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Sponsored by: |
University Hospital, Rouen |
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Information provided by: | University Hospital, Rouen |
ClinicalTrials.gov Identifier: | NCT00213460 |
Small bowel involvement is still recognized to be associated with great morbidity and mortality in SSc patients, leading particularly to malabsorption and intestinal pseudo-obstruction. Intestinal disorders directly related to SSc have, in fact, been reported to be one of the most common causes of death. In a previous prospective study, we have demonstrated the high prevalence of small intestinal involvement in SSc patients, using upper intestinal manometry; in turn, 88% of our SSc patients had upper intestinal motor disturbances. However, to date, no authors have yet analyzed the course of upper intestinal motor dysfunction in SSc. The aims of this study were therefore to assess the 5-year course of small bowel motor disorders, using manometry in patients with systemic sclerosis (SSc), and to investigate for an association between upper intestinal motor dysfunction outcome and other clinical manifestations of SSc.
Condition |
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Systemic Sclerosis |
Study Type: | Observational |
Study Design: | Screening, Longitudinal, Defined Population, Prospective Study |
Official Title: | Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-Year Manometric Follow-Up |
Ages Eligible for Study: | 18 Years to 80 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
patients with systemic sclerosis, who had an upper intestinal tract manometry 5 years before, with:
Exclusion Criteria:
Study ID Numbers: | 2000/103HP |
Study First Received: | September 13, 2005 |
Last Updated: | September 13, 2005 |
ClinicalTrials.gov Identifier: | NCT00213460 History of Changes |
Health Authority: | France: Afssaps - French Health Products Safety Agency |
Skin Diseases Connective Tissue Diseases Scleroderma |
Scleroderma, Diffuse Sclerosis Scleroderma, Systemic |
Pathologic Processes Skin Diseases Connective Tissue Diseases |
Scleroderma, Diffuse Sclerosis Scleroderma, Systemic |