Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsors and Collaborators: |
Singapore National Eye Centre Singapore Eye Research Institute |
---|---|
Information provided by: | Singapore National Eye Centre |
ClinicalTrials.gov Identifier: | NCT00347347 |
A thorough ophthalmic examination of a child must include a refraction and this is often done with cycloplegia. In our study, we aim to determine at which age group a non-cycloplegic refraction technique closely correlates with a cycloplegic refraction and hence, would obviate the need for cycloplegic refraction in our routine clinical practice.
Condition |
---|
Myopia Refractive Error |
Study Type: | Observational |
Study Design: | Longitudinal, Defined Population, Prospective Study |
Estimated Enrollment: | 150 |
Study Start Date: | February 2006 |
Estimated Study Completion Date: | December 2006 |
The accommodative response in young phakic patients has been known to result in over-estimation of myopia and subsequently inappropriate prescriptions.
Therefore, the rationale for cycloplegia is to inhibit the accommodative response in order to obtain a true measurement of the refractive error.
Different cycloplegic agents have been in common use for the last five decades. Cyclopentolate is widely used and is commercially available in concentrations of 0.5% and 1%. Tropicamide is another widely used cycloplegic agent and is available in 0.5% and 1% concentrations.
The advantages of a non-cycloplegic technique would be firstly, the avoidance of any possible harmful effects from the cycloplegic agents used. Secondly, it would vastly reduce waiting times for parents and children and allow for a much more efficient clinical service. Finally, there may be a significant cost-saving feature involved if these cycloplegic agents are no longer required.
This will be a prospective clinical audit/survey involving children between the ages of 4 years and 13 years who attend the paediatric ophthalmology clinics in KK Women’s and Children’s Hospital as well as the Singapore National Eye Centre.
All eligible children will have had a cycloplegic refraction and a non-cycloplegic refraction with fogging. A survey of children between the ages of 4 and 13 years who have had refraction with both these techniques will be undertaken and the difference in spherical error between the 2 techniques will be recorded for each child. We aim to accumulate 15 children from each age group.
Ages Eligible for Study: | 4 Years to 13 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | Yes |
Inclusion Criteria:
Exclusion Criteria:
Contact: Mun-Wai Lee, FRCS(G) | 65-63228378 | lee.mun.wai@singhealth.com.sg |
Contact: Yvonne Ling, FRCS(Ed) | 65-63228335 | yvonne.ling.l.f@snec.com.sg |
Singapore | |
Singapore National Eye Centre | Recruiting |
Singapore, Singapore, 168751 | |
Principal Investigator: Mun-Wai Lee, FRCS(G) |
Principal Investigator: | Yvonne Ling, FRCS(G) | Singapore National Eye Centre |
Study ID Numbers: | R456/05/2006 |
Study First Received: | June 30, 2006 |
Last Updated: | October 17, 2006 |
ClinicalTrials.gov Identifier: | NCT00347347 History of Changes |
Health Authority: | Singapore: Domain Specific Review Boards |
Mydriatics Eye Diseases Myopia Refractive Errors |
Eye Diseases Refractive Errors |