Prevalence of Lymphoma in IBD

This study is ongoing, but not recruiting participants.

First Received: December 19, 2007 No Changes Posted

Sponsored by:	Indiana University
Information provided by:	Indiana University
ClinicalTrials.gov Identifier:	NCT00577538

Purpose

Patients with inflammatory bowel disease (IBD) may be at increased risk of lymphoma. The majority of lymphomas in patients with IBD occur in areas of active inflammation. The relationship between IBD and lymphoproliferative disease is however unclear, since both chronic inflammation as well as medications used to treat IBD (especially immunosuppressives - Azathioprine or 6-MP - and anti-TNF alpha agents) have been associated with increased risk of lymphoma. We plan to study the association between IBD and lymphoma in a large, mixed, community based and referral population from the IBD database at Indiana University.

Condition
Lymphoma Inflammatory Bowel Disease

Genetics Home Reference related topics: Crohn disease

MedlinePlus related topics: Lymphoma

U.S. FDA Resources

Study Type:	Observational
Study Design:	Case Control, Retrospective
Official Title:	Prevalence and Risk Factor for Lymphoproliferative Disease in Patients With Inflammatory Bowel Disease

Further study details as provided by Indiana University:

Biospecimen Retention: None Retained

Biospecimen Description:

Estimated Enrollment:	6
Study Start Date:	April 2006
Estimated Study Completion Date:	December 2007

Groups/Cohorts
1
2

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No
Sampling Method:	Probability Sample

Study Population

Patients diagnosed with both Inflammatory bowel disease and lymphoma over the last 30 years.

Criteria

Inclusion Criteria: - Inflammatory Bowel disease - Lymphoma

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00577538

Locations

United States, Indiana
Indiana University Medical Center
Indianapolis, Indiana, United States, 46202

Sponsors and Collaborators

Indiana University

Investigators

Principal Investigator:

Michael V. Chiorean, M.D.

Indiana University

More Information

No publications provided

Responsible Party:	Indiana University ( Michael Chiorean M.D. )
Study ID Numbers:	060358, IRB# 0603-58
Study First Received:	December 19, 2007
Last Updated:	December 19, 2007
ClinicalTrials.gov Identifier:	NCT00577538 History of Changes
Health Authority:	United States: Institutional Review Board

Study placed in the following topic categories:

Lymphatic Diseases
Immunoproliferative Disorders
Digestive System Diseases
Gastrointestinal Diseases
Inflammatory Bowel Diseases

Gastroenteritis
Lymphoproliferative Disorders
Intestinal Diseases
Lymphoma

Additional relevant MeSH terms:

Lymphatic Diseases
Neoplasms
Immunoproliferative Disorders
Neoplasms by Histologic Type
Digestive System Diseases
Immune System Diseases

Gastrointestinal Diseases
Inflammatory Bowel Diseases
Lymphoproliferative Disorders
Gastroenteritis
Intestinal Diseases
Lymphoma

ClinicalTrials.gov processed this record on May 07, 2009