Cerebral Resonance Magnetic Imaging During Rectal Distention

This study has been withdrawn prior to recruitment.

( patients with inflammatory colitis not included )

First Received: September 13, 2005 Last Updated: April 24, 2007 History of Changes

Sponsored by:	University Hospital, Rouen
Information provided by:	University Hospital, Rouen
ClinicalTrials.gov Identifier:	NCT00213330

Purpose

Irritable bowel syndrome is responsible for chronic abdominal pain, diarrhea and/or constipation. It is a very frequent problem. However, the exact cause of irritable bowel syndrome remains unknown. The purpose of this study is to look for a different cerebral response by magnetic resonance imaging after rectal stimulation in patients with irritable bowel syndrome compared to healthy subjects and to patients with digestive organic disease. Our hypothesis is that irritable bowel syndrome could be a problem of cerebral integration of visceral stimulation.

Condition	Intervention
Ulcerative Colitis Irritable Bowel Syndrome	Procedure: rectal distension

Genetics Home Reference related topics: Crohn disease

MedlinePlus related topics: MRI Scans Ulcerative Colitis

U.S. FDA Resources

Study Type:	Observational
Study Design:	Screening, Cross-Sectional, Defined Population, Prospective Study
Official Title:	Cerebral Activity During Rectal Pain in Patients With Irritable Bowel Syndrome or Inflammatory Bowel Disease:Resonance Magnetic Imaging Study.

Further study details as provided by University Hospital, Rouen:

Estimated Enrollment:	30
Study Start Date:	April 2003
Estimated Study Completion Date:	February 2006

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	Yes

Criteria

Inclusion Criteria:

healthy subjects irritable bowel syndrome (Rome II criteria) colitis ulcerative

Exclusion Criteria:

pregnant or breast feeding metallic material implanted good tolerance of rectal distension acute phase of ulcerative colitis

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00213330

Locations

France
University hospital of Rouen
Rouen, France, 76031

Sponsors and Collaborators

University Hospital, Rouen

Investigators

Principal Investigator:

Emmanuel Gérardin, MD

University Hospital, Rouen

More Information

No publications provided

Study ID Numbers:	01 - 105 HP
Study First Received:	September 13, 2005
Last Updated:	April 24, 2007
ClinicalTrials.gov Identifier:	NCT00213330 History of Changes
Health Authority:	France: Afssaps - French Health Products Safety Agency

Keywords provided by University Hospital, Rouen:

cerebral activity
rectal distension
colitis ulcerative
irritable bowel syndrome
magnetic resonance imaging

Study placed in the following topic categories:

Dilatation, Pathologic
Gastrointestinal Diseases
Ulcer
Colonic Diseases
Inflammatory Bowel Diseases
Colitis, Ulcerative
Pain

Intestinal Diseases
Digestive System Diseases
Irritable Bowel Syndrome
Gastroenteritis
Colitis
Colonic Diseases, Functional

Additional relevant MeSH terms:

Disease
Gastrointestinal Diseases
Ulcer
Colonic Diseases
Inflammatory Bowel Diseases
Colitis, Ulcerative
Intestinal Diseases

Pathologic Processes
Digestive System Diseases
Syndrome
Irritable Bowel Syndrome
Gastroenteritis
Colitis
Colonic Diseases, Functional

ClinicalTrials.gov processed this record on May 07, 2009