Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema

This study is not yet open for participant recruitment.

Verified by Odense University Hospital, February 2007

First Received: February 28, 2007 No Changes Posted

Sponsored by:	Odense University Hospital
Information provided by:	Odense University Hospital
ClinicalTrials.gov Identifier:	NCT00442091

Purpose

Dandelion juice has been used in herbal medicine for at least 1000 years. Vesicular hand eczema is a rare, but difficult to treat, type of hand eczema.

One case report has shown that ingestion of dandelion juice could induce a beneficial effect on this type of eczema. The purpose of this study is to test whether this effect can be retrieved in other patients.

Condition	Intervention
Vesicular Palmoplantar Eczema Pompholyx	Drug: dandelion juice marketed as a dietary supplement in Denmark

MedlinePlus related topics: Eczema

U.S. FDA Resources

Study Type:	Interventional
Study Design:	Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Efficacy Study
Official Title:	Dandelion Juice in the Treatment of Dyshidrotic Hand Eczema

Further study details as provided by Odense University Hospital:

Primary Outcome Measures:

Improvement of dyshidrotic hand eczema in the study period.

Estimated Enrollment:	4
Study Start Date:	May 2007
Estimated Study Completion Date:	May 2007

Detailed Description:

Dandelion juice has been used in herbal medicine for at least 1000 years. One case report has shown a beneficial effect of this herbal remedy on dyshidrotic hand eczema, and the purpose of this pilot study is to test whether this effect can be retrieved in other patients.

The patients are recruited from our out-patient clinic. Only patients with negative patch tests to Compositae are offered treatment with dandelion juice for 20-30 days.

Eligibility

Ages Eligible for Study:	18 Years and older
Genders Eligible for Study:	Both
Accepts Healthy Volunteers:	No

Criteria

Inclusion Criteria:

Adult patients with dyshidrotic eczema for at least 1 year and negative patch test reactions to Compositae (tested within the last 3 years) and normal renal and hepatic blood tests.

Exclusion Criteria:

Treatment with systemic steroids or other immunosuppressive/-modulating drugs, including UV therapy, within the last 3 months.
Pregnancy, lactation.
Compositae contact allergy.
Liver or gall bladder disease.
Abnormal renal or hepatic blood tests.

Contacts and Locations

Please refer to this study by its ClinicalTrials.gov identifier: NCT00442091

Contacts

Contact: Evy Paulsen, Dr.

+6541 2705

evy.paulsen@regionsyddanmark.dk

Locations

Denmark
Department of Dermatology, Odense University Hospital
Odense, Denmark, DK-5000

Sponsors and Collaborators

Odense University Hospital

Investigators

Principal Investigator:

Evy Paulsen, Dr.

Department of Dermatology, Odense University Hospital, DK-5000 Odense C

More Information

No publications provided

Study ID Numbers:	20070010
Study First Received:	February 28, 2007
Last Updated:	February 28, 2007
ClinicalTrials.gov Identifier:	NCT00442091 History of Changes
Health Authority:	Denmark: Ethics Committee

Keywords provided by Odense University Hospital:

Dandelion
herbal remedy
hand eczema
Compositae

Study placed in the following topic categories:

Skin Diseases, Vesiculobullous
Skin Diseases
Skin Diseases, Eczematous

Eczema, Dyshidrotic
Eczema
Dermatitis

Additional relevant MeSH terms:

Skin Diseases, Vesiculobullous
Skin Diseases
Skin Diseases, Eczematous

Eczema, Dyshidrotic
Eczema
Dermatitis

ClinicalTrials.gov processed this record on May 07, 2009