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The Prevalence of Rheumatic Heart Disease in School Children in Fiji
This study is ongoing, but not recruiting participants.
First Received: October 23, 2008   No Changes Posted
Sponsors and Collaborators: Queensland Institute of Medical Research
National Institute of Allergy and Infectious Diseases (NIAID)
Menzies School of Health Research
University of Melbourne
Information provided by: Queensland Institute of Medical Research
ClinicalTrials.gov Identifier: NCT00779662
  Purpose

This study is an epidemiological observational cross-sectional study designed to estimate the prevalence of echocardiographically confirmed RHD in school children from 5-14 years of age in Fiji. The study will be conducted in the Central Division of Fiji within a selection of up to16 primary schools located in the Korovou/Tailevu and Rewa/Nausori sub-divisions. School children will be enrolled after informed consent has been obtained. A standard cardiac examination (auscultation) will be performed as part of the routine annual health check by both school nurses, who have attended a training workshop, and by a paediatrician. All children with or without murmur will have a screening echocardiogram performed at a subsequent visit. Children found to have possible, probable or definite RHD or other cardiac pathology on the screening echocardiogram, will have a full echocardiogram performed by the echocardiography technician at the time of the second study visit. They will all also be referred to a paediatric cardiologist for further investigation and management and monitoring . Cases of RHD will be referred to and followed up by the National Fiji RHD register based at CWMH in Suva.


Condition
Rheumatic Heart Disease

MedlinePlus related topics: Heart Diseases
U.S. FDA Resources
Study Type: Observational
Study Design: Ecologic or Community, Cross-Sectional
Official Title: The Prevalence of Rheumatic Heart Disease in School Children in Fiji

Further study details as provided by Queensland Institute of Medical Research:

Biospecimen Retention:   None Retained

Biospecimen Description:

Estimated Enrollment: 2000
Study Start Date: February 2008
Estimated Study Completion Date: December 2008
Estimated Primary Completion Date: December 2008 (Final data collection date for primary outcome measure)
  Eligibility

Ages Eligible for Study:   5 Years to 14 Years
Genders Eligible for Study:   Both
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population

The study will be conducted in the Central Division of Fiji within a selection of up to16 primary schools located in the Korovou/Tailevu and Rewa/Nausori sub-divisions.

Criteria

Inclusion Criteria:

  • Informed consent will be obtained for all participants
  • All children between the ages of 5-14 Years are eligible for the study.

Exclusion Criteria:

  • None
  Contacts and Locations
No Contacts or Locations Provided
  More Information

No publications provided

Responsible Party: Menzies School of Health Research ( Samantha Colquhoun )
Study ID Numbers: 07- 0070, U01AI60579
Study First Received: October 23, 2008
Last Updated: October 23, 2008
ClinicalTrials.gov Identifier: NCT00779662     History of Changes
Health Authority: Australia: Human Research Ethics Committee

Keywords provided by Queensland Institute of Medical Research:
Rheumatic Heart Disease
Streptococcus
Fiji

Study placed in the following topic categories:
Bacterial Infections
Fever
Gram-Positive Bacterial Infections
Heart Diseases
Rheumatic Heart Disease
Musculoskeletal Diseases
Streptococcal Infections
Acute Articular Rheumatism
Connective Tissue Diseases
Rheumatic Fever
Rheumatic Diseases

Additional relevant MeSH terms:
Bacterial Infections
Gram-Positive Bacterial Infections
Rheumatic Heart Disease
Heart Diseases
Musculoskeletal Diseases
Streptococcal Infections
Connective Tissue Diseases
Cardiovascular Diseases
Rheumatic Fever
Rheumatic Diseases

ClinicalTrials.gov processed this record on May 07, 2009