Home
Search
Study Topics
Glossary
|
|
|
|
|
Sponsored by: |
Merck |
---|---|
Information provided by: | Merck |
ClinicalTrials.gov Identifier: | NCT00442338 |
The study estimates the efficacy and safety of MK0476 and aminophylline intravenous administration in adult patients with acute asthma.
Condition | Intervention | Phase |
---|---|---|
Asthma |
Drug: montelukast Drug: Comparator: Aminophylline |
Phase III |
Study Type: | Interventional |
Study Design: | Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study |
Official Title: | MK0476 Phase III Open Label Exploratory Comparative Clinical Study -Acute Exacerbations of Asthma - |
Enrollment: | 90 |
Study Start Date: | February 2007 |
Primary Completion Date: | August 2007 (Final data collection date for primary outcome measure) |
Arms | Assigned Interventions |
---|---|
1: Experimental
Montelukast
|
Drug: montelukast
Montelukast single injection
|
2: Active Comparator
Aminophylline
|
Drug: Comparator: Aminophylline
Aminophylline single injection
|
Ages Eligible for Study: | 15 Years to 75 Years |
Genders Eligible for Study: | Both |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
Exclusion Criteria:
Responsible Party: | Merck & Co., Inc. ( Executive Vice President, Clinical and Quantitative Sciences ) |
Study ID Numbers: | 2007_007, MK0476-334 |
Study First Received: | February 27, 2007 |
Last Updated: | August 8, 2008 |
ClinicalTrials.gov Identifier: | NCT00442338 History of Changes |
Health Authority: | Japan: Pharmaceuticals and Medical Devices Agency |
Bronchial Diseases Hormone Antagonists Hormones, Hormone Substitutes, and Hormone Antagonists Asthma Anti-Asthmatic Agents Cardiovascular Agents Hormones Leukotriene Antagonists Montelukast Lung Diseases, Obstructive |
Hypersensitivity Phosphodiesterase Inhibitors Respiratory Tract Diseases Lung Diseases Aminophylline Hypersensitivity, Immediate Peripheral Nervous System Agents Bronchodilator Agents Respiratory Hypersensitivity |
Respiratory System Agents Bronchial Diseases Molecular Mechanisms of Pharmacological Action Cardiotonic Agents Hormone Antagonists Physiological Effects of Drugs Hormones, Hormone Substitutes, and Hormone Antagonists Leukotriene Antagonists Hypersensitivity Lung Diseases, Obstructive Respiratory Tract Diseases Therapeutic Uses Aminophylline Immune System Diseases |
Asthma Anti-Asthmatic Agents Enzyme Inhibitors Cardiovascular Agents Protective Agents Pharmacologic Actions Montelukast Phosphodiesterase Inhibitors Autonomic Agents Lung Diseases Hypersensitivity, Immediate Peripheral Nervous System Agents Bronchodilator Agents Respiratory Hypersensitivity |