

More Information

Publications:

Pelli H, Herzig KH, Uotila S, Raty S, Laine S, Sand J, Nordback I. Duodenal diazepam-binding protein expression and plasma cholecystokinin after alcoholic pancreatitis. Scand J Clin Lab Invest. 2006;66(8):677-83.

Study ID Numbers:	R00126-1
Study First Received:	June 20, 2007
Last Updated:	June 21, 2007
ClinicalTrials.gov Identifier:	NCT00490386 History of Changes
Health Authority:	Finland: Ethics Committee

Keywords provided by University of Tampere:

Retrospective
Length of Stay
Helicobacter pylori

Study placed in the following topic categories:

Bacterial Infections
Digestive System Diseases
Pancreatic Diseases
Helicobacter Infections

Pancreatitis
Ethanol
Gram-Negative Bacterial Infections

Additional relevant MeSH terms:

Bacterial Infections
Digestive System Diseases
Pancreatic Diseases
Helicobacter Infections

Infection
Pancreatitis
Gram-Negative Bacterial Infections

ClinicalTrials.gov processed this record on May 07, 2009